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Acute pancreatitis following granulosa cell tumor removal in a mare.

Abstract: Acute pancreatitis is a rare disease in horses and is often associated with gastrointestinal disorders. Accurate diagnosis is challenging due to the presence of nonspecific clinical signs. This case represents the first documentation of acute pancreatitis in a horse following surgery of the reproductive tract. La pancréatite aiguë est une maladie rare chez les chevaux et est souvent associée aux troubles gastro-intestinaux. Un diagnostic exact est difficile en raison de la présence de signes cliniques non spécifiques. Ce cas représente la première fois qu’une pancréatite aiguë est documentée chez un cheval après la chirurgie de l’appareil reproducteur.(Traduit par Isabelle Vallières).
Publication Date: 2015-10-21 PubMed ID: 26483579PubMed Central: PMC4572822
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Summary

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This research article discusses a unique case of acute pancreatitis observed in a horse after the removal of a granulosa cell tumor from its reproductive system.

Overview of the Research

  • The study analyzes a rarely documented disease in horses – acute pancreatitis, which is broadly associated with gastrointestinal disorders. Interestingly, this case relates the onset of acute pancreatitis to a surgical procedure, more specifically, the removal of a granulosa cell tumor – a type of ovarian tumor common in horses, from its reproductive tract.

Challenges in Diagnosis

  • The authors note that diagnosing acute pancreatitis in horses is often difficult due to the presence of nonspecific clinical signs. It indicates that it was a challenging medical scenario due to the lack of a specific symptomatology associated with it, making it hard for veterinarians to confirm an accurate diagnosis.

Uniqueness of the Case

  • This research is significant as it brings forth the first recorded instance of acute pancreatitis in a horse post-surgery on its reproductive system. This could potentially stimulate further studies into the links between surgical procedures and the occurrence of pancreatitis in equines.
  • The case could become a reference for future diagnoses relating to similar conditions and would aid the veterinary community to better understand the correlations and explore ways to prevent or treat such post-operative complications.

Post-operative and Anticipated Outcomes

  • The research doesn’t disclose the post-operative status of the horse or the subsequent prognosis. However, this information would be vital as it may determine how the veterinary community should approach similar cases in the future.

Cite This Article

APA
Gomez DE, Radtke CL, Russell LA, Lopez A, Wichtel MW. (2015). Acute pancreatitis following granulosa cell tumor removal in a mare. Can Vet J, 56(10), 1049-1052.

Publication

ISSN: 0008-5286
NlmUniqueID: 0004653
Country: Canada
Language: English
Volume: 56
Issue: 10
Pages: 1049-1052

Researcher Affiliations

Gomez, Diego E
  • Department of Health Management (Gomez, Radtke, Russell, Wichtel), Department of Pathology and Microbiology (Lopez), Atlantic Veterinary College, University of Prince Edward Island, 550 University Avenue, Charlottetown, Prince Edward Island C1A 4P3.
Radtke, Catherine L
  • Department of Health Management (Gomez, Radtke, Russell, Wichtel), Department of Pathology and Microbiology (Lopez), Atlantic Veterinary College, University of Prince Edward Island, 550 University Avenue, Charlottetown, Prince Edward Island C1A 4P3.
Russell, Lauren A
  • Department of Health Management (Gomez, Radtke, Russell, Wichtel), Department of Pathology and Microbiology (Lopez), Atlantic Veterinary College, University of Prince Edward Island, 550 University Avenue, Charlottetown, Prince Edward Island C1A 4P3.
Lopez, Alfonso
  • Department of Health Management (Gomez, Radtke, Russell, Wichtel), Department of Pathology and Microbiology (Lopez), Atlantic Veterinary College, University of Prince Edward Island, 550 University Avenue, Charlottetown, Prince Edward Island C1A 4P3.
Wichtel, Maureen W
  • Department of Health Management (Gomez, Radtke, Russell, Wichtel), Department of Pathology and Microbiology (Lopez), Atlantic Veterinary College, University of Prince Edward Island, 550 University Avenue, Charlottetown, Prince Edward Island C1A 4P3.

