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Home / Equine Research Bank / Equine Vet Educ / A review of foal diarrhoea from birth to weaning.
Equine veterinary education2012; 24(4); 206-214; doi: 10.1111/j.2042-3292.2011.00358.x

A review of foal diarrhoea from birth to weaning.

Abstract: Diarrhoea is among the most common clinical complaints in foals. Aetiologies, diagnostic testing and recommended interventions for specific causes of enterocolitis are summarised. Many mild to moderately affected foals can be managed in an ambulatory setting, while others will benefit from more intensive care at a referral centre.
© 2012 EVJ Ltd.
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Publication Date: 2012-01-18 PubMed ID: 32313387PubMed Central: PMC7163619DOI: 10.1111/j.2042-3292.2011.00358.xGoogle Scholar: Lookup
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Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

The research article deals with understanding the causes, diagnostics, and potential treatments for cases of diarrhoea in foals from birth to weaning.

Overview of the Research

  • The article presents a detailed survey of foal diarrhoea, which is one of the widespread clinical issues in foals. It delves into various causes or aetiologies, diagnostic procedures and suggested treatments or interventions specific to different causes of enterocolitis.

Aetiologies

  • The paper discusses different causes of diarrhoea in foals, otherwise known as aetiologies. These could include bacterial, viral or parasitic infections, dietary changes, medication side-effects, or other underlying health conditions. Understanding the root cause of the condition is crucial for selecting the appropriate treatment method.

Diagnostic Testing

  • The research also provides a summary of diagnostic tests which can be employed to determine the exact cause of diarrhoea. The kind of diagnostic examinations will depend on the suspected cause, and may encompass stool culture, blood tests, ultrasound, or endoscopy. The chosen test would provide veterinarians with vital information to design a suitable treatment plan.

Interventions

  • The article outlines recommended interventions that are tailored for specific sources of enterocolitis, an inflammatory disorder that affects the digestive tract. Depending on the foal’s condition and the cause of illness, interventions may involve dietary adjustments, antibiotics, intravenous fluids, or other types of medication.

Care and Management

  • The research emphasizes that not all foals suffering from diarrhoea will require high-intensity care at a referral centre. Many mild to moderately affected foals can be efficaciously managed in an ambulatory setting, i.e., under regular conditions where the foals can move freely. This indicates a need for veterinary practitioners to lean towards ambulatory care, unless the severity of the condition warrants a more intense, specialized care setting.

Cite This Article

APA
Mallicote M, House AM, Sanchez LC. (2012). A review of foal diarrhoea from birth to weaning. Equine Vet Educ, 24(4), 206-214. https://doi.org/10.1111/j.2042-3292.2011.00358.x

Publication

Equine veterinary education
ISSN: 0957-7734
NlmUniqueID: 9885274
Country: England
Language: English
Volume: 24
Issue: 4
Pages: 206-214

Researcher Affiliations

Mallicote, M
  • University of Florida College of Veterinary Medicine, Large Animal Clinical Sciences, Gainesville, Florida, USA.
House, A M
  • University of Florida College of Veterinary Medicine, Large Animal Clinical Sciences, Gainesville, Florida, USA.
Sanchez, L C
  • University of Florida College of Veterinary Medicine, Large Animal Clinical Sciences, Gainesville, Florida, USA.

