An outbreak of Lawsonia intracellularis infection in a standardbred herd in Ontario.
Abstract: An outbreak of protein-losing enteropathy associated with Lawsonia intracelluaris infection was diagnosed in 6 standardbred foals from a farm in Ontario. Wildlife exposure may have been involved in the perpetuation of disease in this outbreak. The clinical presentation, treatment, outcomes, and pathological findings are described. Éclosion d’infections à Lawsonia intracellularis dans un troupeau de Standardbred en Ontario. Une éclosion d’entéropathies exsudatives associée à une infection à Lawsonia intracellularis a été diagnostiquée chez 6 poulains Standardbred d’une ferme de l’Ontario. Un contact avec la faune pourrait être impliqué dans la perpétuation de la maladie lors de cette éclosion. La présentation clinique, le traitement, l’évolution et les résultats pathologiques sont décrits. (Traduit par Docteur André Blouin)
Publication Date: 2007-10-31 PubMed ID: 17966333PubMed Central: PMC1950111
The Equine Research Bank provides access to a large database of publicly available scientific literature. Inclusion in the Research Bank does not imply endorsement of study methods or findings by Mad Barn.
- Case Reports
- Journal Article
Summary
This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.
The research investigates an outbreak of Lawsonia intracellularis infection that led to protein-losing enteropathy in six Standardbred foals on a farm in Ontario, exploring the potential role of environmental factors such as wildlife exposure and providing an overview of the clinical treatment and outcomes.
Introduction to Lawsonia intracellularis Infection
- Lawsonia intracellularis is a bacterium that can cause a disease in horses known as proliferative enteropathy, characterized by thickening of the intestinal lining.
- This infection can lead to protein-losing enteropathy, a disorder where protein is lost from the gut into the intestines, causing low protein levels in the blood.
- The disease can cause diarrhoea, weight loss, colic, and swelling in young horses.
Outbreak in Ontario
- The research centers on an outbreak of this infection in six Standardbred foals on a farm in Ontario.
- The researchers suggest that exposure to wildlife might be a contributing factor to the outbreak, perhaps by serving as vectors for the bacteria.
- The paper gives an account of the clinical presentation of the disease, describing symptoms and indicators observed in the affected foals.
Treatment and Outcomes
- The researchers describe the treatment administered to horses to manage the disease, though the paper does not explicitly state what the treatment was.
- The outcomes after the treatment are also detailed, offering insights into the recovery and survival rates among the affected foals.
Contribution to Veterinary Science
- This study provides veterinarians with deeper insights into the presentation, management, and outcomes of Lawsonia intracellularis infection, potentially informing more effective treatments and interventions in future.
- It also highlights the potential role of environmental risk factors, thereby urging the need to consider these in strategies to prevent disease outbreak and spread.
Cite This Article
APA
McGurrin MK, Vengust M, Arroyo LG, Baird JD.
(2007).
An outbreak of Lawsonia intracellularis infection in a standardbred herd in Ontario.
Can Vet J, 48(9), 927-930.
Publication
Researcher Affiliations
- Department of Clinical Studies, Ontario Veterinary College, University of Guelph, Guelph, Ontario N1G 2W1. mcgurrin@uoguelph.ca
MeSH Terms
- Animals
- Animals, Wild / microbiology
- Anti-Bacterial Agents / therapeutic use
- Desulfovibrionaceae Infections / drug therapy
- Desulfovibrionaceae Infections / epidemiology
- Desulfovibrionaceae Infections / transmission
- Desulfovibrionaceae Infections / veterinary
- Disease Outbreaks / veterinary
- Fatal Outcome
- Female
- Horse Diseases / drug therapy
- Horse Diseases / epidemiology
- Horse Diseases / transmission
- Horses
- Lawsonia Bacteria / drug effects
- Lawsonia Bacteria / isolation & purification
- Male
- Ontario / epidemiology
- Treatment Outcome
References
This article includes 20 references
- Smith DG, Lawson GH. Lawsonia intracellularis: Getting inside the pathogenesis of proliferative enteropathy.. Vet Microbiol 2001;82:331–345.
- Lawson GH, Gebhart CJ. Proliferative enteropathy.. J Comp Pathol 2000;122:77–100.