MeSH Terms

  • Animals
  • Female
  • Granulosa Cell Tumor / surgery
  • Granulosa Cell Tumor / veterinary
  • Horse Diseases / diagnosis
  • Horse Diseases / etiology
  • Horse Diseases / pathology
  • Horses
  • Ovarian Neoplasms / surgery
  • Ovarian Neoplasms / veterinary
  • Pancreatitis / etiology
  • Pancreatitis / veterinary

References

This article includes 32 references
  1. Davis JL. Pancreatitic diseases. In: Smith BP, editor. Large Animal Internal Medicine. 5th ed. St. Louis, Missouri: Mosby; 2015. p. 804.
  2. Yamout SZ, Nieto JE, Anderson J, De Cock HE, Vapniarsky N, Aleman M. Pathological evidence of pancreatitis in 43 horses (1986-2011).. Equine Vet J Suppl 2012 Dec;(43):45-50.
  3. Drazner F. Diseases of the pancreas. In: Jones B, Liska W, editors. Canine and Feline Gastroenterology. Philadelphia, Pennsylvania: WB Saunders; 1986. pp. 295–344.
  4. Cappell MS. Acute pancreatitis: etiology, clinical presentation, diagnosis, and therapy.. Med Clin North Am 2008 Jul;92(4):889-923, ix-x.
    pubmed: 18570947doi: 10.1016/j.mcna.2008.04.013google scholar: lookup
  5. Waitt LH, Cebra CK, Tornquist SJ, Löhr CV. Panniculitis in a horse with peripancreatitis and pancreatic fibrosis.. J Vet Diagn Invest 2006 Jul;18(4):405-8.
    pubmed: 16921885doi: 10.1177/104063870601800417google scholar: lookup
  6. Bakos Z, Krajcsovics L, Tóth J. Successful medical treatment of acute pancreatitis in a horse.. Vet Rec 2008 Jan 19;162(3):95-6.
    pubmed: 18204037doi: 10.1136/vr.162.3.95google scholar: lookup
  7. Lindberg DA. Acute pancreatitis and hypertriglyceridemia.. Gastroenterol Nurs 2009 Mar-Apr;32(2):75-82; quiz 83-4.
    pubmed: 19357469doi: 10.1097/sga.0b013e31819de3e0google scholar: lookup
  8. McClure J. Acute pancreatitis. In: Robinson NE, editor. Current Therapy in Equine Medicine. Philadelphia, Pennsylvania: WB Saunders; 1987. pp. 46–47.
  9. Frank B, Gottlieb K. Amylase normal, lipase elevated: is it pancreatitis? A case series and review of the literature.. Am J Gastroenterol 1999 Feb;94(2):463-9.
  10. Tennent-Brown BS. Interpreting lactate measurement in critically ill horses: diagnosis, treatment, and prognosis.. Compend Contin Educ Vet 2012 Jan;34(1):E2.
    pubmed: 22271469
  11. BLEDSOE JW. Fatal acute hemorrhagic pancreatitis following abdominal hysterectomy. Report of a case.. Am Pract Dig Treat 1962 Mar;13:186-90.
    pubmed: 13869954
  12. Baker RH. Acute necrotizing pancreatitis in a horse.. J Am Vet Med Assoc 1978 Feb 1;172(3):268-70.
    pubmed: 563859
  13. Dacre KJ, Pirie RS, Scudamore C, Prince DR. Hyperlipaemia and pancreatitis in pony with Cushing’s disease. Equine Vet Educ 2003;15:175–181.
  14. Hamir AN. Verminous pancreatitis in a horse.. Vet Rec 1987 Sep 26;121(13):301-2.
    pubmed: 3424573doi: 10.1136/vr.121.13.301google scholar: lookup
  15. Lilley CW, Beeman GM. Gastric dilation associated with acute necrotizing pancreatitis. Equine Pract 1981;3:8–15.
  16. Breider MA, Kiely RG, Edwards JF. Chronic eosinophilic pancreatitis and ulcerative colitis in a horse.. J Am Vet Med Assoc 1985 Apr 15;186(8):809-11.
    pubmed: 3997643
