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Acta veterinaria Scandinavica2014; 56(1); 3; doi: 10.1186/1751-0147-56-3

Application of optical coherence tomography enhances reproducibility of arthroscopic evaluation of equine joints.

Abstract: Arthroscopy is widely used in various equine joints for diagnostic and surgical purposes. However, accuracy of defining the extent of cartilage lesions and reproducibility in grading of lesions are not optimal. Therefore, there is a need for new, more quantitative arthroscopic methods. Arthroscopic optical coherence tomography (OCT) imaging is a promising tool introduced for quantitative detection of cartilage degeneration and scoring of the severity of chondral lesions. The aim of this study was to evaluate the inter-investigator agreement and inter-method agreement in grading cartilage lesions by means of conventional arthroscopy and with OCT technique. For this aim, 41 cartilage lesions based on findings in conventional and OCT arthroscopy in 14 equine joints were imaged, blind coded and independently ICRS (International Cartilage Repair Society) scored by three surgeons and one PhD-student. Results: The intra- and inter-investigator percentages of agreement by means of OCT (68.9% and 43.9%, respectively) were higher than those based on conventional arthroscopic imaging (56.7% and 31.7%, respectively). The intra-investigator Kappa coefficients were 0.709 and 0.565 for OCT and arthroscopy, respectively. Inter-investigator Kappa coefficients were 0.538 and 0.408 for OCT and arthroscopy, respectively. Conclusions: OCT can enhance reproducibility of arthroscopic evaluation of equine joints.
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Publication Date: 2014-01-10 PubMed ID: 24410869PubMed Central: PMC3901375DOI: 10.1186/1751-0147-56-3Google Scholar: Lookup
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  • Journal Article
  • Research Support
  • Non-U.S. Gov't

Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

This study evaluates a technique called optical coherence tomography (OCT) in improving the accuracy of identifying and grading cartilage lesions during arthroscopy in horses. The researchers found that OCT produced more consistent results across different investigators, suggesting an increased precision in grading cartilage injuries and potentially improving equine joint treatments.

Research Objectives

  • The main objective of the study was to examine the potential of Arthroscopic Optical Coherence Tomography (OCT), a new imaging technique, in enhancing the accuracy and reproducibility of arthroscopic evaluation of equine joints.
  • In particular, the study aimed to evaluate the inter-investigator agreement, which refers to the consistency of results from different investigators, and the inter-method agreement, the consistency in findings from conventional arthroscopy and those from OCT.

Methodology

  • The researchers used 41 cartilage lesions from 14 equine joints for this study.
  • These lesions were imaged using conventional arthroscopy and OCT, blind-coded, and then ICRS (International Cartilage Repair Society) scored by three separate surgeons and a PhD student. The ICRS score describes the condition of the cartilage.
  • The investigators then compared the ICRS scores determined by different evaluators, as well as those judged via the two different methods.

Results

  • The percentages of agreement, both intra- and inter-investigator, were higher for OCT than the conventional arthroscopic process. Intra-investigator agreement refers to consistency in an individual’s evaluation across different methods, while inter-investigator agreement involves consistency across different individuals using the same method.
  • Agreement percentages involving OCT were 68.9% (intra) and 43.9% (inter). In contrast, those from conventional arthroscopy were 56.7% and 31.7% respectively.
  • The Kappa coefficients for OCT were also higher than those for conventional arthroscopy, indicating more consistency in OCT results across different investigators.

Conclusions

  • The results of the study suggest that OCT enhances the reproducibility of arthroscopic evaluations in equine joints, therefore improving the quantitative measurement and detection of cartilage degeneration.
  • This could potentially improve the accuracy of diagnoses, subsequently enhancing the quality of treatments available for joint cartilage issues in horses.

Cite This Article

APA
Niemelä T, Virén T, Liukkonen J, Argüelles D, te Moller NC, Puhakka PH, Jurvelin JS, Tulamo RM, Töyräs J. (2014). Application of optical coherence tomography enhances reproducibility of arthroscopic evaluation of equine joints. Acta Vet Scand, 56(1), 3. https://doi.org/10.1186/1751-0147-56-3

Publication

Acta veterinaria Scandinavica
ISSN: 1751-0147
NlmUniqueID: 0370400
Country: England
Language: English
Volume: 56
Issue: 1
Pages: 3

Researcher Affiliations

Niemelä, Tytti
  • Department of Equine and Small Animal Medicine, University of Helsinki, Helsinki, Finland. tytti.niemela@helsinki.fi.
Virén, Tuomas
    Liukkonen, Jukka
      Argüelles, David
        te Moller, Nikae C R
          Puhakka, Pia H
            Jurvelin, Jukka S
              Tulamo, Riitta-Mari
                Töyräs, Juha

