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Journal of veterinary internal medicine2016; 30(3); 866-872; doi: 10.1111/jvim.13928

Accuracy and Precision of Noninvasive Blood Pressure in Normo-, Hyper-, and Hypotensive Standing and Anesthetized Adult Horses.

Abstract: Blood pressure is relevant to the diagnosis and management of many medical, cardiovascular and critical diseases. The accuracy of many commonly used noninvasive blood pressure (NIBP) monitors and the accuracy of NIBP measurements in hypo- and hypertensive standing horses has not been determined. Objective: The objective of this study was to investigate the accuracy of an oscillometric BP monitor in standing horses before and during pharmacologically induced hyper- and hypotension and to compare results in standing and anesthetized horses. Methods: Eight standing mares from a research herd (SG) and eight anesthetized horses from a hospital population (AG). Methods: Prospective experimental and observational studies. Invasive blood pressure (IBP) and NIBP, corrected to heart level, were measured simultaneously. In the SG hyper- and hypotension were induced by administration of phenylephrine (3 μg/kg/min IV for 15 minutes) and acepromazine (0.05 mg/kg IV), respectively. In the AG NIBP and IBP were recorded during regular hospital procedures. Results: There was a significant correlation between mean NIBP and IBP in standing (R = 0.88, P < .001) and anesthetized horses (R = 0.81, P < .001). The mean bias (lower, upper limit of agreement) was 16.4(-16.1, 48.9) mmHg for mean BP in the SG and 0.5(-22.3, 23.2) mmHg in the AG. The NIBP device was capable of identifying the increase and decrease in BP in all horses, but in the SG significant correlation between NIBP and IBP was only detected for the normotensive phase. Conclusions: While the evaluated oscillometric BP device allowed estimation of BP and adequately differentiated marked trends, the accuracy and precision were low in standing horses.
Copyright © 2016 The Authors. Journal of Veterinary Internal Medicine published by Wiley Periodicals, Inc. on behalf of the American College of Veterinary Internal Medicine.
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Publication Date: 2016-04-05 PubMed ID: 27059803PubMed Central: PMC4913577DOI: 10.1111/jvim.13928Google Scholar: Lookup
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  • Journal Article

Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

The article focuses on the study undertaken to determine the accuracy of noninvasive blood pressure monitors in diagnosing and managing blood pressure in standing and anesthetized horses during both normal and pharmaceutically-induced blood pressure conditions.

Research Objective

  • The article aims to explore how accurate an oscillometric Blood Pressure (BP) monitor is in recording blood pressure in horses. This is explored under two conditions – when the horses are standing and when they are anesthetized. Further, the research also looks into BP measurement during instances of pharmaceutically-induced hypertensive (high blood pressure) and hypotensive (low blood pressure) states.

Research Method

  • The research involves both prospective experimental and observational studies using a total of 16 horses. This includes eight standing mares from a research herd (SG) and eight anesthetized horses from a hospital population (AG).
  • Along with noninvasive blood pressure (NIBP) measurements, invasive blood pressure (IBP) measurements were also taken simultaneously for better comparison and accurate results.
  • The researchers induced hypertension and hypotension in the standing group by administering phenylephrine and acepromazine, respectively. Meanwhile, in the anesthetized group, NIBP and IBP were recorded during regular hospital procedures.

Research Findings

  • The study found a significant correlation between the mean NIBP and IBP in both standing (R = 0.88) and anesthetized horses (R = 0.81).
  • The NIBP device was proficient in detecting both the rise and fall in BP in all horses, but a significant correlation between NIBP and IBP was only established during the normotensive phase in the standing group.
  • However, the mean bias (that is, the degree of deviation towards one side) was found to be 16.4 mmHg for mean BP in the standing group and 0.5 mmHg in the anesthetized group.

Research Conclusion

  • The findings of the research suggest that while the oscillometric BP device does provide a decent estimation of blood pressure and successfully differentiates significant trends, its accuracy and precision in standing horses could be improved.