References

This article includes 100 references
  1. Allan MJ. Pharmacokinetics of cefquinome after parenteral administration of an aqueous solution in the horse.. J. Vet. Pharmacol. Ther. 2003;26:104.
  2. Arguedas MG, Hines MT, Papich MG, Farnsworth KD, Sellon DC. Pharmacokinetics of butorphanol and evaluation of physiologic and behavioral effects after intravenous and intramuscular administration to neonatal foals.. J. Vet. Intern. Med. 2008;22:1417‐1426.
    pubmed: 18976284
  3. Arroyo LG, Weese JS, Staempfli HR. Experimental Clostridium difficile enterocolitis in foals.. J. Vet. Intern. Med. 2004;18:734‐738.
    pubmed: 15515592
  4. Atherington R, McKenzie H. Alternative antimicrobial agents in the treatment of proliferative enteropathy in horses.. J. Equine Vet. Sci. 2006;26:535‐541.
  5. Barr B, Wilkins P, Del Piero F. Is prophylaxis for gastric ulcers necessary in critically ill neonates? A retrospective study of necropsy cases 1995–1999.. Proceedings of the 18th Annual Meeting of the Veterinary Medical Forum, ACVIM, Seattle 2000;p 705.
  6. Barrandeguy M, Parreño V, Lagos Mármol M, Pont Lezica F, Rivas C, Valle C, Fernandez F. Prevention of rotavirus diarrhoea in foals by parenteral vaccination of the mares: field trial.. Dev. Biol. Stand. 1998;92:253‐257.
    pubmed: 9580371
  7. Båverud V, Gustafsson A, Franklin A, Aspán A, Gunnarsson A. Clostridium difficile: prevalence in horses and environment, and antimicrobial susceptibility.. Equine Vet. J. 2003;35:465‐471.
    pubmed: 12875324
  8. Brown M, Gronwall R, Boos D, Beal C. Aqueous procaine Penicillin‐G in foals – serum concentrations and pharmacokinetics after a single intramuscular dose.. Equine Vet. J. 1984;16:374‐375.
    pubmed: 6479138
  9. Brown CA, MacKay RJ, Chandra S, Davenport D, Lyons ET. Overwhelming strongyloidosis in a foal.. J. Am. Vet. Med. Ass. 1997;211:333‐334.
    pubmed: 9262674
  10. Browning G, Chalmers R, Snodgrass D, Batt R, Hart C, Ormarod S, Leadon D, Stoneham S, Rossdale P. The prevalence of enteric pathogens in diarrhoeic Thoroughbred foals in Britain and Ireland.. Equine Vet. J. 1991;23:405‐409.
    pmc: PMC7185455pubmed: 1663866
  11. Bucki EP, Giguère S, Macpherson M, Davis R. Pharmacokinetics of Once‐Daily Amikacin in healthy foals and therapeutic drug monitoring in hospitalized equine neonates.. J. Vet. Intern. Med. 2004;18:728.
    pubmed: 15515591
  12. Buechner‐Maxwell VA. Enteral feeding of sick newborn foals.. Comp. Cont. Educ. Pract. Vet. 1998;20:222.
  13. Buechner‐Maxwell VA. Nutritional support for neonatal foals.. Vet. Clin. N. Am.: Equine Pract. 2005;21:487‐510.
    pubmed: 16051059
  14. Bueschel D, Walker R, Woods L, Kokai‐Kun J, McClane B, Songer JG. Enterotoxigenic Clostridium perfringens type A necrotic enteritis in a foal.. J. Am. Vet. Med. Ass. 1998;213:1305‐1307.
    pubmed: 9810388
  15. Cole D, Cohen N, Snowden K, Smith R. Prevalence of and risk factors for fecal shedding of Cryptosporidium parvum oocysts in horses.. J. Am. Vet. Med. Ass. 1998;213:1296‐1302.
    pubmed: 9810386
  16. Conner ME, Darlington RW. Rotavirus infection in foals.. Am. J. Vet. Res. 1980;41:1699‐1703.
    pubmed: 6261616
  17. Corley KTT, Hollis AR. Antimicrobial therapy in neonatal foals.. Equine Vet. Educ. 2009;21:436‐448.
  18. Corrier DE, Montgomery D, Scutchfield WL. Adenovirus in the intestinal epithelium of a foal with prolonged diarrhea.. Vet. Pathol. 1982;19:564‐567.
    pubmed: 6293145
  19. Crill C, Hak E. Upper gastrointestinal tract bleeding in critically ill pediatric patients.. Pharmacotherapy 1999;19:162‐180.
    pubmed: 10030767
  20. Crisman MV, Wilcke JR, Sams RA. Pharmacokinetics of flunixin meglumine in healthy foals less than twenty‐four hours old.. Am. J. Vet. Res. 1996;57:1759‐1761.