                  MeSH Terms

                  • Animals
                  • Arthroscopy / methods
                  • Arthroscopy / veterinary
                  • Cadaver
                  • Cartilage Diseases / pathology
                  • Cartilage Diseases / veterinary
                  • Cartilage, Articular / pathology
                  • Horse Diseases / pathology
                  • Horses
                  • Severity of Illness Index
                  • Tomography, Optical Coherence / methods
                  • Tomography, Optical Coherence / veterinary

                  References

                  This article includes 21 references
                  1. Neundorf RH, Lowerison MB, Cruz AM, Thomason JJ, McEven BJ, Hurtig MB. Determination of the prevalence and severity of metacarpophalangeal joint osteoarthritis in Thoroughbred racehorses via quantitative macroscopic evaluation. Am J Vet Res 2010;56:1284–1293.
                    doi: 10.2460/ajvr.71.11.1284pubmed: 21034319google scholar: lookup
                  2. Brittberg M, Winalski CS. Evaluation of cartilage injuries and repair. J Bon Joint Surg 2003;56(Suppl 2):58–69.
                    pubmed: 12721346
                  3. Verwilghen DR, Enzerink E, Martens A, Franck T, Balligand M, Henrotin Y, Detilleux J, Serteyn D. Relationship between arthroscopic joint evaluation and the levels of Coll2-1, Coll2-1NO2, and myeloperoxidase in the blood and synovial fluid of horses affected with osteochondrosis of the tarsocrural joint. Osteoarthr Cartil 2011;56:1323–1329.
                    doi: 10.1016/j.joca.2011.08.002pubmed: 21884810google scholar: lookup
                  4. Spahn G, Klinger HM, Baums M, Pinkepank U, Hofman GO. Reliability in arthroscopic grading of cartilage lesions. Results of a prospective blinded study for evaluation of inter-observer reliability. Arch Orthop Traum Su 2011;56:377–381.
                    doi: 10.1007/s00402-011-1259-8pubmed: 21249375google scholar: lookup
                  5. Spahn G, Klinger HM, Hofman GO. How valid is the arthroscopic diagnosis of cartilage lesions? Results of an opinion survey among highly experienced arthroscopic surgeons. Arch Orthop Traum Su 2009;56:1117–1121.
                    doi: 10.1007/s00402-009-0868-ypmc: PMC3085794pubmed: 19367409google scholar: lookup
                  6. Fercher AF. Optical coherence tomography – development, principles, applications. Z Med Phys 2010;56:251–276.
                    doi: 10.1016/j.zemedi.2009.11.002pubmed: 21134630google scholar: lookup
                  7. Huang YP, Saarakkala S, Töyräs J, Wang LK, Jurvelin JS, Zheng YP. Effects of optical beam angle on quantitative optical coherence tomography (OCT) in normal and surface degenerated bovine articular cartilage. Phys Med Biol 2011;56:1491–1509.
                    pubmed: 21191151
                  8. Chu CR, Williams A, Tolliver D, Kwoh CK, Bruno S, Irrgang JJ. Clinical optical coherence tomography of early articular cartilage degeneration in patients with degenerative meniscal tears. Arthritis Rheum 2010;56:1412–1420.
                    doi: 10.1002/art.27378pmc: PMC2972585pubmed: 20213801google scholar: lookup
                  9. Chu CR, Lin D, Geisler JL, Chu CT, Fu FH, Pan Y. Arthroscopic microscopy of articular cartilage using optical coherence topography. Am J Sports Med 2004;56:699–709.
                    doi: 10.1177/0363546503261736pubmed: 15090388google scholar: lookup
                  10. Li X, Martin S, Costas P, Ghanta R, Stamper DL, Harman M, Fujimoto JG, Brezinski ME. High-resolution optical coherence tomographic imaging of osteoarthritic cartilage during open knee surgery. Arthritis Res Ther 2005;56:R318–R323.
                    doi: 10.1186/ar1491pmc: PMC1065329pubmed: 15743479google scholar: lookup
                  11. Adams SB, Herz PR, Stamper DL, Roberts MJ, Bourquin S, Patel NA, Schneider K, Martin SD, Shortkroff S, Fujimoto JG, Brezinski ME. High-resolution imaging of progressive articular cartilage degeneration. J Orthop Res 2006;56:708–715.
                    doi: 10.1002/jor.20083pubmed: 16514626google scholar: lookup
                  12. te Moller NCR, Brommer H, Liukkonen J, Virén T, Timonen M, Puhakka P, Jurvelin JS, van Weeren R, Töyräs J. Arthroscope-guided optical coherence tomography provides detailed information on articular cartilage lesions in horse. Vet J 2013;56:589–595.
                    doi: 10.1016/j.tvjl.2013.05.031pubmed: 23810744google scholar: lookup
                  13. McIlwraith CW, Nixon AJ, Wright IA, Boening KJ. Diagnostic and surgical arthroscopy of the horse. Edinburgh: Mosby Elsevier; 2005.
                  14. Landis JR, Koch GG. The measurement of observer agreement for categorical data. Biometrics 1977;56:159–174.
                    doi: 10.2307/2529310pubmed: 843571google scholar: lookup
                  15. Kaleva E, Virén T, Saarakala S, Sahlman J, Sirola J, Puhakka J, Paatela T, Kröger H, Kiviranta I, Jurvelin JS, Töyräs J. Arthroscopic ultrasound assessment of articular cartilage in the human knee joint: a potential diagnostic method. Cartilage 2010;56:246–253.
                    pmc: PMC4300807pubmed: 26069583
                  16. Saarakkala S, Laasanen MS, Jurvelin JS, Törrönen K, Lammi MJ, Lappalainen R, Töyräs J. Ultrasound indententation of normal and spontaneously degenerated bovine articular cartilage. Osteoarth Cartil 2003;56:697–705.
                    doi: 10.1016/S1063-4584(03)00154-7pubmed: 12954241google scholar: lookup
                  17. Saarakkala S, Laasanen MS, Jurvelin JS, Töyräs J. Quantitative ultrasound imaging detects degenerative changes in articular surface and subchondral bone. Phys Med Biol 2006;56:5333–5346.
                    doi: 10.1088/0031-9155/51/20/017pubmed: 17019042google scholar: lookup
                  18. Virén T, Saarakkala S, Kaleva E, Nieminen HJ, Jurvelin JS, Töyräs J. Minimally invasive ultrasound method for intra-articular diagnostics of cartilage degeneration. Ultrasound Med Biol 2009;56:1546–1554.
                    doi: 10.1016/j.ultrasmedbio.2009.04.004pubmed: 19560251google scholar: lookup
                  19. Virén T, Saarakkala S, Jurvelin JS, Pulkkinen HJ, Tiitu V, Valonen P, Kiviranta I, Lammi MJ, Töyräs J. Quantitative evaluation of spontaneously and surgically repaired rabbit articular cartilage using intra-articular ultrasound method in situ. Ultrasound Med Biol 2010;56:833–839.
                    doi: 10.1016/j.ultrasmedbio.2010.02.015pubmed: 20420972google scholar: lookup
                  20. Virén T, Huang YP, Saarakkala S, Pulkkinen H, Tiitu V, Linjama A, Kiviranta I, Lammi MJ, Brunott A, Brommer H, Van Weeren R, Brama PA, Zheng YP, Jurvelin JS, Töyräs J. Comparison of ultrasound and optical coherence tomography techniques for evaluation of integrity of spontaneously repaired horse cartilage. J Med Eng Technol 2012;56:185–192.
                    doi: 10.3109/03091902.2012.663054pubmed: 22439802google scholar: lookup
                  21. Puhakka P, Ylärinne J, Lammi MJ, Saarakkala S, Kröger H, Virén T, Töyräs J. Light backscattering in optical coherence tomography depends on collagen and chondrocyte contents of agarose gel. San Antonio, Texas, USA: In Transactions of the Annual Meeting of Ortopaedic Reasearch Society; 2013.