Cite This Article

APA
Heliczer N, Lorello O, Casoni D, Navas de Solis C. (2016). Accuracy and Precision of Noninvasive Blood Pressure in Normo-, Hyper-, and Hypotensive Standing and Anesthetized Adult Horses. J Vet Intern Med, 30(3), 866-872. https://doi.org/10.1111/jvim.13928

Publication

Journal of veterinary internal medicine
ISSN: 1939-1676
NlmUniqueID: 8708660
Country: United States
Language: English
Volume: 30
Issue: 3
Pages: 866-872

Researcher Affiliations

Heliczer, N
  • Swiss Institute of Equine Medicine, Department of Veterinary Clinical Science, School of Veterinary Medicine, Vetsuisse Faculty, University of Bern and Agroscope, Bern, Switzerland.
Lorello, O
  • Swiss Institute of Equine Medicine, Department of Veterinary Clinical Science, School of Veterinary Medicine, Vetsuisse Faculty, University of Bern and Agroscope, Bern, Switzerland.
Casoni, D
  • Anaesthesia Division, Vetsuisse Faculty, University of Bern and Agroscope, Bern, Switzerland.
Navas de Solis, C
  • Swiss Institute of Equine Medicine, Department of Veterinary Clinical Science, School of Veterinary Medicine, Vetsuisse Faculty, University of Bern and Agroscope, Bern, Switzerland.

MeSH Terms

  • Acepromazine
  • Anesthesia / veterinary
  • Animals
  • Blood Pressure / drug effects
  • Blood Pressure / physiology
  • Blood Pressure Determination / methods
  • Blood Pressure Determination / veterinary
  • Female
  • Horses / physiology
  • Hypertension / chemically induced
  • Hypertension / physiopathology
  • Hypotension / chemically induced
  • Hypotension / physiopathology
  • Male
  • Oscillometry / veterinary
  • Phenylephrine

