Arthroscopic removal of palmar/plantar osteochondral fragments (POF) in the metacarpo- and metatarso-phalangeal joints of standardbred trotters–outcome and possible genetic background to POF.
Abstract: A clinical material of 133 Standardbred horses with palmar/plantar osteochondral fragments (POF) in the metacarpo- and metatarsophalangeal joints were studied. All horses had their fragments removed with arthroscopic surgery. 102 of the horses were 3 years old or younger when surgery was performed. Anatomical localisations of the fragments were in agreement with earlier reports. There was no statistical significant difference in month of birth in the POF--group compared to the total population. Eighty % of the horses that had raced before surgery came back to racing. The racing performance relative to their contemporaries remained the same after the POF operation. 65% of the horses that had not raced before surgery raced after the operation. The breeding index BLUP (Best Linear Unbiased Prediction) was used to evaluate if the POF-horses differed genetically in racing ability from the total population. The average BLUP value of the POF group was 103.4 (+/- 0.65), while the mean BLUP value of the total population was 98.9. This difference was highly significant and indicated that these POF horses belonged to a selected group. A homogeneity test of allele frequencies in blood type systems was performed to evaluate if any genetic difference was persistent between POF horses compared to the total population. The statistical analysis of gene frequencies for alleles in blood type systems indicated a genetic discrimination in blood type systems D and Tf. 133 varmblodiga travhästar med lösa benfragment palmart/plantart i kotleden (POF, palmar/plantar osteochondral fragment) studerades. Hos samtliga hästar avlägsnades fragmenten med artroskopiteknik. 102 av hästarna var 3 år eller yngre då operationen utfördes. Den anatomiska lokalisationen överensstämde med tidigare rapporter. Det förelåg ingen signifikant skillnad i födelsemånad mellan POF-hästarna jämfört med hela populationen. 80% av de hästar som tävlat i lopp före operationen tävlade efter operationen och deras tävlingsresultat låg på samma nivå som före operationen. 65% av de hästar som inte tävlat före operationen kom till start efter operationen. Avelsindex BLUP (Best Linear Unbiased Prediction) användes för att utvärdera om POF-hästarna genetiskt skilde sig från totalpopulationens tävlingsresultat. Medelvärdet på BLUP för POF-hästarna var 103.4 (± 0.65) medan totalpopulationens BLUP-värde var 98.9. Denna skillnad var signifikant. Ett homogenitetstest av allelfrekvenserna i olika blodgrupps-och proteinsystem utfördes för att utröna om det förelåg genetiska skillnader mellan POF-hästarna och den totala populationen. Statistisk analys av genfrekvenserna visade genetisk heterogenitet för blodgruppssystem D och proteinsystem Tf.
Publication Date: 1998-05-21 PubMed ID: 9592942PubMed Central: PMC8050664DOI: 10.1186/BF03547803Google Scholar: Lookup
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- Journal Article
Summary
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The research investigates the removal of osteochondral fragments (POF) in the joints of Standardbred horses and the possible genetic basis for POF. The study found that horses which had fragments removed could still race successfully post-surgery, and there appeared to be some genetic differences in the POF group compared to the larger population.
Study Methodology and Findings
- The research examined 133 Standardbred horses that had osteochondral fragments (POF) in their metacarpo- and metatarsophalangeal joints. These fragments were then removed arthroscopically.
- The study found the anatomical locations of the fragments to be consistent with previous reports. It also found no significant difference in the month of birth for the horses studied.
Post-Surgery Results
- Eighty percent of the horses that had raced prior to surgery resumed racing post-operation. Their performance levels compared to their age-matched peers were unchanged by the surgery.
- 65% of those that had not raced prior to surgery began racing afterwards.
Genetic Findings
- The researchers used the breeding index BLUP (Best Linear Unbiased Prediction) to gauge if the POF horses differed genetically from the total population in terms of racing ability.
- The mean BLUP value of the POF group was found to be 103.4 (+/- 0.65), compared to 98.9 for the total population. This pointed to a significant difference, suggesting the POF horses were part of a genetically distinct group.
Blood Typing Analysis
- A homogeneity test was conducted to ascertain whether there was a persistent genetic difference between the POF horses and the total population.
- The statistical analysis indicated genetic discrimination in blood type systems D and Tf, showing potential genetic heterogeneity among the POF horses.
Cite This Article
APA
Roneus B, Arnason T, Collinder E, Rasmussen M.
(1998).
Arthroscopic removal of palmar/plantar osteochondral fragments (POF) in the metacarpo- and metatarso-phalangeal joints of standardbred trotters–outcome and possible genetic background to POF.
Acta Vet Scand, 39(1), 15-24.
https://doi.org/10.1186/BF03547803 Publication
Researcher Affiliations
- Department of Surgery and Medicine, Swedish University of Agricultural Sciences, Uppsala, Sweden.
MeSH Terms
- Age Factors
- Animals
- Arthrography / veterinary
- Arthroscopy / methods
- Arthroscopy / veterinary
- Female
- Forelimb
- Hindlimb
- Horse Diseases
- Horses / genetics
- Joints / surgery
- Male
- Orchiectomy
- Osteochondritis / epidemiology
- Osteochondritis / surgery
- Osteochondritis / veterinary
- Physical Conditioning, Animal
- Running
- Tarsal Joints / surgery
- Treatment Outcome
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Citations
This article has been cited 1 times.- Vos NJ. Incidence of osteochondrosis (dissecans) in Dutch warmblood horses presented for pre-purchase examination. Ir Vet J 2008 Jan 1;61(1):33-7.
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