FREE SHIPPING over $40
OVER 10000 FIVE-STAR REVIEWS
5% OFF ALL SUBSCRIPTIONS
100% HAPPINESS GUARANTEE
Analyze Diet
0
The Journal of veterinary medical science2013; 76(3); 467-470; doi: 10.1292/jvms.13-0417

Adenocarcinoma involving the tongue and the epiglottis in a horse.

Abstract: Tumors involving the oral cavity of the horse are uncommon. No cases of equine adenocarcinoma on the dorsum of the tongue have been reported in the literature. We report a case of adenocarcinoma located on the dorsum of the posterior one-third of the tongue in a 29-year-old gelding with severe dysphagia. Endoscopy revealed an epiglottis involvement, and histology was consistent with adenocarcinoma arising from minor salivary glands, which was associated with a severe fungal colonization of affected tissues. The goals of this report are to present an uncommon case of dorsum of the tongue-associated neoplasia and to highlight the association with atypical fungal colonization, to review the literature and to discuss possible clinical approach and prognosis.
Get Full Text
Publication Date: 2013-11-27 PubMed ID: 24284972PubMed Central: PMC4013378DOI: 10.1292/jvms.13-0417Google Scholar: Lookup
The Equine Research Bank provides access to a large database of publicly available scientific literature. Inclusion in the Research Bank does not imply endorsement of study methods or findings by Mad Barn.
LinkedInCopy
  • Case Reports
  • Journal Article

Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

The research document describes a rare case of adenocarcinoma, a type of cancer, on the top of the tongue and the epiglottis of a 29-year-old gelding (a male horse) and its connection to unusual fungal invasion.

Introduction to the Case

  • The document depicts a rare case of adenocarcinoma found on a horse’s tongue, specifically the dorsum (top) of its posterior one-third part.
  • Cancer on the oral cavity of a horse is an uncommon occurrence, and specifically, no cases of adenocarcinoma on the dorsum of the tongue have been documented prior to this report.
  • Apart from the tongue, endoscopy also revealed the involvement of the epiglottis, the flap at the base of the tongue that guards the entrance of the windpipe.

Research Findings

  • The histological investigation was indicative of cancer that had originated from minor salivary glands, a type of adenocarcinoma.
  • The researchers discovered an unusual instance of severe fungal colonization on the affected tissues. The link between the adenocarcinoma and fungal colonization is considered to be atypical.
  • This document emphasizes the co-occurrence of the rare tongue-associated neoplasia with the uncommon fungal infestation.

Purpose of the Report

  • The report aims to document this infrequent case of adenocarcinoma on the dorsum of the tongue, its association with rare fungal colonization, and the epiglottis involvement.
  • The authors hope that sharing this case might contribute to the existing literature on equine cancer, specifically those involving the oral cavity.
  • The report also invites discussions regarding the potential clinical approaches that could be taken for such cases and the associated prognosis.

Cite This Article

APA
Laus F, Rossi G, Paggi E, Bordicchia M, Fratini M, Tesei B. (2013). Adenocarcinoma involving the tongue and the epiglottis in a horse. J Vet Med Sci, 76(3), 467-470. https://doi.org/10.1292/jvms.13-0417

Publication

The Journal of veterinary medical science
ISSN: 1347-7439
NlmUniqueID: 9105360
Country: Japan
Language: English
Volume: 76
Issue: 3
Pages: 467-470

Researcher Affiliations

Laus, Fulvio
  • School of Veterinary Medical Sciences, University of Camerino, Via Circonvallazione 93-95, 62024, Matelica (MC) Italy.
Rossi, Giacomo
    Paggi, Emanuele
      Bordicchia, Matteo
        Fratini, Margherita
          Tesei, Beniamino

            MeSH Terms

            • Adenocarcinoma / pathology
            • Adenocarcinoma / veterinary
            • Animals
            • Endoscopy / veterinary
            • Epiglottis / pathology
            • Head and Neck Neoplasms / pathology
            • Head and Neck Neoplasms / veterinary
            • Histological Techniques / veterinary
            • Horse Diseases / drug therapy
            • Horse Diseases / pathology
            • Horses
            • Salivary Glands / microbiology
            • Salivary Glands / pathology
            • Tongue Neoplasms / pathology