References

This article includes 35 references
  1. Shih A. Cardiac output monitoring in horses.. Vet Clin North Am Equine Pract 2013 Apr;29(1):155-67.
    pubmed: 23498050doi: 10.1016/j.cveq.2012.11.002google scholar: lookup
  2. Marsh PS. Approach to equine critical care: Monitoring Arterial Blood Pressure. In: Reed SM, Bayly WM, Sellon DC, eds. Equine Imternal Medicine, 3rd ed St. Louis, MO: Saunder; 2010:254–256.
  3. Shoemaker WC. Invasive and noninvasive monitoring. In: Shoemaker WC, Ayres SM, Grenvik A, eds. Textbook of Critical Care, 4th ed Philadelphia, PA: Saunders; 2000:74–92.
  4. Rugh KS, Garner HE, Sprouse RF, Hatfield DG. Left ventricular hypertrophy in chronically hypertensive ponies.. Lab Anim Sci 1987 Jun;37(3):335-8.
    pubmed: 2956457
  5. Bailey SR, Habershon-Butcher JL, Ransom KJ, Elliott J, Menzies-Gow NJ. Hypertension and insulin resistance in a mixed-breed population of ponies predisposed to laminitis.. Am J Vet Res 2008 Jan;69(1):122-9.
    pubmed: 18167097doi: 10.2460/ajvr.69.1.122google scholar: lookup
  6. Navas de Solis C, Slack J, Boston RC, Reef VB. Hypertensive cardiomyopathy in horses: 5 cases (1995-2011).. J Am Vet Med Assoc 2013 Jul 1;243(1):126-30.
    pubmed: 23786201doi: 10.2460/javma.243.1.126google scholar: lookup
  7. Giguère S, Knowles HA Jr, Valverde A, Bucki E, Young L. Accuracy of indirect measurement of blood pressure in neonatal foals.. J Vet Intern Med 2005 Jul-Aug;19(4):571-6.
    pubmed: 16095176
  8. Branson KR. A clinical evaluation of an oscillometric blood pressure monitor on anesthetized horses. J Equine Vet Sci 1997;17:537–540.
  9. Nout YS, Corley KT, Donaldson LL, Furr MO. Indirect oscillometric and direct blood pressure measurements in anesthetized and conscious neonatal foals. J Vet Emerg Crit Care 2002;12:75–80.
  10. Gent TC, Schwarz A, Hatz LA. Evaluation of accuracy of invasive and non‐invasive blood pressure monitoring in relation to carotid artery pressure in anaesthetised ponies. Pferdeheilkunde 2015;31:33–38.
  11. Brown S, Atkins C, Bagley R, Carr A, Cowgill L, Davidson M, Egner B, Elliott J, Henik R, Labato M, Littman M, Polzin D, Ross L, Snyder P, Stepien R. Guidelines for the identification, evaluation, and management of systemic hypertension in dogs and cats.. J Vet Intern Med 2007 May-Jun;21(3):542-58.
    pubmed: 17552466doi: 10.1892/0891-6640(2007)21[542:gftiea]2.0.co;2google scholar: lookup
  12. Parry BW, McCarthy MA, Anderson GA. Survey of resting blood pressure values in clinically normal horses.. Equine Vet J 1984 Jan;16(1):53-8.
    pubmed: 6714207doi: 10.1111/j.2042-3306.1984.tb01853.xgoogle scholar: lookup
  13. Magdesian KG. Monitoring the critically ill equine patient.. Vet Clin North Am Equine Pract 2004 Apr;20(1):11-39.
    pubmed: 15062457doi: 10.1016/j.cveq.2003.12.001google scholar: lookup
  14. Pequito M, Amory H, Serteyn D. Comparison of the sedative and hemodynamic effects of acepromazine and promethazine in the standing horse. J Equine Vet Sci 2012;32:799–804.
  15. Leise BS, Fugler LA, Stokes AM, Eades SC, Moore RM. Effects of intramuscular administration of acepromazine on palmar digital blood flow, palmar digital arterial pressure, transverse facial arterial pressure, and packed cell volume in clinically healthy, conscious horses.. Vet Surg 2007 Dec;36(8):717-23.
    pubmed: 18067611doi: 10.1111/j.1532-950x.2007.00325.xgoogle scholar: lookup
  16. Hardy J, Bednarski RM, Biller DS. Effect of phenylephrine on hemodynamics and splenic dimensions in horses.. Am J Vet Res 1994 Nov;55(11):1570-8.
    pubmed: 7879981
  17. Bland JM, Altman DG. Measuring agreement in method comparison studies.. Stat Methods Med Res 1999 Jun;8(2):135-60.
    pubmed: 10501650doi: 10.1177/096228029900800204google scholar: lookup
  18. Tünsmeyer J, Hopster K, Feige K, Kästner SB. Agreement of high definition oscillometry with direct arterial blood pressure measurement at different blood pressure ranges in horses under general anaesthesia.. Vet Anaesth Analg 2015 May;42(3):286-91.