                  Citations

                  This article has been cited 5 times.
                  1. Puhakka J, Paatela T, Salonius E, Muhonen V, Meller A, Vasara A, Kautiainen H, Kosola J, Kiviranta I. Enhancing the Reliability of Cartilage Repair Evaluation: A Simplified Volume-Based Approach. J Orthop Res 2025 Aug;43(8):1387-1395.
                    doi: 10.1002/jor.26096pubmed: 40350557google scholar: lookup
                  2. Puhakka J, Salonius E, Paatela T, Muhonen V, Meller A, Vasara A, Kautiainen H, Kosola J, Kiviranta I. Comparison Between Arthroscopic and Histological International Cartilage Repair Society Scoring Systems in Porcine Cartilage Repair Model. Cartilage 2022 Jan-Mar;13(1):19476035211069246.
                    doi: 10.1177/19476035211069246pubmed: 35098743google scholar: lookup
                  3. Wang Y, Liu S, Lou S, Zhang W, Cai H, Chen X. Application of optical coherence tomography in clinical diagnosis. J Xray Sci Technol 2019;27(6):995-1006.
                    doi: 10.3233/XST-190559pubmed: 31594279google scholar: lookup
                  4. Puhakka PH, Te Moller NC, Tanska P, Saarakkala S, Tiitu V, Korhonen RK, Brommer H, Virén T, Jurvelin JS, Töyräs J. Optical coherence tomography enables accurate measurement of equine cartilage thickness for determination of speed of sound. Acta Orthop 2016 Aug;87(4):418-24.
                    doi: 10.1080/17453674.2016.1180578pubmed: 27164159google scholar: lookup
                  5. Cernohorsky P, Kok AC, Bruin DM, Brandt MJ, Faber DJ, Tuijthof GJ, Kerkhoffs GM, Strackee SD, van Leeuwen TG. Comparison of optical coherence tomography and histopathology in quantitative assessment of goat talus articular cartilage. Acta Orthop 2015 Apr;86(2):257-63.
                    doi: 10.3109/17453674.2014.979312pubmed: 25350610google scholar: lookup
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