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Journal of advanced veterinary and animal research2021; 8(1); 173-184; doi: 10.5455/javar.2021.h500

Antioxidants in assisted reproductive technologies: An overview on dog, cat, and horse.

Abstract: Assisted reproductive technologies (ARTs) are widely used as a tool to improve reproductive performance in both humans and animals. In particular, in the veterinary field, ARTs are used to improve animal genetics, recover endangered animals, and produce offspring in the event of subfertility or infertility in males or females. However, the use of ARTs did not improve the fertilization rate in some animals due to various factors such as the difficulty in reproducing an anatomical and humoral substrate typical of the natural condition or due to the increase in catabolites and their difficult elimination. The in vitro environment allows the production and increase in the concentration of substances, including reactive oxygen species (ROS), which could be harmful to gametes. If produced in high concentration, the ROS becomes deleterious, both in vitro and in vivo systems. It has been seen that the use of antioxidants can help neutralize or counteract the production of ROS. The present study aims to report the latest findings regarding the use of antioxidants in ARTs of some domestic species, such as dogs, cats, and horses, compared to other animal species, such as cattle, in which ARTs have instead developed more widely.
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Publication Date: 2021-03-11 PubMed ID: 33860028PubMed Central: PMC8043350DOI: 10.5455/javar.2021.h500Google Scholar: Lookup
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Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

This research study explores the role of antioxidants in enhancing the effect of Assisted Reproductive Technologies (ARTs) in domestic animals like dogs, cats, and horses. It specifically investigates how antioxidants counteract harmful reactive oxygen species (ROS) influences on the reproductive systems of these animals.

Assisted Reproductive Technologies in Veterinary Field

  • This study primarily deals with assisted reproductive technologies (ARTs), techniques used to enhance reproductive performance. In the veterinary field, these are used to improve animal genetics, recover endangered species, and produce offspring in the event of subfertility or infertility in male or female animals.
  • Despite their extensive use, ARTs have not always improved the fertilization rate across all animals due to a variety of circumstances, including the challenge of replicating natural anatomical and humoral substrates, and the accumulation of hard-to-eliminate catabolites.

The Role of Reactive Oxygen Species

  • The research highlights the role of reactive oxygen species (ROS), substances produced during biological processes. These, when produced in high concentrations, can be harmful to an animal’s gametes – the reproductive cells.
  • Both endogenous (arising from normal metabolic processes) and exogenous (arising from outside factors such as pollution or radiation) ROS can lead to harmful effects on gametes, affecting their capacity to function efficiently.

The Impact of Antioxidants

  • The study examines how antioxidants can potentially neutralize or counteract the detrimental impact of ROS on gametes, thus potentially enhancing the effectiveness of ARTs.
  • Antioxidants have the ability to interact with ROS, preventing them from causing damage. This is crucial as the negative impact of ROS can cause difficulties in the effectiveness of ARTs.

Focus on Domestic Animals

  • The research primarily focuses on the use of antioxidants in ARTs for domestic animals such as dogs, cats, and horses.
  • These species were chosen for comparison to other animal species like cattle, where ARTs have developed more broadly and effectively. The research aims to use this comparison to further the development and effectiveness of ARTs in these less explored animals.

Cite This Article

APA
Ciani F, Maruccio L, Cocchia N, d'Angelo D, Carotenuto D, Avallone L, Namagerdi AA, Tafuri S. (2021). Antioxidants in assisted reproductive technologies: An overview on dog, cat, and horse. J Adv Vet Anim Res, 8(1), 173-184. https://doi.org/10.5455/javar.2021.h500

Publication

Journal of advanced veterinary and animal research
ISSN: 2311-7710
NlmUniqueID: 101647585
Country: Bangladesh
Language: English
Volume: 8
Issue: 1
Pages: 173-184

Researcher Affiliations

Ciani, Francesca
  • Department of Veterinary Medicine and Animal Production, University of Naples Federico II, Naples, Italy.
  • These authors contributed equally.
Maruccio, Lucianna
  • Department of Veterinary Medicine and Animal Production, University of Naples Federico II, Naples, Italy.
  • These authors contributed equally.
Cocchia, Natascia
  • Department of Veterinary Medicine and Animal Production, University of Naples Federico II, Naples, Italy.
d'Angelo, Danila
  • Department of Veterinary Medicine and Animal Production, University of Naples Federico II, Naples, Italy.
Carotenuto, Domenico
  • UNMSM, Universidad Nacional Mayor San Marcos, Lima, Peru.
Avallone, Luigi
  • Department of Veterinary Medicine and Animal Production, University of Naples Federico II, Naples, Italy.
Namagerdi, Asadoor Amirkhani
  • Department of Veterinary Medicine and Animal Production, University of Naples Federico II, Naples, Italy.
Tafuri, Simona
  • Department of Veterinary Medicine and Animal Production, University of Naples Federico II, Naples, Italy.

Conflict of Interest Statement

The authors declare no conflict of interest.

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