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Equine veterinary journal. Supplement2011; (38); 220-227; doi: 10.1111/j.2042-3306.2010.00259.x

Age related decreases in thermoregulation and cardiovascular function in horses.

Abstract: Older horses have an increased risk of hyperthermia due to impaired cardiovascular function. While many studies have investigated thermoregulation in horses during exercise, none have investigated the effects of ageing. Objective: To test the hypothesis that there is a difference in thermoregulation during exercise and plasma volume (PV) in young and old horses. Methods: Study 1: 6 young (Y, 7.7 ± 0.5 years) and 5 old (O, 26.0 ± 0.8 years) unfit Standardbred mares (507 ± 11 kg, mean ± s.e.) ran on a treadmill (6% grade, velocity calculated to generate a work rate of 1625 watts) until core temperature reached 40 °C. Core (CT), skin (ST), rectal temperature (RT) and heart rate (HR) were measured every min until 10 min post exertion. Packed cell volume (HCT), lactate (LA) and plasma protein (TP) were measured in blood samples collected before, at 40 °C and every 5 min until 10 min post exercise. Sweat loss was estimated using bodyweight. Study 2: Plasma volume was measured in 26 young (8.2 ± 0.7 years) and 8 old (26.6 ± 0.7 years) Standardbred mares (515 ± 12 kg) using Evans Blue dye. Pre-exercise blood (rBV) and red cell (rRCV) volumes were calculated using PV and HCT. Data analysis utilised repeated measures ANOVA and t tests and data are expressed as mean ± s.e. Results: Old horses reached 40 °C faster (998 ± 113 vs. 1925 ± 259 s; P < 0.05) with a greater HR at 40 °C (184 ± 6 vs. 140 ± 5 beats/min; P < 0.05) and greater sweat losses (P 0.05) post exercise. Age did not alter (P > 0.05) CT, ST, RT, LA, HCT or TP. Plasma volume was greater in Y vs. O horses (P < 0.05, 28.5 ± 1.4 vs. 24.1 ± 1.6 l) as was rBV (41.3 ± 2.0 vs. 35.3 ± 2.3 l) and rRCV (13.3 ± 0.6 vs. 11.1 ± 0.8 l). Conclusions: Ageing compromises the ability to handle the combined demand of exercise and thermoregulation in part due to decreased absolute pre-exercise PV.
Publication Date: 2011-05-27 PubMed ID: 21059010DOI: 10.1111/j.2042-3306.2010.00259.xGoogle Scholar: Lookup
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  • Journal Article
  • Research Support
  • Non-U.S. Gov't

Summary

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The research reveals that older horses might be more prone to heat-related challenges, possibly due to compromised cardiovascular functions and reduced plasma volume, which seem to affect their ability to balance exercise and body temperature regulation.

Methodology

The study was divided into two parts.

  • In the first part, 11 Standardbred mares, 6 young (average 7.7 years) and 5 older ones (average 26 years), were run on a treadmill set with specifications to ensure an even work rate of 1625 watts until their core temperature hit 40 degrees Celsius. Throughout the process and up to 10 minutes after stopping, their core, skin, and rectal temperature, along with heart rates, were recorded per minute. The subjects’ blood samples were collected pre and post exercise at 40 degrees Celsius and every 5 minutes up to 10 minutes to measure packed cell volume, lactate, and plasma protein. Sweat loss was estimated via body weight.
  • In the second part of the study, plasma volume was gauged in 26 young (average 8.2 years) and 8 older horses (average 26.6 years) using Evans Blue dye. Red cell volume and blood volume before exercise were calculated with the help of these plasma volume readings and packed cell volume.

Results

Research findings highlighted several key differences between young and older horses.

  • Older horses quicker reached preferred core temperature (40 degrees Celsius), had a higher heart rate when they hit that temperature, and had higher sweat losses—all of which imply they exerted themselves more.
  • Heart rates after exercise were not significantly different between young and old horses indicating similar recovery times.
  • There were no significant age-related differences in core, skin, and rectal temperatures before and after exercise, lactate levels, packed cell volume, or plasma protein, which means that age did not affect these particular variables.
  • They found higher plasma volume and pre-exercise blood and red cell volume in younger horses as compared to older ones.

Conclusion

Merging the findings from both studies showed that ageing could reduce a horse’s ability to manage simultaneous demands of exercise and body temperature regulation, partly due to a decrease in pre-exercise plasma volume. This understanding could guide the management of physical exertion in older horses.

Cite This Article

APA
McKeever KH, Eaton TL, Geiser S, Kearns CF, Lehnhard RA. (2011). Age related decreases in thermoregulation and cardiovascular function in horses. Equine Vet J Suppl(38), 220-227. https://doi.org/10.1111/j.2042-3306.2010.00259.x

Publication

NlmUniqueID: 9614088
Country: United States
Language: English
Issue: 38
Pages: 220-227

Researcher Affiliations

McKeever, K H
  • Equine Science Center, Department of Animal Sciences, Rutgers - the State University of New Jersey, New Brunswick, USA. mckeever@aesop.rutgers.edu
Eaton, T L
    Geiser, S
      Kearns, C F
        Lehnhard, R A

          MeSH Terms

          • Aging / physiology
          • Animals
          • Blood Proteins / physiology
          • Body Temperature Regulation / physiology
          • Dehydration
          • Female
          • Heart Rate / physiology
          • Hematocrit
          • Horses / physiology
          • Lactic Acid / blood
          • Physical Conditioning, Animal / physiology
          • Plasma Volume
          • Time Factors

          Citations

          This article has been cited 11 times.
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