    pubmed: 8950431
  21. Cudd TA, Pauly TH. Necrotizing enterocolitis in two equine neonates.. Comp. Cont. Educ. Pract. Vet. 1987;9:88.
  22. Cymbaluk NF, Smart ME, Bristol FM, Pouteaux VA. Importance of milk replacer intake and composition in rearing orphan foals.. Can. Vet. J 1993;34:479‐486.
    pmc: PMC1686398pubmed: 17424268
  23. Davis E, Rush BR, Cox J, DeBey B, Kapil S. Neonatal enterocolitis associated with coronavirus infection in a foal: a case report.. J. Vet. Diagn. Invest. 2000;12:153‐156.
    pubmed: 10730946
  24. Desrochers A, Dolente B, Roy M, Boston RC, Carlisle S. Efficacy of Saccharomyces boulardii for treatment of horses with acute enterocolitis.. J. Am. Vet. Med. Ass. 2005;227:954‐959.
    pubmed: 16190596
  25. Dinsmore J, Jackson R, Smith S. The protective role of gastric acidity in neonatal bacterial translocation.. J. Pediatr. Surg. 1997;32:1014‐1016.
    pubmed: 9247224
  26. Durr A. Comparison of the pharmacokinetics of Penicillin‐G and ampicillin in the horse.. Res. vet. Sci. 1976;20:24.
    pubmed: 1257624
  27. Dwyer R. Control and prevention of foal diarrhea outbreaks.. Proc. Am. Ass. Equine Practnrs 2001;47:472‐475.
  28. East L, Savage C, Traub‐Dargatz J, Dickinson C, Ellis R. Enterocolitis associated with Clostridium perfringens infection in neonatal foals: 54 cases (1988–1997).. J. Am. Vet. Med. Ass. 1998;212:1751‐1756.
    pubmed: 9621884
  29. Ensink JM, Klein WR, Barneveld A, Vulto AG, Miert AS. Clinical efficacy of ampicillin, pivampicillin and procaine penicillin G in a soft tissue infection model in ponies.. J. Vet. Pharmacol. Ther. 1996;19:445‐453.
    pubmed: 8971673
  30. Eser MW, Feige K, Furst A, Kummer M, von Bomhard W, Phillip M. Necrotizing enterocolitis in a mature newborn foal.. Pferdeheilkunde 2002;18:451+.
  31. Frazer M. Lawsonia intracellularis infection in horses: 2005–2007.. J. Vet. Intern. Med. 2008;22:1243‐1248.
    pubmed: 18681919
  32. Frederick J, Giguere S, Sanchez LC. Infectious agents detected in the feces of diarrheic foals: a retrospective study of 233 cases (2003–2008).. J. Vet. Intern. Med. 2009;23:1254‐1260.
    pmc: PMC7166729pubmed: 19747192
  33. Giguère S. Antimicrobial therapy. The Equine Hospital Manual 2008;1st edn., pp 337‐361.
  34. Grinberg A, Pomroy WE, Carslake HB, Shi Y, Gibson IR, Drayton BM. A study of neonatal cryptosporidiosis of foals in New Zealand.. N. Z. Vet. J. 2009;57:284‐289.
    pubmed: 19802042
  35. Grinberg A, Learmonth J, Kwan E, Pomroy W, Lopez Villalobos N, Gibson I, Widmer G. Genetic diversity and zoonotic potential of cryptosporidium parvum causing foal diarrhea.. J. Clin. Microbiol. 2008;46:2396‐2398.
    pmc: PMC2446936pubmed: 18508944
  36. Guy JS, Breslin JJ, Breuhaus B, Vivrette S, Smith LG. Characterization of a coronavirus isolated from a diarrheic foal.. J. Clin. Microbiol. 2000;38:4523‐4526.
    pmc: PMC87631pubmed: 11101590
  37. Halbert ND, Reitzel RA, Martens RJ, Cohen ND. Evaluation of a multiplex polymerase chain reaction assay for simultaneous detection of Rhodococcus equi and the vapA gene.. Am. J. Vet. Res. 2005;66:1380‐1385.
    pubmed: 16173481
  38. Hammock PD, Freeman DE, Baker GJ. Failure of psyllium mucilloid to hasten evaluation of sand from the equine large intestine.. Vet. Surg. 1998;27:547‐554.
    pubmed: 9845218
  39. Holland RE, Schmidt A, Sriranganathan N, Grimes SD, Wilson RA, Brown CM, Walker RD. Characterization of Escherichia coli isolated from foals.. Vet. Microbiol. 1996;48:243‐255.
    pubmed: 9054121
  40. Holland RE, Sriranganathan N, DuPont L. Isolation of enterotoxigenic Escherichia coli from a foal with diarrhea.. J. Am. Vet. Med. Ass. 1989;194:389‐391.
    pubmed: 2563724
