[Adenomatous hyperplasia of equine allantoic epithelium – a warning sign? – A case report].
Abstract: Adenomatous hyperplasia of the equine allantoic epithelium (EAAH) is an infrequently observed nodular or plaque-like change in the placenta of the mare which is presented as a case description. EAAH is most frequently diagnosed in cases of aborted fetuses and is associated with inflammatory changes of the placenta. Histologically, different degrees of EAAH may be distinguished; however, these are not associated with specific clinical signs, degree of inflammation, a particular pathogen, or the frequency of abortions. It is assumed that EAAH represents a secondary, reactive change and has per se no influence on the vitality of the fetus itself. The lesion, however, should be taken seriously and considered as a warning sign for possible previous subclinical infections, even in clinically normal foals. This in turn should prompt more detailed clinical examination and monitoring of the mare and foal. Die equine adenomatöse Allantoishyperplasie (EAAH) ist eine selten beobachtete noduläre oder flächige Veränderung der Plazenta des Pferdes, die anhand eines Falls vorgestellt wird. Die EAAH wird gehäuft bei abortierten Feten diagnostiziert und ist mit entzündlichen Veränderungen der Plazenta assoziiert. Entsprechend ihrer Ausbildung werden histologisch verschiedene Grade der EAAH unterschieden, doch sind diese weder mit einer bestimmten klinischen Symptomatik, dem Entzündungsgrad, einem spezifischen Erreger oder der Häufigkeit von Aborten assoziiert. Es wird davon ausgegangen, dass die EAAH eine sekundäre, reaktive Veränderung darstellt und selbst keinen Einfluss auf die Vitalität des equinen Fetus hat. Die Läsion sollte jedoch auch bei klinisch unauffälligen Fohlen als Warnsignal für mögliche vorausgegangene subklinische Infektionen ernst genommen werden und Anlass für eine genauere klinische Untersuchung und Überwachung von Stute und Fohlen geben.
© Georg Thieme Verlag KG Stuttgart · New York.
Publication Date: 2019-12-06 PubMed ID: 31810086DOI: 10.1055/a-1019-7454Google Scholar: Lookup
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Summary
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The article represents a case of Adenomatous hyperplasia of the equine allantoic epithelium (EAAH), an unusual nodular or plaque-like change in a mare’s placenta. The researchers propose that this condition may serve as an indicator of past subclinical infections, and therefore, meriting closer clinical monitoring of both mare and foal, despite EAAH itself having no effect on the foetus’s vitality.
Background of EAAH
- EAAH is a not so common condition visible as a nodular or plaque-like alteration in a mare’s placenta. It is most often found in cases of aborted fetuses and is linked with inflammatory changes of the placenta.
- The condition can present in various degrees, which can be distinguished histologically – through the study of the microscopic structure of tissues. However, the differing degrees are not linked to specific clinical signs, the degree of inflammation, a specific pathogen, or the frequency of abortions.
- The researchers hypothesize that EAAH is a secondary, reactive change, meaning it does not affect the vitality – or the capacity to live, grow, or develop – of the equine fetus itself.
Significance of the Case Report
- This case report suggests that despite its lack of direct influence on the fetus’s vitality, EAAH should be taken seriously. It can work as a warning sign for possible previous subclinical infections.
- Subclinical infections are those that do not produce noticeable symptoms but can still have significant health impacts.
- The presence of EAAH might, therefore, be a reason for conducting more detailed clinical examination and monitoring of the mare and foal, even if the foal appears clinically normal.
Implication of the Study
- Even though the research is based on a single case, the findings implicate the importance of careful observation and increased clinical scrutiny for horses, especially for mares and foals, even in the absence of overt symptoms.
- It emphasizes on better veterinary care and reinforces the fact that seemingly innocuous conditions like EAAH can be indicators of potential underlying health problems.
Cite This Article
APA
Hülskötter K, Aurich C, Köhne M, Baumgärtner W, Wohlsein P.
(2019).
[Adenomatous hyperplasia of equine allantoic epithelium – a warning sign? – A case report].
Tierarztl Prax Ausg G Grosstiere Nutztiere, 47(6), 391-396.
https://doi.org/10.1055/a-1019-7454 Publication
Researcher Affiliations
- Institut für Pathologie, Tierärztliche Hochschule Hannover.
- Zentrum für systemische Neurowissenschaften.
- Plattform Besamung und Embryotransfer, Veterinärmedizinische Universität Wien.
- Graf-Lehndorff-Institut für Pferdewissenschaften, Veterinärmedizinische Universität Wien, Neustadt (Dosse).
- Institut für Pathologie, Tierärztliche Hochschule Hannover.
- Zentrum für systemische Neurowissenschaften.
- Institut für Pathologie, Tierärztliche Hochschule Hannover.
MeSH Terms
- Adenoma / pathology
- Adenoma / veterinary
- Allantois / pathology
- Animals
- Diagnosis, Differential
- Epithelium / pathology
- Female
- Horse Diseases / pathology
- Horses
- Hyperplasia / pathology
- Hyperplasia / veterinary
- Pregnancy
Conflict of Interest Statement
Die Autoren bestätigen, dass kein Interessenkonflikt besteht.
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