Age- and Sex-Related Modifications of Hematology in Spanish Purebred Horse.
Abstract: The purpose of this study was to test the hypothesis that age and sex significantly modulate the changes in hematological parameters of physiologically healthy Spanish Purebred horse, establishing the reference values. Blood samples were obtained on a total of 159 horses (n = 77 males and n = 82 females), classified in four age groups: group A (1-2 years; n = 39), group B (>2-3 years; n = 38), group C (>3-4 years; n = 41), and group D (>4-7 years; n = 41). By means ADVIA 2020i, red blood cell (RBC), hemoglobin concentration (HB), packed cell volume, mean corpuscular volume (MCV), mean corpuscular hemoglobin (MCH), mean corpuscular hemoglobin concentration, platelets (PLTs), as well as total and differential white blood cells (WBCs) were determined. Total plasma protein was determined by spectrophotometry. Results obtained showed that sex had a limited influence on these parameters, being the HB higher in males and WBC higher in females (P = .047). Age caused a reduction in RBC, with a compensatory increase of MCV and MCH, decrease in WBC, PLT, lymphocytes (LYMPs), as well as an increase of N/L ratio (P = .047). Interactions between age and sex showed higher RBC in males than in females of the group B, and higher HB and WBC in males than in females of the group D. According to hematological data, Spanish Purebred horse was classified as a warm- or cold-blooded horse. Decline of RBC, WBC, and PLT parameters is a natural condition of horse with the advance of age, indicating a decrease of the narrow bone response.
Copyright © 2020 Elsevier Inc. All rights reserved.
Publication Date: 2020-08-07 PubMed ID: 32972677DOI: 10.1016/j.jevs.2020.103219Google Scholar: Lookup
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- Journal Article
Summary
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The research article explores the impact of age and sex on various hematological parameters in Spanish purebred horses, highlighting that both factors significantly affect these parameters, thereby establishing reference values.
Research Overview
- The study aimed to determine the influence of age and sex on changes in the hematological parameters of healthy Spanish Purebred horses, intending to set the reference values.
- The researchers examined blood samples taken from 159 horses (77 males and 82 females), which were divided into four age groups: A (1-2 years), B (over 2 to 3 years), C (over 3 to 4 years), and D (over 4 to 7 years).
- Various parameters including red blood cell count (RBC), Hemoglobin concentration (HB), Mean Corpuscular Volume (MCV), Mean Corpuscular Hemoglobin (MCH), platelet count (PLTs), total and differential white blood cell count (WBCs), and total plasma protein were analyzed using the ADVIA 2020i system and spectrophotometry.
Research Findings
- Results revealed that sex had a marginal impact on these parameters, with HB being higher in males and WBCs being higher in females (P = .047).
- The factor of age resulted in a decrease in RBCs, accompanied by a compensatory increase in MCV and MCH, a decrease in WBCs, PLTs, and lymphocytes (LYMPs), and an increase in the N/L ratio (P = .047).
- The interaction between age and sex indicated that males in group B had higher RBCs than females and males in group D had higher HB and WBCs than females.
- The hematological data classified Spanish Purebred horse as a warm- or cold-blooded horse.
Conclusions
- The decrease in RBCs, WBCs, and PLTs parameters with age is a natural process, indicating a decrease in the marrow bone response. This finding suggests that age and sex need to be considered in the interpretation of routine hematological analysis in Spanish purebred horses.
Cite This Article
APA
Satué K, Hernández Á, Lorente C, Fazio E, Medica P.
(2020).
Age- and Sex-Related Modifications of Hematology in Spanish Purebred Horse.
J Equine Vet Sci, 93, 103219.
https://doi.org/10.1016/j.jevs.2020.103219 Publication
Researcher Affiliations
- Department of Animal Medicine and Surgery, Faculty of Veterinary Medicine, Cardenal Herrera University, Valencia, Spain. Electronic address: ksatue@uch.ceu.es.
- Department of Animal Medicine and Surgery, Faculty of Veterinary Medicine, Cardenal Herrera University, Valencia, Spain.
- Private Clinician, Diplomate Dermatology, Adervet Clinic, Madrid, Spain.
- Department of Veterinary Sciences, Veterinary Physiology Unit, Messina University, Messina, Italy.
- Department of Veterinary Sciences, Veterinary Physiology Unit, Messina University, Messina, Italy.
MeSH Terms
- Animals
- Erythrocyte Indices / veterinary
- Female
- Hematocrit / veterinary
- Hematologic Tests / veterinary
- Hematology
- Horses
- Leukocyte Count / veterinary
- Male
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