Application of an electrocardiography device (iECG) for heart rhythm analysis after exercise in Thoroughbred horses.
Abstract: AliveCor is a smartphone electrocardiography device (iECG) providing automated heart rate (HR) and rhythm determination. Atrial fibrillation (AF) in horses often is paroxysmal and rapid ECG acquisition is needed for diagnostic confirmation. iECGs were collected post-race from 15 horses with AF and 64 horses in sinus rhythm (SR). Results of manual assessment were compared to 3 commercial algorithms for HR and rhythm. Agreement between manually derived HR (HRM ) and HR derived by the AliveECG Vet (HRVET ) and Kardia version-1 (KV1 HR) and Kardia advanced (KADV HR) algorithms was quantified by the Bland-Altman limits of agreement test. Agreement between manual rhythm classification and KV1 and KADV algorithms for AF and SR was calculated by the Kappa statistical coefficient. The agreement (bias, 95% limits), between HRM and HRVET was 7.1 BPM (-29 to 43) in AF and -4.2 BPM (-38 to 30) in SR, between HRM and KV1 HR, was -0.3 BPM (-31 to 30) in AF and 0.2 BPM (-3 to 4) in SR, and between HRM and KADV HR was 7.0 BPM (-29 to 43) in AF and 0.2 BPM (-3.9 to 4.2) in SR. Agreement between manual rhythm classification and KV1 was 0.36 (0.13-0.59), and KADV was 0.84 (0.68-0.99). Sensitivity and specificity for identification of AF and SR of the KV1 algorithm were 60, 100% and 83, 100%, respectively, and of KADV was 87, 100% and 93, 100% respectively. The Kardia algorithms improved precision for HR determination in SR but not AF. The advanced algorithm accurately distinguished between AF and SR. The iECG is suitable for recording episodes of AF following exercise.
© 2021 Australian Veterinary Association.
Publication Date: 2021-12-02 PubMed ID: 34859419DOI: 10.1111/avj.13137Google Scholar: Lookup
The Equine Research Bank provides access to a large database of publicly available scientific literature. Inclusion in the Research Bank does not imply endorsement of study methods or findings by Mad Barn.
- Journal Article
- Athletic Horses
- Athletic Performance
- Cardiac Arrhythmias
- Cardiovascular Health
- Clinical Findings
- Clinical Study
- Diagnosis
- Diagnostic Technique
- Disease Diagnosis
- Electrocardiography
- Equine Health
- Exercise
- Exercise Physiology
- Heart
- Heart Rate
- Horse Racing
- Horses
- Technology
- Thoroughbreds
- Veterinary Medicine
- Veterinary Research
Summary
This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.
The research investigates the efficacy of a smartphone electrocardiography device, AliveCor, in identifying heart rate and rhythm after exercise in Thoroughbred horses. The study particularly focuses on cases of atrial fibrillation (AF) and sinus rhythm (SR), assessing the performance of AliveCor and its algorithms against manual assessments.
Introduction to the Research
- The study presents a comparison between manual assessment of heart rate and rhythm in Thoroughbred horses and the measurements derived from a smartphone electrocardiography device called AliveCor.
- The study places special emphasis on two conditions – atrial fibrillation (AF) and sinus rhythm (SR). AF is often sporadic and requires quick ECG acquisition for accurate diagnosis.
- AliveCor uses automated means to record heart rate and rhythm, offering a potentially more immediate and convenient solution for detecting these conditions post-exercise.
Methodology
- iECGs were collected from a sample of 15 horses with AF and 64 horses in SR after they had completed a race.
- The manual data was contrasted with the results produced by AliveCor, specifically three commercial algorithms for heart rate and rhythm which were named AliveECG Vet, Kardia version-1, and Kardia advanced.
- To determine the level of agreement between AliveCor’s measurements and the manual readings, the researchers used the Bland-Altman limits of agreement test.
- The Kappa statistical coefficient was used to calculate agreement between the manual assessment and the Kardia algorithms in classifying the rhythm as AF or SR.
Findings
- The results showed varying degrees of agreement between the heart rates determined by the manual assessments and those derived by the AliveECG Vet, Kardia version-1, and Kardia advanced algorithms.