  41. Hollis AR, Wilkins PA, Palmer JE, Boston RC. Bacteremia in equine neonatal diarrhea: a retrospective study (1990–2007).. J. Vet. Intern. Med. 2008;22:1203‐1209.
    pubmed: 18638014
  42. Hotwagner K, Iben C. Evacuation of sand from the equine intestine with mineral oil, with and without psyllium.. J. Anim. Physiol. Anim. Nutr. 2007;92:86‐91.
    pubmed: 18184383
  43. John G, Vankruiningen H, Reim D, Wachtel A. Fatal potomac horse fever (Ehrlichial colitis) in a foal: a case report from Connecticut.. J. Equine Vet. Sci. 1989;9:250‐252.
  44. Johnston R, Kamstra L, Kohler P. Mares' milk composition as related to ‘foal heat’ scours.. J. Anim. Sci. 1970;31:549‐553.
    pubmed: 5535335
  45. Jones P, Tomasic M, Gentry P. Oncotic, hemodilutional, and hemostatic effects of isotonic saline and hydroxyethyl starch solutions in clinically normal ponies.. Am. J. Vet. Res. 1997;58:541‐548.
    pubmed: 9140565
  46. Jones RL, Adney WS, Shideler RK. Isolation of Clostridium difficile and detection of cytotoxin in the feces of diarrheic foals in the absence of antimicrobial treatment.. J. Clin. Microbiol. 1987;25:1225‐1227.
    pmc: PMC269181pubmed: 3112178
  47. Kappstein I, Schulgen G, Friedrich T, Hellinger P, Benzing A, Geiger K, Daschner F. Incidence of pneumonia in mechanically ventilated patients treated with sucralfate or cimetidine as prophylaxis for stress bleeding ‐ bacterial colonization of the stomach.. Am. J. Med. 1991;91:S125‐S131.
    pubmed: 1882899
  48. Koterba A. Equine Clinical Neonatology. Lea & Febiger, Philadelphia 1990.
  49. Kuhl J, Winterhoff N, Wulfa M, Schweigert FJ, Schwendenwein I, Bruckmaier RM, Aurich JE, Kutzer P, Aurich C. Changes in faecal bacteria and metabolic parameters in foals during the first six weeks of life.. Vet. Microbiol. 2011;151:321‐328.
    pubmed: 21511405
  50. Landes A, Hassel D, Funk J, Hill A. Fecal sand clearance is enhanced with a product combining probiotics, prebiotics, and psyllium in clinically normal horses.. J. Equine Vet. Sci. 2008;28:79‐84.
  51. Lawler J, Hassel D, Magnuson R, Hill A, McCue P, Traub‐Dargatz J. Adsorptive effects of di‐tri‐octahedral smectite on Clostridium perfringens alpha, beta, and beta‐2 exotoxins and equine colostral antibodies.. Am. J. Vet. Res. 2008;69:233‐239.
    pubmed: 18241021
  52. Leib S. Sand removal from the GI tract of equine.. Proceedings of the 15th Equine Nutrition and Physiology Symposium, Fort Worth, TX, Equine Science Society, Champaign 1997;p 335.
  53. Lester G. Foal Diarrhea. Current Therapy in Equine Medicine 2003;pp 677‐680.
  54. Magdesian K. Colloid replacement in the ICU.. Clin. Tech. Equine Pract. 2003;2:130‐137.
  55. Magdesian K. Neonatal foal diarrhea.. Vet. Clin. N. Am.: Equine Pract. 2005;21:295‐312.
    pmc: PMC7135406pubmed: 16051051
  56. Magdesian K, Hogan PM, Cohen ND, Brumbaugh GW, Bernard WV. Pharmacokinetics of a high dose of gentamicin administered intravenously or intramuscularly to horses.. J. Am. Vet. Med. Ass. 1998;213:1007‐1011.
    pubmed: 9776999
  57. Magdesian KG, Hirsh DC, Jang SS, Hansen LM, Madigan JE. Characterization of Clostridium difficile isolates from foals with diarrhea: 28 cases (1993–1997).. J. Am. Vet. Med. Ass. 2002;220:67‐73.
    pubmed: 12680451
  58. Masri MD, Merritt AM, Gronwall R, Burrows CF. Faecal composition in foal heat diarrhoea.. Equine Vet. J. 1986;18:301‐306.
    pubmed: 3758010
  59. McAuliffe SB, Slovis NM. Color Atlas of Diseases and Disorders of the Foal. Saunders Elsevier, Philadelphia 2008;pp 104.
  60. McChesney A, England J, Rich L. Adenoviral infection in foals.. J. Am. Vet. Med. Ass. 1973;162:545‐549.
    pubmed: 4348198
  61. McFarlane D. Hetastarch: a synthetic colloid with potential in equine patients.. Compend. Cont. Educ. Pract. Vet. 1999;21:867‐873.