    pubmed: 25053371doi: 10.1111/vaa.12203google scholar: lookup
  19. Avolio AP, Van Bortel LM, Boutouyrie P, Cockcroft JR, McEniery CM, Protogerou AD, Roman MJ, Safar ME, Segers P, Smulyan H. Role of pulse pressure amplification in arterial hypertension: experts' opinion and review of the data.. Hypertension 2009 Aug;54(2):375-83.
    pubmed: 19564542doi: 10.1161/hypertensionaha.109.134379google scholar: lookup
  20. Kittleson MD, Olivier NB. Measurement of systemic arterial blood pressure.. Vet Clin North Am Small Anim Pract 1983 May;13(2):321-36.
    pubmed: 6604984doi: 10.1016/s0195-5616(83)50032-6google scholar: lookup
  21. Geddes LA, Voelz M, Combs C, Reiner D, Babbs CF. Characterization of the oscillometric method for measuring indirect blood pressure.. Ann Biomed Eng 1982;10(6):271-80.
    pubmed: 7171156doi: 10.1007/bf02367308google scholar: lookup
  22. Tearney CC, Guedes AG, Brosnan RJ. Equivalence between invasive and oscillometric blood pressures at different anatomic locations in healthy normotensive anaesthetised horses.. Equine Vet J 2016 May;48(3):357-61.
    doi: 10.1111/evj.12443pubmed: 25790220google scholar: lookup
  23. Podell M. Use of blood pressure monitors. In: Kirk R, Bonagura JD, eds. Kirk's Current Veterinary Therapy XI: Small Animal Practice. Philadelphia, PA: WB Saunders Co; 1992:834–837.
  24. Plumb DC. Phenylephrine. In: Plumb DC, ed. Plumb's Veterinary Drug Handbook. Ames: Blackwell Publishing; 2008:724.
  25. Plumb DC. Acepromazine maleate. In: Plumb DC, ed. Plumb's Veterinary Drug Handbook. Ames: Blackwell Publishing; 2008:3.
  26. Ursino M, Cristalli C. A mathematical study of some biomechanical factors affecting the oscillometric blood pressure measurement.. IEEE Trans Biomed Eng 1996 Aug;43(8):761-78.
    pubmed: 9216149doi: 10.1109/10.508540google scholar: lookup
  27. Muir WW, Wade A, Grospitch B. Automatic noninvasive sphygmomanometry in horses.. J Am Vet Med Assoc 1983 Jun 1;182(11):1230-3.
    pubmed: 6863140
  28. Caulkett NA, Cantwell SL, Houston DM. A comparison of indirect blood pressure monitoring techniques in the anesthetized cat.. Vet Surg 1998 Jul-Aug;27(4):370-7.
    pubmed: 9662782doi: 10.1111/j.1532-950x.1998.tb00143.xgoogle scholar: lookup
  29. Bosiack AP, Mann FA, Dodam JR, Wagner-Mann CC, Branson KR. Comparison of ultrasonic Doppler flow monitor, oscillometric, and direct arterial blood pressure measurements in ill dogs.. J Vet Emerg Crit Care (San Antonio) 2010 Apr 1;20(2):207-15.
    pubmed: 20487248doi: 10.1111/j.1476-4431.2010.00520.xgoogle scholar: lookup
  30. Latshaw H, Fessler JF, Whistler SJ, Geddes LA. Indirect measurement of mean blood pressure in the normotensive and hypotensive horse.. Equine Vet J 1979 Jul;11(3):191-4.
    pubmed: 488068doi: 10.1111/j.2042-3306.1979.tb01340.xgoogle scholar: lookup
  31. McMurphy RM, Stoll MR, McCubrey R. Accuracy of an oscillometric blood pressure monitor during phenylephrine-induced hypertension in dogs.. Am J Vet Res 2006 Sep;67(9):1541-5.
    pubmed: 16948598doi: 10.2460/ajvr.67.9.1541google scholar: lookup
  32. Binns SH, Sisson DD, Buoscio DA, Schaeffer DJ. Doppler ultrasonographic, oscillometric sphygmomanometric, and photoplethysmographic techniques for noninvasive blood pressure measurement in anesthetized cats.. J Vet Intern Med 1995 Nov-Dec;9(6):405-14.
    pubmed: 8558488doi: 10.1111/j.1939-1676.1995.tb03301.xgoogle scholar: lookup
  33. Parry BW, McCarthy MA, Anderson GA, Gay CC. Correct occlusive bladder width for indirect blood pressure measurement in horses.. Am J Vet Res 1982 Jan;43(1):50-4.
    pubmed: 7091817
  34. Gornik HL, Garcia B, Wolski K, Jones DC, Macdonald KA, Fronek A. Validation of a method for determination of the ankle-brachial index in the seated position.. J Vasc Surg 2008 Nov;48(5):1204-10.
    pubmed: 18829231doi: 10.1016/j.jvs.2008.06.052google scholar: lookup
  35. Ramsey M 3rd. Blood pressure monitoring: automated oscillometric devices.. J Clin Monit 1991 Jan;7(1):56-67.
    pubmed: 1999699doi: 10.1007/bf01617900google scholar: lookup