- Duhamel GE, Klein EC, Elder RO, Gebhart CJ. Subclinical proliferative enteropathy in sentinel rabbits associated with Lawsonia intracellularis.. Vet Pathol 1998;35:300–303.
- Al-Ghamdi GM. Characterization of proliferative enteropathy in horses [PhD dissertation] Minnesota.. University of Minnesota 2003.
- Schumacher J, Schumacher J, Rolsma M, Brock KV, Gebhart CJ. Surgical and medical treatment of an Arabian filly with proliferative enteropathy caused by Lawsonia intracellularis.. J Vet Intern Med 2000;14:630–632.
- Lavoie JP, Drolet R, Parsons D. Equine proliferative enteropathy: A cause of weight loss, colic, diarrhoea and hypoproteinaemia in foals on three breeding farms in Canada.. Equine Vet J 2000;32:418–425.
- Brees DJ, Sondhoff AH, Kluge JP, Andreasen CB, Brown CM. Lawsonia intracellularis-like organism infection in a miniature foal.. J Am Vet Med Assoc 1999;215:511–514.
- Frank N, Fishman CE, Gebhart CJ, Levy M. Lawsonia intracellularis proliferative enteropathy in a weanling foal.. Equine Vet J 1998;30:549–552.
- Williams NM, Harrison LR, Gebhart CJ. Proliferative enteropathy in a foal caused by Lawsonia intracellularis-like bacterium.. J Vet Diagn Invest 1996;8:254–256.
- Deprez P, Chiers C, Gebhart CJ. Lawsonia intracellularis in a 12-month-old colt in Belgium.. Vet Rec 2005;157:774–776.
- Wuersch K, Huessy D, Koch C, Oevermann A. Lawsonia intracellularis proliferative enteropathy in a filly.. J Vet Med A Physiol Pathol Clin Med 2006;53:17–21.
- McClintock SA, Collins AM. Lawsonia intracellularis proliferative enter-opathy in a weanling foal in Australia.. Aust Vet J 2004;82:750–752.
- Guedes RM, Gebhart CJ. Onset and duration of fecal shedding, cell-mediated and humoral immune responses in pigs after challenge with a pathogenic isolate or attenuated vaccine strain of Lawsonia intracellularis.. Vet Microbiol 2003;91:135–145.
- Collins AM, Love RJ, Jasni S, McOrist S. Attempted infection of mice, rats and chickens by porcine strains of Lawsonia intracellularis.. Aust Vet J 1999;77:120–122.
- Suh DK, Lym SK, Bae YC. Detection of Lawsonia intracellularis in diagnostic specimens by one-step PCR.. J Vet Sci 2000;1:33–37.
- Huerta B, Arenas A, Carrasco L. Comparison of diagnostic techniques for porcine proliferative enteropathy (Lawsonia intracellularis infection). J Comp Pathol 2003;129:179–185.
- Hagen B, Bilkei G. Seroprevalence of Lawsonia intracellularis in large pig production units.. Acta Vet Hung 2003;51:165–170.
- Driemeier D, Faccini GS, de Oliveira RT. Silver staining combined with alcian blue and hematoxylin-eosin for the detection of Lawsonia intracelullaris in swine proliferative enteropathy.. Acta Histochem 2002;104:285–287.
- Guedes RM, Gebhart CJ, Winkelman NL. Comparison of different methods for diagnosis of porcine proliferative enteropathy.. Can J Vet Res 2002;66:99–107.
- Cooper DM, Swanson DL, Gebhart CJ. Diagnosis of proliferative enteritis in frozen and formalin-fixed, paraffin-embedded tissues from a hamster, horse, deer and ostrich using a Lawsonia intracellularis-specific multiplex PCR assay.. Vet Microbiol 1997;54:47–62.
Use Nutrition Calculator
Check if your horse's diet meets their nutrition requirements with our easy-to-use tool Check your horse's diet with our easy-to-use tool
Talk to a Nutritionist
Discuss your horse's feeding plan with our experts over a free phone consultation Discuss your horse's diet over a phone consultation
Submit Diet Evaluation
Get a customized feeding plan for your horse formulated by our equine nutritionists Get a custom feeding plan formulated by our nutritionists