  62. McKenzie HC, Furr MO. Aminoglycoside antibiotics in neonatal foals.. Comp. Cont. Educ. Pract. Vet. 2003;25:457‐469.
  63. McKenzie HC, Geor RJ. Feeding management of sick neonatal foals.. Vet. Clin. N. Am.: Equine Pract. 2009;25:109‐119.
    pubmed: 19303554
  64. Medina‐Torres CE, Weese JS, Staempfli HR. Prevalence of Clostridium difficile in horses.. Vet. Microbiol. 2011;152:212‐215.
    pubmed: 21570780
  65. Meyer S, Giguère S, Rodriguez R, Zielinski RJ, Grover GS, Brown SA. Pharmacokinetics of intravenous ceftiofur sodium and concentration in body fluids of foals.. J. Vet. Pharmacol. Ther. 2009;32:309‐316.
    pubmed: 19614835
  66. Myers L, Shoop D, Byars T. Diarrhea associated with enterotoxigenic Bacteroides fragilis in foals.. Am. J. Vet. Res. 1987;48:1565‐1567.
    pubmed: 3434899
  67. Netherwood T, Binns M, Townsend H, Wood JL, Mumford JA, Chanter N. The Clostridium perfringens enterotoxin from equine isolates; its characterization, sequence and role in foal diarrhoea.. Epidemiol. Infect. 1998;120:193‐200.
    pmc: PMC2809390pubmed: 9593490
  68. Netherwood T, Wood JL, Townsend HG, Mumford JA, Chanter N. Foal diarrhoea between 1991 and 1994 in the United Kingdom associated with Clostridium perfringens, rotavirus, Strongyloides westeri and Cryptosporidium spp.. Epidemiol. Infect. 1996;117:375‐383.
    pmc: PMC2271710pubmed: 8870636
  69. Ortiz JE, Sottile FD, Sigel P, Nasraway SA. Gastric colonization as a consequence of stress ulcer prophylaxis: a prospective, randomized trial.. Pharmacotherapy 1998;18:486‐491.
    pubmed: 9620099
  70. Ousey J, Prandi S, Zimmer J, Holdstock N, Rossdale P. Effects of various feeding regimens on the energy balance of equine neonates.. Am. J. Vet. Res. 1997;58:1243‐1251.
    pubmed: 9361886
  71. Pantaleon L, Furr M, McKenzie H, Donaldson L. Effects of small‐ and large‐volume resuscitation on coagulation and electrolytes during experimental endotoxemia in anesthetized horses.. J. Vet. Intern. Med. 2007;21:1374‐1379.
    pubmed: 18196749
  72. Porter M, Green E. Blood and blood component therapy. Current Therapy in Equine Medicine 2003;pp 355‐357.
  73. Powell D, Dwyer R, Traub‐Dargatz J, Fulker R, Whalen J, Srinivasappa J, Acree W, Chu H. Field study of the safety, immunogenicity, and efficacy of an inactivated equine rotavirus vaccine.. J. Am. Vet. Med. Ass. 1997;211:193‐196.
    pubmed: 9227750
  74. Pusterla N, Gebhart C. Equine proliferative enteropathy caused by Lawsonia intracellularis.. Equine Vet. Educ. 2009;21:415‐419.
    pmc: PMC7163693pubmed: 32313386
  75. Pusterla N, Wilson WD, Mapes S, Lelitenegger CM. Diagnostic evaluation of real‐time PCR in the detection of Rhodococcus equi in faeces and nasopharyngeal swabs from foals with pneumonia.. Vet. Rec. 2007;161:272‐274.
    pubmed: 17720966
  76. Reuss S, Chaffin M, Cohen N. Extrapulmonary disorders associated with Rhodococcus equi infection in foals: 150 cases (1987–2007).. J. Am. Vet. Med. Ass. 2009;235:855‐863.
    pubmed: 19793018
  77. Roberts V, Knottenbelt D, Williams A, McKane S. Suspected primary lactose intolerance in neonatal foals.. Equine Vet. Educ. 2008;20:249‐251.
  78. Rodich N, Zschiesche E, Heckeroth A, Wilhelm C. Treatment of septicaemia and severe bacterial infections in foals with a new cefquinome formulation: a field study.. Dtsch Tierarztl. Wochenschr. 2009;116:316‐320.
    pubmed: 19813447
  79. Sampieri F, Hinchcliff KW, Toribio RE. Tetracycline therapy of Lawsonia intracellularis enteropathy in foals.. Equine Vet. J. 2010;38:89‐92.
    pubmed: 16411593
  80. Sanchez L, Giguere S, Lester G. Factors associated with survival of neonatal foals with bacteremia and racing performance of surviving Thoroughbreds: 423 cases (1982–2007).. J. Am. Vet. Med. Ass. 2008;233:1446‐1452.
    pubmed: 18980499
