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Home / Equine Research Bank / Vet Parasitol / Acquired resistance of horses to Amblyomma cajennense (Fabri...
Veterinary parasitology2003; 117(4); 271-283; doi: 10.1016/j.vetpar.2003.09.004

Acquired resistance of horses to Amblyomma cajennense (Fabricius, 1787) ticks.

Abstract: Acquired immunity of horses to larvae, nymphs and adults of the Amblyomma cajennense tick was evaluated through three consecutive experimental infestations of tick-bite naïve hosts. Data from these infestations were compared to those from field-sensitized horses and donkeys. It was observed that tick-bite naïve horses developed a low level of resistance after two infestations as shown by a significant decrease in larval yield and a tendency for lower engorged weight of nymphs during third infestation. Ticks fed on field-sensitized horses had a similar biological performance to that observed on the third infestation of tick-bite naïve horses but the mean engorged nymph weight was significantly lower than that of the first infestation from tick-bite naïve horses. Donkeys presented the strongest resistance with significantly lower engorged weights of all instars and of the egg mass compared to the first infestation of tick-bite naïve horses. Donkeys also displayed a significantly higher resistance than field-sensitized horses as demonstrated by significantly lower egg mass weights. Overall these results indicate that donkeys but not horses maintain a strong resistance to A. cajennense ticks. The importance of these findings in relation to vectoring of tick-borne diseases is discussed.
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Publication Date: 2003-11-26 PubMed ID: 14637029DOI: 10.1016/j.vetpar.2003.09.004Google Scholar: Lookup
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  • Journal Article
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  • Non-U.S. Gov't

Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

The research studied resistance levels in horses and donkeys to the Amblyomma cajennense tick, through multiple infestations. It revealed that horses developed mild resistance after a couple of exposures, while donkeys showed considerably stronger resistance.

Methodology

  • The researchers conducted three consecutive experimental infestations of Amblyomma cajennense ticks on horses that had not been exposed to the ticks before.
  • Data gathered from these infestations were compared with that from previously exposed (field-sensitized) horses and donkeys.

Findings

  • Tick-bite naïve horses developed a minimal level of resistance after two infestations. This was indicated by a notable decrease in the larval output and a trend towards less fully fed nymph weight during the third infestation.
  • Ticks feeding on field-sensitized horses mirrored biological performance seen in the third infestation on tick-bite naïve horses, but their average engorged nymph weight was substantially less than that of the first infestation from tick-bite naïve horses.

Observations on Donkeys

  • Donkeys displayed the strongest resistance to the ticks, with significantly lower engorged weights of all life stages of the tick and of the egg mass compared to the first infestation of tick-bite naïve horses.
  • The resistance of donkeys was also markedly higher than that of field-sensitized horses, as highlighted by significantly lower egg mass weights.

Conclusions

  • The results suggest that donkeys, unlike horses, maintain a potent resistance to Amblyomma cajennense ticks.
  • The implications these findings can have on vectoring of tick-borne diseases were also deliberated upon.

Overall, this study showcases the inherent differences in resistance to tick infestations between horses and donkeys. While horses can develop a measure of resistance over time, donkeys appear to display more natural, significant resistance to such infestations. Understanding such resistance can have impacts on managing tick-borne diseases that are vectored by these ticks.

Cite This Article

APA
Castagnolli KC, de Figueiredo LB, Santana DA, de Castro MB, Romano MA, Szabó MP. (2003). Acquired resistance of horses to Amblyomma cajennense (Fabricius, 1787) ticks. Vet Parasitol, 117(4), 271-283. https://doi.org/10.1016/j.vetpar.2003.09.004

Publication

Veterinary parasitology
ISSN: 0304-4017
NlmUniqueID: 7602745
Country: Netherlands
Language: English
Volume: 117
Issue: 4
Pages: 271-283

Researcher Affiliations

Castagnolli, Karina C
  • Universidade Estadual Paulista, Jaboticabal, SP, Brazil.
de Figueiredo, Luciano B
    Santana, Danilo A
      de Castro, Márcio B
        Romano, Marco A
          Szabó, Matias P J

            MeSH Terms

            • Animals
            • Equidae / immunology
            • Equidae / parasitology
            • Horse Diseases / immunology
            • Horse Diseases / parasitology
            • Horses
            • Host-Parasite Interactions
            • Immunity, Innate
            • Ixodidae / immunology
            • Nymph / growth & development
            • Nymph / physiology
            • Tick Infestations / immunology
            • Tick Infestations / parasitology
            • Tick Infestations / veterinary

