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Journal of equine veterinary science2019; 80; 64-68; doi: 10.1016/j.jevs.2019.06.018

Accelerated Idioventricular Rhythm Associated With Isoflurane Administration in a Foal: A Case Report.

Abstract: A 2-day-old filly was referred to the hospital with abdominal pain and constipation. The foal presented tachycardia, tachypnea, hypoxemia, hyperlactatemia, and abdominal distension. Meconium impaction was diagnosed, and the filly underwent abdominal surgery. Diazepam and butorphanol were administered for anesthesia premedication, but sedative effects were mild. Xylazine was used to enhance sedation and ketamine was subsequently administered for induction. The foal showed swallow reflex and head movement when intubation was attempted. Consequently, isoflurane on oxygen was provided via an anesthetic face mask. After intubation, the foal was connected to the anesthetic machine and monitored. The electrocardiogram revealed accelerated idioventricular rhythm, characterized by atrioventricular isorhythmic dissociation with monomorphic wide QRS complexes. Lidocaine was administered but the arrhythmia persisted during anesthesia and was spontaneously corrected once the isoflurane was discontinued at the end of the procedure. The foal recovered from anesthesia without complications and no further cardiac events were observed before the patient being discharged. Accelerated idioventricular rhythm likely resulted from administration of isoflurane to a foal presenting hypoxemia, a condition that exacerbates the risk of arrhythmia. Proper management of this abnormal rhythm is crucial as inappropriate treatments may worsen the arrhythmia.
Publication Date: 2019-07-09 PubMed ID: 31443837DOI: 10.1016/j.jevs.2019.06.018Google Scholar: Lookup
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Summary

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This research article discusses a case study of a 2-day-old filly (young female horse) with abdominal issues, who developed an unusual heart rhythm due to the anaesthetic treatment used during surgery. The abnormal rhythm was managed and corrected after the procedure with no further complications.

Case Background

  • The subject of this case study was a 2-day-old baby horse who presented to a veterinary hospital with digestive issues including constipation and abdominal pain.
  • Other symptoms included fast heart rate (tachycardia), rapid breathing (tachypnea), and low oxygen in the blood (hypoxemia).
  • An analysis revealed the foal had an accumulation of meconium, the early stool passed by a newborn. This condition necessitated surgical intervention.

Anesthesia and Complications

  • The medical team administered several drugs to induce sedation and anaesthesia prior to the abdominal surgery.
  • During intubation, the foal showed some reflexive responses, indicating mild sedative effects.
  • As a result, the anesthetic isoflurane was administered along with oxygen, which resulted in an irregular heart rhythm called Accelerated Idioventricular Rhythm (AIVR) on the foal’s electrocardiogram.

Management of Accelerated Idioventricular Rhythm

  • This specific heart rhythm disorder is characterized by atrioventricular isorhythmic dissociation with wide and uniform QRS complexes, which was exhibited by the foal.
  • The arrhythmia persisted throughout the operation despite the administration of Lidocaine, an antiarrhythmic drug.
  • However, once isoflurane was discontinued at the end of the procedure, the arrhythmia spontaneously resolved itself, indicating a likely correlation between isoflurane administration and the onset of AIVR.

Postoperative Outcome

  • The foal recovered from anesthesia without any complications, and no further cardiac abnormalities were observed before the foal was discharged from the hospital.
  • The study concludes that the administration of isoflurane, especially under hypoxic conditions, may pose a risk of inducing AIVR. Accordingly, appropriate management and monitoring of such rhythm anomalies are vital to mitigate adverse effects and ensure recovery.

Cite This Article

APA
Peña-Cadahia C, Manso-Díaz G, Santiago-Llorente I, Villalba-Orero M. (2019). Accelerated Idioventricular Rhythm Associated With Isoflurane Administration in a Foal: A Case Report. J Equine Vet Sci, 80, 64-68. https://doi.org/10.1016/j.jevs.2019.06.018

Publication

ISSN: 0737-0806
NlmUniqueID: 8216840
Country: United States
Language: English
Volume: 80
Pages: 64-68
PII: S0737-0806(19)30071-1

Researcher Affiliations

Peña-Cadahia, Celia
  • Hospital Clínico Veterinario Complutense, Facultad de Veterinaria, Universidad Complutense de Madrid, Madrid, Spain; Departamento de Medicina y Cirugía Animal, Facultad de Veterinaria, Universidad Complutense de Madrid, Madrid, Spain.
Manso-Díaz, Gabriel
  • Hospital Clínico Veterinario Complutense, Facultad de Veterinaria, Universidad Complutense de Madrid, Madrid, Spain.
Santiago-Llorente, Isabel
  • Hospital Clínico Veterinario Complutense, Facultad de Veterinaria, Universidad Complutense de Madrid, Madrid, Spain.
Villalba-Orero, María
  • Hospital Clínico Veterinario Complutense, Facultad de Veterinaria, Universidad Complutense de Madrid, Madrid, Spain; Departamento de Medicina y Cirugía Animal, Facultad de Veterinaria, Universidad Complutense de Madrid, Madrid, Spain; Specialist Equine Cardiology Services, Madrid, Spain. Electronic address: mvorero@ucm.es.

MeSH Terms

  • Accelerated Idioventricular Rhythm / veterinary
  • Animals
  • Electrocardiography
  • Female
  • Horses
  • Isoflurane
  • Ketamine
  • Xylazine

Citations

This article has been cited 2 times.
  1. Sato K, Miyamae Y, Kan M, Sato S, Yaegashi M, Sakanoue W, Sakai H, Sakamoto S, Vaba K. Accelerated Idioventricular Rhythm Following Intraoral Local Anesthetic Injection During General Anesthesia. Anesth Prog 2021 Dec 1;68(4):230-234.
    doi: 10.2344/anpr-68-03-09pubmed: 34911065google scholar: lookup
  2. Xie C, Wang H, Zhang Y, Wei Y. Neuroprotective effects of miR-142-5p downregulation against isoflurane-induced neurological impairment. Diagn Pathol 2020 Jun 6;15(1):70.
    doi: 10.1186/s13000-020-00978-0pubmed: 32505188google scholar: lookup