  81. Seahorn JL, Seahorn TL. Fluid therapy in horses with gastrointestinal disease.. Vet. Clin. N. Am.: Equine Pract. 2003;19:665‐679.
    pubmed: 14740762
  82. Sellon D, Besser T, Vivrette S, McConnico R. Comparison of nucleic ACid amplification, serology and microbiologic culture for diagnosis of rhodococcus equi pneumonia in foals.. J. Clin. Microbiol. 2001;39:1289‐1293.
    pmc: PMC87926pubmed: 11283043
  83. Semrad SD, Sams RA, Ashcraft SM. Pharmacokinetics of and serum thromboxane suppression by flunixin meglumine in healthy foals during the first month of life.. Am. J. Vet. Res. 1993;54:2083‐2087.
    pubmed: 8116942
  84. Sloet van Oldruitenborgh‐Oosterbaan M. Lactose intolerance in foals.. Equine Vet. Educ. 2008;20:252‐255.
  85. Slovis N, Elam J, Estrada M, Thao MF, Leutenegger C. Comprehensive analysis of infectious agents associated with diarrhea in foals in Central Kentucky.. Proc. Am. Ass. Equine Practnrs 2010;56:262‐266.
    pmc: PMC7163618pubmed: 23773143
  86. Studdert MJ, Blackney MH. Isolation of an adenovirus antigenically distinct from equine adenovirus type 1 from diarrheic foal feces.. Am. J. Vet. Res. 1982;43:543‐544.
    pubmed: 6176153
  87. Sweeney RW, Sweeney CR, Soma LR, Woodward CB, Charlton CA. Pharmacokinetics of metronidazole given to horses by intravenous and oral routes.. Am. J. Vet. Res. 1986;47:1726‐1729.
    pubmed: 3752681
  88. Sykes B, Furr M. Equine endotoxaemia–a state‐of‐the‐art review of therapy.. Aust. Vet. J. 2005;83:45‐50.
    pubmed: 15971817
  89. Thomas E, Thomas V, Wilhelm C. Antibacterial activity of cefquinome against equine bacterial pathogens.. Vet. Microbiol. 2006;115:140‐147.
    pubmed: 16455213
  90. Tillotson K, Traub‐Dargatz JL, Dickinson CE, Ellis RP, Morley PS, Hyatt DR, Magnuson RJ, Riddle WT, Bolte D, Salman M. Population‐based study of fecal shedding of Clostridium perfringens in broodmares and foals.. J. Am. Vet. Med. Ass. 2002;220:342‐348.
    pubmed: 11829266
  91. Toutain PL, Reymond N, Laroute V, Garcia P, Popot MA, Bonnaire Y, Hirsch A, Narbe R. Pharmacokinetics of meloxicam in plasma and urine of horses.. Am. J. Vet. Res. 2004;65:1542‐1547.
    pubmed: 15566093
  92. Traub‐Dargatz J, Besser T. Salmonella. Equine Infectious Diseases 2007;pp 331‐345.
  93. Venugopalan V, Shriner KA, Wong‐Beringer A. Regulatory oversight and safety of probiotic use.. Emerg. Infect. Dis. 2010;16:1661‐1665.
    pmc: PMC3294522pubmed: 21029521
  94. Weese JS. Microbiologic evaluation of commercial probiotics.. J. Am. Vet. Med. Ass. 2002;220:794‐797.
    pubmed: 11918274
  95. Weese JS, Rousseau J. Evaluation of Lactobacillus pentosus WE7 for prevention of diarrhea in neonatal foals.. J. Am. Vet. Med. Ass. 2005;226:2031‐2034.
    pubmed: 15989186
  96. Weese JS, Parsons DA, Staempfli HR. Association of Clostridium difficile with enterocolitis and lactose intolerance in a foal.. J. Am. Vet. Med. Ass. 1999;214:229‐232.
    pubmed: 9926015
  97. Weese J, Staempfli HR, Prescott JF. Survival of Clostridium difficile and its toxins in equine feces: implications for diagnostic test selection and interpretation.. J. Vet. Diagn. Invest. 2000;12:332‐336.
    pubmed: 10907862
  98. Weese JS, Staempfli HR, Prescott JF. A prospective study of the roles of clostridium difficile and enterotoxigenic Clostridium perfringens in equine diarrhoea.. Equine Vet. J. 2001;33:403‐409.
    pubmed: 11469775
  99. Weese JS, Cote N, deGannes R. Evaluation of in vitro properties of di‐tri‐octahedral smectite on clostridial toxins and growth.. Equine Vet. J. 2003;35:638‐641.
    pubmed: 14649353
  100. Widmer A, Kummer M, Eser MW, Fürst A. Comparison of the clinical efficacy of cefquinome with the combination of penicillin G and gentamicin in equine patients.. Equine Vet. Educ. 2009;21:430‐435.