            References

            This article includes 22 references
            1. Attner P, Du J, Näsman A, Hammarstedt L, Ramqvist T, Lindholm J, Marklund L, Dalianis T, Munck-Wikland E. Human papillomavirus and survival in patients with base of tongue cancer.. Int J Cancer 2011 Jun 15;128(12):2892-7.
              doi: 10.1002/ijc.25625pubmed: 20725995google scholar: lookup
            2. Biller HF, Lawson W, Baek SM. Total glossectomy. A technique of reconstruction eliminating laryngectomy.. Arch Otolaryngol 1983 Feb;109(2):69-73.
              doi: 10.1001/archotol.1983.00800160003001pubmed: 6849668google scholar: lookup
            3. Burgess HJ, Lockerbie BP, Czerwinski S, Scott M. Equine laryngeal rhinosporidiosis in western Canada.. J Vet Diagn Invest 2012 Jul;24(4):777-80.
              doi: 10.1177/1040638712445773pubmed: 22604769google scholar: lookup
            4. Castleman WL, Toplon DE, Clark CK, Heskett TW, Farina LL, Lynch TM, Bryant UK, Del Piero F, Murphy B, Edwards JF. Rhabdomyosarcoma in 8 horses.. Vet Pathol 2011 Nov;48(6):1144-50.
              doi: 10.1177/0300985810395785pubmed: 21262788google scholar: lookup
            5. Easley J, Dixon PM, Schumacher J. Equine Dentistry. 2011.
            6. Gerard MP. Oral cavity masses. Current Therapy in Equine Medicine 2009;pp 348–350.
            7. Hanson PD, Frisbie DD, Dubielzig RR, Markel MD. Rhabdomyosarcoma of the tongue in a horse.. J Am Vet Med Assoc 1993 Apr 15;202(8):1281-4.
              pubmed: 8496087
            8. Howie F, Munroe G, Thompson H, Murphy D. Palatine squamous cell carcinoma involving the maxillary sinus in two horses. Equine Vet. Edu. 1992;4:3–7.
              doi: 10.1111/j.2042-3292.1992.tb01537.xgoogle scholar: lookup
            9. Johnson PJ. Dermatologic tumors (excluding sarcoids).. Vet Clin North Am Equine Pract 1998 Dec;14(3):625-58, viii.
              pubmed: 9891728doi: 10.1016/s0749-0739(17)30190-6google scholar: lookup
            10. Jubb KVF, Kennedy P C, Palmer N. Pathology of Domestic Animals, Vol. 2. 1993.
            11. Knottenbelt DC, Pascoe RR. Diseases and Disorders of the Horse. 1994.
            12. Lim JH, Lim JY, Kim YM, Kim CS, Choi SJ, Yi HG, Choi WG, Lee MH. Primary diffuse large B cell lymphoma of the base of tongue.. J Cancer Res Ther 2012 Jan-Mar;8(1):135-7.
              doi: 10.4103/0973-1482.95195pubmed: 22531534google scholar: lookup
            13. Nollet H, Vercauteren G, Martens A, Vanschandevijl K, Schauvliege S, Gasthuys F, Ducatelle R, Deprez P. Laryngeal rhinosporidiosis in a Belgian warmblood horse.. Zoonoses Public Health 2008 Jun;55(5):274-8.
              doi: 10.1111/j.1863-2378.2008.01112.xpubmed: 18454748google scholar: lookup
            14. Rhind SM, Dixon PM. T cell-rich B cell lymphosarcoma in the tongue of a horse.. Vet Rec 1999 Nov 6;145(19):554-5.
              doi: 10.1136/vr.145.19.554pubmed: 10609574google scholar: lookup
            15. Rischin D. Oropharyngeal cancer, human papilloma virus, and clinical trials.. J Clin Oncol 2010 Jan 1;28(1):1-3.
              doi: 10.1200/JCO.2009.24.9045pubmed: 19917855google scholar: lookup
            16. Schuh JC. Squamous cell carcinoma of the oral, pharyngeal and nasal mucosa in the horse.. Vet Pathol 1986 Mar;23(2):205-7.
              doi: 10.1177/030098588602300217pubmed: 3962089google scholar: lookup
            17. Seeliger F, Hess O, Pröpsting MJ, Naim HY, Kleinschmidt S, Woehrmann T, Germann PG, Baumgärtner W. Confocal laser scanning analysis of an equine oral mast cell tumor with atypical expression of tyrosine kinase receptor C-KIT.. Vet Pathol 2007 Mar;44(2):225-8.
              doi: 10.1354/vp.44-2-225pubmed: 17317803google scholar: lookup
            18. Seikaly H, Rieger J, Wolfaardt J, Moysa G, Harris J, Jha N. Functional outcomes after primary oropharyngeal cancer resection and reconstruction with the radial forearm free flap.. Laryngoscope 2003 May;113(5):897-904.
              doi: 10.1097/00005537-200305000-00023pubmed: 12792330google scholar: lookup
            19. Strafuss AC. Squamous cell carcinoma in horses.. J Am Vet Med Assoc 1976 Jan 1;168(1):61-2.
              pubmed: 1245449
            20. Tseng WC, Chang SY, Chu PY, Tai SK, Wang YF, Shiao AS, Tsai TL. Management of base of tongue squamous cell carcinoma: experience with 85 patients in Taipei Veterans General Hospital.. J Chin Med Assoc 2011 May;74(5):220-5.
              doi: 10.1016/j.jcma.2011.03.007pubmed: 21550009google scholar: lookup
            21. Vashisht K, Rock RW, Summers BA. Multiple masses in a horse's tongue resulting from an atypical perineurial cell proliferative disorder.. Vet Pathol 2007 May;44(3):398-402.
              doi: 10.1354/vp.44-3-398pubmed: 17491087google scholar: lookup
            22. Wilson GJ, Anthony ND. Chondrosarcoma of the tongue of a horse.. Aust Vet J 2007 Apr;85(4):163-5.
              doi: 10.1111/j.1751-0813.2007.00130.xpubmed: 17397390google scholar: lookup

            Citations

            This article has been cited 1 times.
            1. Peretti JC, Dos Santos AB, Davi Dos Santos E, Machado TP, Pescador CA, Quillas LJA, Milani VM, Picetti TS, da Motta AC. Oral T-cell-rich large B-cell lymphoma in a horse. Vet Res Commun 2024 Dec;48(6):4067-4071.
              doi: 10.1007/s11259-024-10476-zpubmed: 39190130google scholar: lookup
            Subscribe to our newsletter
            Join 100,127 horse owners like you who receive our email updates on horse health and nutrition.