Citations

This article has been cited 15 times.
  1. Vitale V, Vezzosi T, Di Franco C, Briganti A, Tognetti R, Conte G, Bucchioni E, Sgorbini M. Equine echocardiography: Can dobutamine infusion correct alterations due to sedation with alpha-2 agonists?. PLoS One 2022;17(10):e0276256.
    doi: 10.1371/journal.pone.0276256pubmed: 36256667google scholar: lookup
  2. Pratt S, Barnes TS, Cowling N, de Klerk K, Rainger J, Sole-Guitart A, Woldeyohannes S, Goodwin W. Bias Associated with Peripheral Non-Invasive Compared to Invasive Arterial Blood Pressure Monitoring in Healthy Anaesthetised and Standing Horses Using the Bionet BM7Vet. Vet Sci 2022 Jan 28;9(2).
    doi: 10.3390/vetsci9020052pubmed: 35202305google scholar: lookup
  3. Twele L, Neudeck S, Delarocque J, Verhaar N, Reiners J, Noll M, Tünsmeyer J, Kästner SBR. Agreement of High-Definition Oscillometry (HDO) and Invasive Blood Pressure Measurements at a Metatarsal Artery in Isoflurane-Anaesthetised Horses. Animals (Basel) 2022 Feb 2;12(3).
    doi: 10.3390/ani12030363pubmed: 35158686google scholar: lookup
  4. Radhakrishnan S, Lorenzutti AM, Araos JD, Martin-Flores M. Evaluation of noninvasive blood pressure in anesthetized horses: Bias, limits of agreement, and comparative detection of a predetermined mean blood pressure warranting treatment. Can Vet J 2021 Sep;62(9):994-998.
    pubmed: 34475586
  5. Vera L, Muylle S, Van Steenkiste G, Segers P, Decloedt A, Chiers K, van Loon G. Histological and biomechanical properties of systemic arteries in young and old Warmblood horses. PLoS One 2021;16(7):e0253730.
    doi: 10.1371/journal.pone.0253730pubmed: 34252105google scholar: lookup
  6. Caffey SR, Lund CM, Farnsworth KD, Fransson BA, Ragle CA. Effects of head position on internal and external carotid pressures in standing sedated horses. Can J Vet Res 2021 Apr;85(2):127-130.
    pubmed: 33883820
  7. Skelding A, Valverde A. Review of non-invasive blood pressure measurement in animals: Part 2 - Evaluation of the performance of non-invasive devices. Can Vet J 2020 May;61(5):481-498.
    pubmed: 32355347
  8. Skelding A, Valverde A. Non-invasive blood pressure measurement in animals: Part 1 - Techniques for measurement and validation of non-invasive devices. Can Vet J 2020 Apr;61(4):368-374.
    pubmed: 32255821
  9. Vera L, De Clercq D, Van Steenkiste G, Decloedt A, Chiers K, van Loon G. Differences in ultrasound-derived arterial wall stiffness parameters and noninvasive blood pressure between Friesian horses and Warmblood horses. J Vet Intern Med 2020 Mar;34(2):893-901.
    doi: 10.1111/jvim.15705pubmed: 32032455google scholar: lookup
  10. Boegli J, Schwarzwald CC, Mitchell KJ. Diagnostic value of noninvasive pulse pressure measurements in Warmblood horses with aortic regurgitation. J Vet Intern Med 2019 May;33(3):1446-1455.
    doi: 10.1111/jvim.15494pubmed: 30938891google scholar: lookup
  11. Agne GF, Jung SW, Wooldridge AA, Duran SH, Ravis W, Toribio R. Pharmacokinetic and pharmacodynamic properties of orally administered torsemide in healthy horses. J Vet Intern Med 2018 Jul;32(4):1428-1435.
    doi: 10.1111/jvim.15213pubmed: 29770976google scholar: lookup
  12. Dufourni A, Demeyere M, Vernemmen I, Van Steenkiste G, Verhaeghe LM, van Loon G, Decloedt A. Effect of N-Butylscopolammonium Bromide and Metamizol Sodium on Heart Rate, Blood Pressure, and Echocardiographic Measurements in Warmblood Horses With Aortic and Mitral Valve Regurgitation. J Vet Intern Med 2025 Nov-Dec;39(6):e70254.
    doi: 10.1111/jvim.70254pubmed: 41070729google scholar: lookup
  13. Mendoza FJ, Buzon-Cuevas A, Aguilera-Aguilera R, Gonzalez-De Cara CA, De Las Heras A, Perez-Ecija A. Hemodynamic Response to Lipopolysaccharide Infusion and Effect of Meloxicam Administration on Cardiac Function in Donkeys. Animals (Basel) 2024 Dec 18;14(24).
    doi: 10.3390/ani14243660pubmed: 39765564google scholar: lookup
  14. Brown K, Williams Louie E, Pinn-Woodcock T, Pearson E, Pearson GB, Marr J, Hackett ES, Rath Brown L, Mitchell KJ. Cardiac Disease Related to Primary Hyperthyroidism in a 20-Year-Old Mule. Animals (Basel) 2024 Jun 1;14(11).
    doi: 10.3390/ani14111660pubmed: 38891707google scholar: lookup
  15. Dufourni A, Buschmann E, Vernemmen I, Van Steenkiste G, van Loon G, Decloedt A. Effect of physiological and pharmacological stress on heart rate, blood pressure, and echocardiographic measurements in healthy Warmblood horses. J Vet Intern Med 2024 Jan-Feb;38(1):398-410.
    doi: 10.1111/jvim.16967pubmed: 38174810google scholar: lookup
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