  17. Buote M. Cholangiohepatitis and pancreatitis secondary to severe gastroduodenal ulceration in a foal.. Can Vet J 2003 Sep;44(9):746-8.
    pmc: PMC340274pubmed: 14524632
  18. Taintor J, Sartin EA, Waldridge BM, Schumacher J. Acute pancreatitis in a 3-day-old foal.. J Vet Intern Med 2006 Jan-Feb;20(1):210-2.
  19. Ollivett TL, Divers TJ, Cushing T, Priest H, Dawson DR, Peters R, Stokol T. Acute pancreatitis in two five-day-old Appaloosa foals.. Equine Vet J Suppl 2012 Feb;(41):96-9.
  20. Higginson CM. Pancreatitis of the Horse.. Can J Comp Med (Gard) 1937 Oct;1(1):27-36.
    pmc: PMC1701832pubmed: 17647320
  21. Kawaguchi K, Church S, Slocombe RF. Acute necrotising pancreatitis following grain overload in a donkey.. Aust Vet J 2004 Oct;82(10):619-21.
  22. Fernández-del Castillo C, Harringer W, Warshaw AL, Vlahakes GJ, Koski G, Zaslavsky AM, Rattner DW. Risk factors for pancreatic cellular injury after cardiopulmonary bypass.. N Engl J Med 1991 Aug 8;325(6):382-7.
    pubmed: 1712076doi: 10.1056/nejm199108083250602google scholar: lookup
  23. Putzke HP. [Iatrogenic damages of the exocrine pancreas (author's transl)].. Dtsch Z Verdau Stoffwechselkr 1981;41(3):117-28.
    pubmed: 7261994
  24. Doyle DJ, Mark PW. Reflex bradycardia during surgery.. Can J Anaesth 1990 Mar;37(2):219-22.
    pubmed: 2088315doi: 10.1007/bf03005473google scholar: lookup
  25. Hirata N, Miyashita R, Maruyama D, Kawaguchi R, Shimizu H, Yamakage M. Heart rate variability during abdominal surgical manipulation under general and epidural anesthesia.. J Anesth 2012 Dec;26(6):900-4.
    pubmed: 22718015doi: 10.1007/s00540-012-1431-5google scholar: lookup
  26. Matters RF. TORSION OF OVARIAN CYST WITH BRADYCARDIA.. Br Med J 1931 Jun 13;1(3675):1022-3.
    pmc: PMC2314748pubmed: 20776224doi: 10.1136/bmj.1.3675.1022google scholar: lookup
  27. Pretorius RG, Matory WE Jr, LaFontaine D. Management of massive ovarian tumors.. Surg Gynecol Obstet 1989 Dec;169(6):532-6.
    pubmed: 2554517
  28. Bunch SE. The exocrine pancreas. In: Nelson RW, Couto CG, editors. Small Animal Internal Medicine. 3rd ed. St. Louis, Missouri: Mosby; 2003. p. 512.
  29. Lankisch PG, Dröge M, Gottesleben F. Drug induced acute pancreatitis: incidence and severity.. Gut 1995 Oct;37(4):565-7.
    pmc: PMC1382911pubmed: 7489946doi: 10.1136/gut.37.4.565google scholar: lookup
  30. Furr M, Robertson J. Two cases of equine pancreatic disease and a review of the literature. Equine Vet Edu 1992;4:55–58.
  31. Orsini JA, Donawick WJ. Surgical treatment of gastroduodenal obstruction in foals. Vet Surg 1986;15:2–13.
  32. Halangk W, Lerch MM. Early events in acute pancreatitis.. Clin Lab Med 2005 Mar;25(1):1-15.
    pubmed: 15749229doi: 10.1016/j.cll.2004.12.006google scholar: lookup

Citations

This article has been cited 1 times.
  1. Durst M, Graf TR, Graf R, Kron M, Arras M, Zechner D, Palme R, Talbot SR, Jirkof P. Analysis of Pain and Analgesia Protocols in Acute Cerulein-Induced Pancreatitis in Male C57BL/6 Mice. Front Physiol 2021;12:744638.
    doi: 10.3389/fphys.2021.744638pubmed: 34880773google scholar: lookup