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Veterinary ophthalmology2018; 22(1); 76-87; doi: 10.1111/vop.12571

Canine, feline, and equine corneal vascular neoplasia: A retrospective study (2007-2015).

Abstract: Corneal vascular neoplasms (hemangioma and hemangiosarcoma) are rare in all species. Reported cases are single case reports in a single species. Archived cases of corneal hemangioma and hemangiosarcoma from dogs, cats, and horses were obtained from the Comparative Ocular Pathology Lab of Wisconsin (COPLOW, Madison, WI), tabulated, and examined. This retrospective study describes the breeds, ages, tumor types, and characteristics of vascular neoplasms that appeared to be primarily corneal in location, in feline, canine, and equine patients, with gross and histologic images. There is a discussion of predisposing factors and speculated association with chronic ocular surface disease.
Publication Date: 2018-04-24 PubMed ID: 29689619DOI: 10.1111/vop.12571Google Scholar: Lookup
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Summary

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The study is about the analysis of rare corneal vascular neoplasms (hemangioma and hemangiosarcoma) in dogs, cats, and horses collected over the time from 2007 to 2015. They discuss the breed, age, and characteristics specific to the tumors, while also discussing potential links with ongoing eye surface diseases.

Objective of the Study

  • The research was aimed at listing and analyzing recorded cases of two specific types of corneal vascular neoplasms namely, hemangioma and hemangiosarcoma, in dogs, cats, and horses.
  • The researchers explored the characteristics, types, breeds and ages of the animals affected by these primarily corneal tumors.
  • They also speculate on the possible connection of these tumors with chronic diseases affecting the ocular surface.

Methods of the Study

  • The researchers obtained archived cases from Comparative Ocular Pathology Lab of Wisconsin (COPLOW) that spanned from 2007 to 2015 containing instances of corneal hemangioma and hemangiosarcoma in horses, cats, and dogs.
  • The data was then organised and reviewed, focusing on the primary area of the corneal.
  • Through thorough cover-to-cover case analysis, sizable information was gathered concerning the breeds, ages, tumor types as well as other attributes of the respective neoplasms.

Results and Discussion

  • Gross and histologic images were used to describe the tumours appearing in the canine, feline and equine patients.
  • Predisposing factors were also contemplated alongside investigating if these neoplasms have any association with chronic ocular surface diseases.
  • These types of tumors were confirmed as rare, but the information gathered provides significant insights into the occurrence of corneal vascular neoplasms across these three species.

Cite This Article

APA
Shank AMM, Teixeria LBC, Dubielzig RR. (2018). Canine, feline, and equine corneal vascular neoplasia: A retrospective study (2007-2015). Vet Ophthalmol, 22(1), 76-87. https://doi.org/10.1111/vop.12571

Publication

ISSN: 1463-5224
NlmUniqueID: 100887377
Country: England
Language: English
Volume: 22
Issue: 1
Pages: 76-87

Researcher Affiliations

Shank, Alba Maria M
  • Department of Anatomic Pathology, University of Wisconsin Madison, Madison, WI, USA.
Teixeria, Leandro B C
  • Department of Pathological Sciences, University of Wisconsin Madison, Madison, WI, USA.
Dubielzig, Richard R
  • Pathobiological Sciences, University of Wisconsin SVM, Madison, WI, USA.

MeSH Terms

  • Animals
  • Cat Diseases / epidemiology
  • Cats
  • Cornea
  • Dog Diseases / epidemiology
  • Dogs
  • Eye Diseases / epidemiology
  • Eye Diseases / veterinary
  • Hemangiosarcoma / epidemiology
  • Hemangiosarcoma / veterinary
  • Horse Diseases / epidemiology
  • Horses
  • Pedigree
  • Retrospective Studies
  • Vascular Neoplasms / epidemiology
  • Vascular Neoplasms / veterinary
  • Wisconsin / epidemiology

Citations

This article has been cited 5 times.
  1. Wotman KL, Chow L, Martabano B, Pezzanite LM, Dow S. Novel ocular immunotherapy induces tumor regression in an equine model of ocular surface squamous neoplasia. Cancer Immunol Immunother 2023 May;72(5):1185-1198.
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  4. Schafer KA, Atzpodien E, Bach U, Bartoe J, Booler H, Brassard J, Farman C, Kochi M, Lejeune T, Meseck E, Nolte T, Ramos M, Short B, Sorden S, Teixeira L, Turner O, Walling B, Yekkala K, Yoshizawa K. International Harmonization of Nomenclature and Diagnostic Criteria (INHAND): Nonproliferative and Proliferative Lesions of Nonrodent Ocular Tissues. Toxicol Pathol 2024 Oct;52(7):368-455.
    doi: 10.1177/01926233241283708pubmed: 39658869google scholar: lookup
  5. Telle MR, Betbeze C. Corneal Surgery in the Cat: Diseases, considerations and techniques. J Feline Med Surg 2022 May;24(5):429-441.
    doi: 10.1177/1098612X211061049pubmed: 34844459google scholar: lookup