- It was found that the Kardia algorithms improved the precision of heart rate determination in horses in a sinus rhythm, but didn’t achieve the same accuracy for cases of AF.
- The advanced Kardia algorithm showed accurate differentiation between AF and SR.
- The data suggests that the iECG, equipped with its advanced algorithm, is fit for recording episodes of AF in horses after exercise.
Cite This Article
APA
Nath LC, Forbes G, Elliott AD, Tomren V, Ryan A, Franklin SH.
(2021).
Application of an electrocardiography device (iECG) for heart rhythm analysis after exercise in Thoroughbred horses.
Aust Vet J, 100(3), 114-120.
https://doi.org/10.1111/avj.13137 Publication
Researcher Affiliations
- University of Adelaide, Roseworthy, South Australia, Australia.
- Racing Victoria, Flemington, Victoria, Australia.
- University of Adelaide, Adelaide, South Australia, Australia.
- Racing Victoria, Flemington, Victoria, Australia.
- University of Adelaide, Roseworthy, South Australia, Australia.
- University of Adelaide, Roseworthy, South Australia, Australia.
MeSH Terms
- Algorithms
- Animals
- Atrial Fibrillation / diagnosis
- Atrial Fibrillation / veterinary
- Electrocardiography / methods
- Electrocardiography / veterinary
- Heart Rate / physiology
- Horse Diseases / diagnosis
- Horses
- Sensitivity and Specificity
Grant Funding
- Racing Victoria
References
This article includes 32 references
- Slack J, Boston RC, Soma LR. Occurrence of cardiac arrhythmias in Standardbred racehorses.. Equine Vet J 2015;47:398-404.
- Holmes JR. Cardiac arrhythmias on the racecourse.. Equine Exerc Physiol 1987;2:781-785.
- Ohmura H, Hiraga A, Takahashi T. Risk factors for atrial fibrillation during racing in slow-finishing horses.. J Am Vet Med Assoc 2003;223:84-88.
- Williams R, Harkins L, Hammond C. Racehorse injuries, clinical problems and fatalities recorded on British racecourses from flat racing and National Hunt racing during 1996, 1997 and 1998.. Equine Vet Jo 2001;33:478-486.
- Nath LC, Elliott AD, Weir J. Incidence, recurrence, and outcome of postrace atrial fibrillation in Thoroughbred horses.. J Vet Intern Med 2021;35:1111-1120.
- Rosanowski S, Chang Y, Stirk A. Descriptive epidemiology of veterinary events in flat racing Thoroughbreds in Great Britain (2000 to 2013).. Equine Vet J 2017;49:275-281.
- Physick-Sheard PW, McGurrin MK. Ventricular arrhythmias during race recovery in Standardbred racehorses and associations with autonomic activity.. J Vet Inter Med/Am Coll Vet Intern Med 2010;24:1158-1166.
- Naylor JM, Yademuk LM, Pharr JW. An assessment of the ability of diplomates, practitioners, and students to describe and interpret recordings of heart murmurs and arrhythmia.. J Vet Intern Med 2001;15:507-515.
- Verheyen T, Decloedt A, van der Vekens N. Ventricular response during lungeing exercise in horses with lone atrial fibrillation.. Equine Vet J 2013;45:309-314.
- Heliczer N, Mitchell K, Lorello O. Atrial fibrillation management in a breeding stallion.. J Vet Cardiol 2017;19:299-307.
- Buhl R, Carstensen H, Hesselkilde EZ. Effect of induced chronic atrial fibrillation on exercise performance in Standardbred trotters.. J Vet Intern Med/Am Coll Vet Intern Med 2018;32:1410-1419.
- Reef VB, Bonagura J, Buhl R. Recommendations for management of equine athletes with cardiovascular abnormalities.. J Vet Intern Med/Am Coll Vet Intern Med 2014;28:749-761.
- de Solis CN. Ventricular arrhythmias in horses: diagnosis, prognosis and treatment.. Vet J 2020;105476:105476.