            Citations

            This article has been cited 15 times.
            1. Costa SCL, de Souza Freitas J, Carvalho FS, Pereira MJS, Cordeiro MD, da Fonseca AH, Gomes Jusi MM, Machado RZ, Munhoz AD. Frequency and factors associated of potential zoonotic pathogens (Borrelia spp., Rickettsia spp., Leishmania spp., and Anaplasma phagocytophilum) in equids in the state of Bahia, Brazil. Parasit Vectors 2021 May 22;14(1):275.
              doi: 10.1186/s13071-021-04777-4pubmed: 34022939google scholar: lookup
            2. Ferreira LL, Sarria ALF, de Oliveira Filho JG, de Silva FO, Powers SJ, Caulfield JC, Pickett JA, Birkett MA, Borges LMF. Identification of a non-host semiochemical from tick-resistant donkeys (Equus asinus) against Amblyomma sculptum ticks. Ticks Tick Borne Dis 2019 Apr;10(3):621-627.
              doi: 10.1016/j.ttbdis.2019.02.006pubmed: 30799282google scholar: lookup
            3. Szabó MPJ, Martins MM, de Castro MB, Pacheco RC, Tolesano-Pascoli GV, Dos Santos KT, Martins TF, de Souza LGA, May-Junior JA, Yokosawa J, Labruna MB. Ticks (Acari: Ixodidae) in the Serra da Canastra National Park in Minas Gerais, Brazil: species, abundance, ecological and seasonal aspects with notes on rickettsial infection. Exp Appl Acarol 2018 Nov;76(3):381-397.
              doi: 10.1007/s10493-018-0300-9pubmed: 30317459google scholar: lookup
            4. Rodríguez-Mallon A. Developing Anti-tick Vaccines. Methods Mol Biol 2016;1404:243-259.
              doi: 10.1007/978-1-4939-3389-1_17pubmed: 27076303google scholar: lookup
            5. Ramos VN, Piovezan U, Franco AH, Rodrigues VS, Nava S, Szabó MP. Nellore cattle (Bos indicus) and ticks within the Brazilian Pantanal: ecological relationships. Exp Appl Acarol 2016 Feb;68(2):227-40.
              doi: 10.1007/s10493-015-9991-3pubmed: 26613758google scholar: lookup
            6. Carvalho-Costa TM, Mendes MT, da Silva MV, da Costa TA, Tiburcio MG, Anhê AC, Rodrigues V Jr, Oliveira CJ. Immunosuppressive effects of Amblyomma cajennense tick saliva on murine bone marrow-derived dendritic cells. Parasit Vectors 2015 Jan 14;8:22.
              doi: 10.1186/s13071-015-0634-7pubmed: 25586117google scholar: lookup
            7. Ramos Vdo N, Piovezan U, Franco AH, Osava CF, Herrera HM, Szabó MP. Feral pigs as hosts for Amblyomma sculptum (Acari: Ixodidae) populations in the Pantanal, Mato Grosso do Sul, Brazil. Exp Appl Acarol 2014 Nov;64(3):393-406.
              doi: 10.1007/s10493-014-9832-9pubmed: 25037743google scholar: lookup
            8. Beati L, Nava S, Burkman EJ, Barros-Battesti DM, Labruna MB, Guglielmone AA, Cáceres AG, Guzmán-Cornejo CM, León R, Durden LA, Faccini JL. Amblyomma cajennense (Fabricius, 1787) (Acari: Ixodidae), the Cayenne tick: phylogeography and evidence for allopatric speciation. BMC Evol Biol 2013 Dec 9;13:267.
              doi: 10.1186/1471-2148-13-267pubmed: 24320199google scholar: lookup
            9. Marufu MC, Dzama K, Chimonyo M. Cellular responses to Rhipicephalus microplus infestations in pre-sensitised cattle with differing phenotypes of infestation. Exp Appl Acarol 2014 Feb;62(2):241-52.
              doi: 10.1007/s10493-013-9723-5pubmed: 24057115google scholar: lookup
            10. Nunes PH, Bechara GH, Camargo Mathias MI. Secretory process of salivary glands of female Amblyomma cajennense (Acari: Ixodidae) ticks fed on resistant rabbits. Exp Appl Acarol 2011 Feb;53(2):179-87.
              doi: 10.1007/s10493-010-9388-2pubmed: 20711802google scholar: lookup
            11. Szabó MP, Pereira Lde F, Castro MB, Garcia MV, Sanches GS, Labruna MB. Biology and life cycle of Amblyomma incisum (Acari: Ixodidae). Exp Appl Acarol 2009 Jul;48(3):263-71.
              doi: 10.1007/s10493-008-9234-ypubmed: 19130270google scholar: lookup
            12. Szabó MP, Labruna MB, Castagnolli KC, Garcia MV, Pinter A, Veronez VA, Magalhães GM, Castro MB, Vogliotti A. Ticks (Acari: Ixodidae) parasitizing humans in an Atlantic rainforest reserve of Southeastern Brazil with notes on host suitability. Exp Appl Acarol 2006;39(3-4):339-46.
              doi: 10.1007/s10493-006-9013-6pubmed: 16900313google scholar: lookup
            13. Szabó MP, Castagnolli KC, Santana DA, de Castro MB, Romano MA. Amblyomma cajennense ticks induce immediate hypersensitivity in horses and donkeys. Exp Appl Acarol 2004;33(1-2):109-17.
              doi: 10.1023/b:appa.0000030016.33747.99pubmed: 15285143google scholar: lookup
            14. Prado Sousa AC, Durán-Prado M, Villar M, González-García A, Szabó MPJ, de la Fuente J. Tick saliva protein fraction inhibits breast cancer by decreasing cell viability and promoting apoptosis in vitro. PLoS One 2025;20(9):e0331779.
              doi: 10.1371/journal.pone.0331779pubmed: 40961088google scholar: lookup
            15. Lima VH, do Nascimento Pinto SM, Barreto LP, Sarria ALF, Mascarin GM, Fernandes ÉKK, Borges LMF. Repellent activity of the non-host semiochemical (E)-2-octenal against Amblyomma sculptum and Amblyomma dubitatum ticks under field conditions. Exp Appl Acarol 2024 Apr;92(3):423-437.
              doi: 10.1007/s10493-023-00880-6pubmed: 38411794google scholar: lookup
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