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Bilateral intraocular choristoma in a 2-day-old foal.

Abstract: A 2-d-old Warmblood colt was submitted for autopsy with a spectrum of bilateral ocular abnormalities. At postmortem examination, a constellation of lesions within the anterior segment included retention of ectodermal elements, compatible with choristoma. Ocular choristomas can be localized to different intraocular structures and are rare in equids. The morphologic features in our case were suggestive of abnormal corneal differentiation.
Publication Date: 2025-03-11 PubMed ID: 40070042PubMed Central: PMC11904920DOI: 10.1177/10406387251324997Google Scholar: Lookup
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  • Journal Article

Summary

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This paper discusses a case where a two-day-old colt was discovered to have a range of bilateral ocular abnormalities, including the rare occurrence of ocular choristomas located in different intraocular structures.

Clinical Presentation

  • The research revolves around a two-day-old Warmblood colt that was presented for autopsy.
  • The colt had a range of bilateral ocular abnormalities which appeared to be rare in equids, a family that includes horses and similar animals.

Postmortem Examination Findings

  • During the postmortem examination, the researchers discovered a collection of lesions within the anterior segment of the colt’s eye.
  • These lesions were comprised of ectodermal elements that were retained, a condition known as choristoma.

Ocular Choristomas

  • Ocular choristomas are rare in equids, making this case particularly noteworthy for the researchers.
  • These are benign tumors that occur when normal tissue grows in a place where it is not usually found. In this case, it was located in different intraocular structures within the colt’s eyes.

Abnormal Corneal Differentiation

  • The morphological features discovered in this case suggested an abnormal differentiation of the cornea, the transparent front part of the eye which covers the iris, pupil, and anterior chamber.
  • This abnormal differentiation could be connected to the observed ocular abnormalities and choristoma.

Cite This Article

APA
Morgan J, Curtis Shaw G, Weisman J, Cecere T, Carvallo-Chaigneau FR. (2025). Bilateral intraocular choristoma in a 2-day-old foal. J Vet Diagn Invest, 10406387251324997. https://doi.org/10.1177/10406387251324997

Publication

ISSN: 1943-4936
NlmUniqueID: 9011490
Country: United States
Language: English
Pages: 10406387251324997
PII: 10406387251324997

Researcher Affiliations

Morgan, Jasmine
  • Department of Biomedical Sciences and Pathobiology, Virginia-Maryland College of Veterinary Medicine, Virginia Tech, Blacksburg, VA, USA.
Curtis Shaw, Gillian
  • Comparative Ocular Pathology Laboratory of Wisconsin, University of Wisconsin, Madison, WI, USA.
Weisman, Jaime
  • Office of Laboratory Services, Virginia Department of Agriculture and Consumer Services, Richmond, VA, USA.
Cecere, Thomas
  • Department of Biomedical Sciences and Pathobiology, Virginia-Maryland College of Veterinary Medicine, Virginia Tech, Blacksburg, VA, USA.
Carvallo-Chaigneau, Francisco R
  • Department of Biomedical Sciences and Pathobiology, Virginia-Maryland College of Veterinary Medicine, Virginia Tech, Blacksburg, VA, USA.

Conflict of Interest Statement

The authors declare no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.

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Citations

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