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  1. Penazzi L, Pagliara E, Nervo T, Ala U, Bertuglia A, Romano G, Hattab J, Tiscar PG, Bergagna S, Pagliasso G, Antoniazzi S, Cavallarin L, Valle E, Prola L. Dietary supplementation of new-born foals with free nucleotides positively affects neonatal diarrhoea management. Ir Vet J 2025 Mar 1;78(1):7.
    doi: 10.1186/s13620-025-00294-3pubmed: 40025599google scholar: lookup
  2. Haywood LMB, Sheahan BJ. A Review of Epithelial Ion Transporters and Their Roles in Equine Infectious Colitis. Vet Sci 2024 Oct 7;11(10).
    doi: 10.3390/vetsci11100480pubmed: 39453072google scholar: lookup
  3. Fikri F, Hendrawan D, Wicaksono AP, Purnomo A, Khairani S, Chhetri S, Maslamama ST, Purnama MTE. Incidence, risk factors, and therapeutic management of equine colic in Lamongan, Indonesia. Vet World 2023;16(7):1408-1414.
    doi: 10.14202/vetworld.2023.1408-1414pubmed: 37621536google scholar: lookup
  4. Zakia LS, Gomez DE, Caddey BB, Boerlin P, Surette MG, Arroyo LG. Direct and culture-enriched 16S rRNA sequencing of cecal content of healthy horses and horses with typhlocolitis. PLoS One 2023;18(4):e0284193.
    doi: 10.1371/journal.pone.0284193pubmed: 37053174google scholar: lookup
  5. Hain-Saunders NMR, Knight DR, Bruce M, Riley TV. Clostridioides difficile infection and One Health: an equine perspective. Environ Microbiol 2022 Mar;24(3):985-997.
    doi: 10.1111/1462-2920.15898pubmed: 35001483google scholar: lookup
  6. Goodman-Davis R, Figurska M, Cywinska A. Gut Microbiota Manipulation in Foals-Naturopathic Diarrhea Management, or Unsubstantiated Folly?. Pathogens 2021 Sep 4;10(9).
    doi: 10.3390/pathogens10091137pubmed: 34578169google scholar: lookup
  7. Reddy PRK, Yasaswini D, Reddy PPR, Zeineldin M, Adegbeye MJ, Hyder I. Applications, challenges, and strategies in the use of nanoparticles as feed additives in equine nutrition. Vet World 2020 Aug;13(8):1685-1696.
    doi: 10.14202/vetworld.2020.1685-1696pubmed: 33061246google scholar: lookup
  8. Mehdizadeh Gohari I, Unterer S, Whitehead AE, Prescott JF. NetF-producing Clostridium perfringens and its associated diseases in dogs and foals. J Vet Diagn Invest 2020 Mar;32(2):230-238.
    doi: 10.1177/1040638720904714pubmed: 32081091google scholar: lookup
  9. Oliver-Espinosa O. Foal Diarrhea: Established and Postulated Causes, Prevention, Diagnostics, and Treatments. Vet Clin North Am Equine Pract 2018 Apr;34(1):55-68.
    doi: 10.1016/j.cveq.2017.11.003pubmed: 29395727google scholar: lookup
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