Assessment of serum amyloid A concentrations and biochemical profiles in lactating jennies and newborn Ragusano donkey foals around parturition and one month after foaling in Sicily.
Abstract: A proper knowledge of biochemical parameters and inflammatory markers like serum amyloid A (SAA) is crucial in the monitoring of the first post-partum period in equids. Since no information is available on SAA for donkeys at this stage, 50 animals including jennies (n.10) and newborn foals (n.10) within 48 hr from foaling, and jennies (n.10) and foals (n.20) after 30 days from parturition were enrolled in the study to assess routine biochemical profile including SAA. Jennies showed higher alkaline phosphatase and lower bilirubins and cholesterol at 30 days of lactation compared to post-partum. Neonatal donkey foals showed significant higher concentrations of sodium, alkaline phosphatase, lactic dehydrogenase, blood urea nitrogen, creatinine and albumin within 48 hr of age, whilst higher values of phosphate and triglycerides were observed in older foals of 30 days of age. Significant higher SAA concentrations were recorded during the peripartum period in both jennies (25.95 ± 14.98 μg/ml) and newborn donkey foals (37.44 ± 19.75 μg/ml) compared to SAA values recorded in lactating jennies (2.38 ± 1.78 μg/ml) and in donkey foals (16.04 ± 18.14 μg/ml) at 30 days after parturition. The assessment of SAA in jennies and donkey foals around parturition and one month after foaling represents a valuable tool for the monitoring of health status during this stage when animals have to face with new challenges like the peak of lactation and extrauterine life adaptation respectively.
© 2021 The Authors. Reproduction in Domestic Animals published by Wiley-VCH GmbH.
Publication Date: 2021-11-29 PubMed ID: 34816505PubMed Central: PMC9300177DOI: 10.1111/rda.14048Google Scholar: Lookup
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Summary
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The research article is about a study conducted to understand the levels of serum amyloid A (SAA) and other biochemical parameters in lactating jennies and newborn donkey foals during and a month after birth. The results provide valuable insights for monitoring the health of these animals, particularly during the post-partum period.
Objective of the Study
- The aim of this research was to investigate biochemical values and the concentrations of an inflammatory marker known as serum amyloid A (SAA) in lactating jennies and newborn Ragusano donkey foals both around the time of birth and a month afterwards.
Methodology
- For this study, 50 donkeys were selected. This included ten lactating jennies and ten newborn foals less than 48 hours old, as well as ten jennies and twenty foals who were 30 days post-partum.
- The researchers conducted a biochemical examination that included measuring SAA levels.
Results
- The study found that lactating donkey mothers exhibited higher levels of an enzyme called alkaline phosphatase, along with lower bilirubin and cholesterol levels, 30 days post-partum compared to immediately after childbirth.
- Newborn donkeys exhibited higher sodium, alkaline phosphatase, lactic dehydrogenase, blood urea nitrogen, creatinine, and albumin levels during the first 48 hours of life. However, by the time they reached 30 days of age, they showed higher levels of phosphate and triglycerides.
- Both lactating jennies and newborn foals showed significantly higher SAA levels around the time of birth compared to 30 days post-partum.
Conclusion
- The study discovered that measuring SAA levels in lactating jennies and donkey foals during and after childbirth can provide useful information regarding their health status. This testing is particularly valuable during this stage of their lives as they adapt to lactation and life outside the uterus.
Cite This Article
APA
Bazzano M, Bonfili L, Eleuteri AM, Serri E, Scollo C, Yaosen Y, Tesei B, Laus F.
(2021).
Assessment of serum amyloid A concentrations and biochemical profiles in lactating jennies and newborn Ragusano donkey foals around parturition and one month after foaling in Sicily.
Reprod Domest Anim, 57(3), 262-268.
https://doi.org/10.1111/rda.14048 Publication
Researcher Affiliations
- School of Biosciences and Veterinary Medicine, University of Camerino, Matelica, Italy.
- School of Biosciences and Veterinary Medicine, University of Camerino, Matelica, Italy.
- School of Biosciences and Veterinary Medicine, University of Camerino, Matelica, Italy.
- School of Biosciences and Veterinary Medicine, University of Camerino, Matelica, Italy.
- Private Practitioner, Catania, Italy.
- School of Biosciences and Veterinary Medicine, University of Camerino, Matelica, Italy.
- School of Biosciences and Veterinary Medicine, University of Camerino, Matelica, Italy.
- School of Biosciences and Veterinary Medicine, University of Camerino, Matelica, Italy.
MeSH Terms
- Animals
- Animals, Newborn
- Equidae
- Female
- Horses
- Lactation
- Parturition
- Pregnancy
- Serum Amyloid A Protein
- Sicily
Conflict of Interest Statement
Authors declare no conflict of interest.
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Citations
This article has been cited 4 times.- Bazzano M, Arfuso F, Bonfili L, Eleuteri AM, McLean A, Serri E, Spaterna A, Laus F. Measuring Biochemical Variables and Serum Amyloid A (SAA) in Working Mules in Central Italy.. Animals (Basel) 2022 Oct 16;12(20).
- Hoeberg E, Sånge A, Saegerman C, Bohlin A, Nostell K, Durie I, Husted L, Öhman A, Jacobsen S, Berg L, Laursen SH, van Galen G. Serum amyloid A as a marker to detect sepsis and predict outcome in hospitalized neonatal foals.. J Vet Intern Med 2022 Nov;36(6):2245-2253.
- Bazzano M, Marchegiani A, Troisi A, McLean A, Laus F. Serum Amyloid A as a Promising Biomarker in Domestic Animals' Reproduction: Current Knowledge and Future Perspective.. Animals (Basel) 2022 Feb 25;12(5).
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