- Orchard J, Lowres N, Freedman SB. Screening for atrial fibrillation during influenza vaccinations by primary care nurses using a smartphone electrocardiograph (iECG): a feasibility study.. Eur J Prev Cardiol 2016;23:13-20.
- Wegner FK, Kochhäuser S, Ellermann C. Prospective blinded evaluation of the smartphone-based AliveCor Kardia ECG monitor for atrial fibrillation detection: the PEAK-AF study.. Eur J Intern Med 2020;73:72-75.
- William AD, Kanbour M, Callahan T. Assessing the accuracy of an automated atrial fibrillation detection algorithm using smartphone technology: the iREAD study.. Heart Rhythm 2018;15:1561-1565.
- Hermans A, Gawalko M, Pluymaekers N. Detection of atrial fibrillation recurrences after ablation: Long-term intermittent versus short continuous heart rhythm monitoring.. Eur Heart J 2020;41(ehaa946):683.
- Halcox JP, Wareham K, Cardew A. Assessment of remote heart rhythm sampling using the AliveCor heart monitor to screen for atrial fibrillation: the REHEARSE-AF study.. Circulation 2017;136:1784-1794.
- Kraus MS, Rishniw M, Divers TJ. Utility and accuracy of a smartphone-based electrocardiogram device as compared to a standard base-apex electrocardiogram in the horse.. Res Vet Sci 2019;125:141-147.
- Vezzosi T, Sgorbini M, Bonelli F. Evaluation of a smartphone electrocardiograph in healthy horses: comparison with standard base-apex electrocardiography.. J Equine Vet Sci 2018;67:61-65.
- Corradini I, Fernández-Ruiz A, Barba M. Stall-side screening potential of a smartphone electrocardiogram recorded over both sides of the thorax in horses.. J Vet Intern Med 2020;34:2101-2108.
- Welch-Huston B, Durward-Akhurst S, Norton E. Comparison between smartphone electrocardiography and standard three-lead base apex electrocardiography in healthy horses.. Vet Record 2020;187:e70-e70.
- Alberti E, Stucchi L, Pesce V. Evaluation of a smartphone-based electrocardiogram device accuracy in field and in hospital conditions in horses.. Vet Record Open 2020;7:e000441.
- van Loon G, Paulussen E, Vera L, Van Steenkiste G, Decloedt A. Comparison of electrocardiogram quality from smartphone-based and standard ECG devices in healthy horses and horses with atrial fibrillation. 12th congress of the European College of Equine Internal Medicine (ECEIM), 2019.
- Advanced determinations: the basics. https://www.kardia.com/blog/articles/advanced-determinations/.
- Raceday responsibilities. https://www.racingvictoria.com.au/the-horse/veterinary-care/raceday-responsibilities.
- Allen K, Young L, Franklin S. Evaluation of heart rate and rhythm during exercise.. Equine Vet Educ 2016;28:99-112.
- Quantify agreement with kappa results. https://www.graphpad.com/quickcalcs/kappa1.cfm.
- Van Stralen KJ, Stel VS, Reitsma JB. Diagnostic methods I: sensitivity, specificity, and other measures of accuracy.. Kidney Int 2009;75:1257-1263.
- Van Steenkiste G, van Loon G, Crevecoeur G. Transfer learning in ECG classification from human to horse using a novel parallel neural network architecture.. Sci Rep 2020;10:1-12.
- Hesselkilde EM, Isaksen JL, Petersen BV. A novel approach for obtaining 12-lead electrocardiograms in horses.. J Vet Intern Med 2021;35:521-531.
- Gallant LR, Jacob SI, Tadros EM. Rapid screening for cardiac arrhythmias in competition draft horses.. Comp Exerc Physiol 2019;15:291-298.
Use Nutrition Calculator
Check if your horse's diet meets their nutrition requirements with our easy-to-use tool Check your horse's diet with our easy-to-use tool
Talk to a Nutritionist
Discuss your horse's feeding plan with our experts over a free phone consultation Discuss your horse's diet over a phone consultation
Submit Diet Evaluation
Get a customized feeding plan for your horse formulated by our equine nutritionists Get a custom feeding plan formulated by our nutritionists