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Home / Equine Research Bank / Can Vet J / Carbon dioxide laser as a surgical instrument for sarcoid th...
The Canadian veterinary journal = La revue veterinaire canadienne1998; 38(12); 773-776;

Carbon dioxide laser as a surgical instrument for sarcoid therapy–a retrospective study on 60 cases.

Abstract: The objective of this retrospective clinical study was to evaluate the carbon dioxide laser in the treatment of single and multiple sarcoids in 60 animals (44 horses, 13 donkeys, 2 mules, and 1 pony). Only animals that had been operated on 6 mo or more ago were included. Recurrence, new manifestation rate, and cosmetic outcome were determined. Recurrence was observed in 23 (38%) individuals. Animals with new sarcoid manifestation with or without recurrence of a sarcoid were observed in 35 cases (58%). Cases of scar tissue formation and, rarely, leukotrichia were observed. Animals presented with multiple sarcoids were more predisposed to recurrence. Donkeys showed a significantly lower recurrence rate than horses.
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Publication Date: 1998-01-14 PubMed ID: 9426943PubMed Central: PMC1576782
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  • Journal Article

Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

This research article explored the effectiveness of carbon dioxide laser treatment in managing sarcoids in animals—specifically horses, donkeys, mules, and ponies. Across 60 cases, they assessed recurrence rates, new sarcoid manifestation rates, and the cosmetic impact of the treatment.

Study Methodology

  • This study employed a retrospective design.
  • The researchers collected data from 60 previous cases where the carbon dioxide laser treatment was used on animals with single or multiple sarcoids.
  • The animals included in the study were as follows: 44 horses, 13 donkeys, 2 mules, and 1 pony.
  • Only animals that had undergone the laser treatment six months or longer before the study were included. This allowed the researchers to properly evaluate the efficacy and after-effects of the treatment.
  • The researchers considered factors such as recurrence, the appearance of new sarcoids, and cosmetic outcomes post-treatment.

Study Results

  • Results showed that 23 out of 60 animals experienced a recurrence of sarcoids after treatment, accounting for a 38% recurrence rate.
  • New manifestations of sarcoids, either with recurrence or without, were observed in 58% of the cases (35 out of 60 animals).
  • In some cases, the formation of scar tissue was reported, and occasionally leukotrichia—a condition characterised by white, colorless patches of hair—was noted.
  • The study found that animals presenting with multiple sarcoids were more likely to have recurrence post-treatment.

Species Variation

  • The research also highlighted a disparity between species in terms of the recurrence rate. For example, donkeys had a significantly lower rate of recurrence compared to horses.
  • This species variation provides valuable insight regarding the different responses to carbon dioxide laser treatment in different species and paves the way for future inquiries to determine the reasons behind this variation.

Implications of the Study

  • This study provides an evaluation of carbon dioxide laser treatment’s effectiveness on sarcoids in four different animal species. It provides a basis for understanding the recurrence rates and cosmetic impacts of the procedure and how these vary between animal species.
  • It suggests that while the treatment can be effective, the recurrence rate is notable, particularly in cases where the animal initially presented multiple sarcoids.
  • Whilst the reasons behind the recurrence and species variation aren’t explored in the study, their discovery presents an opportunity for further research to optimize treatment according to the animal species and sarcoid classification.

Cite This Article

APA
Carstanjen B, Jordan P, Lepage OM. (1998). Carbon dioxide laser as a surgical instrument for sarcoid therapy–a retrospective study on 60 cases. Can Vet J, 38(12), 773-776.

Publication

The Canadian veterinary journal = La revue veterinaire canadienne
ISSN: 0008-5286
NlmUniqueID: 0004653
Country: Canada
Language: English
Volume: 38
Issue: 12
Pages: 773-776

Researcher Affiliations

Carstanjen, B
  • Clinic for Farm Animals and Horses, School of Veterinary Medicine, University of Berne, Switzerland.
Jordan, P
    Lepage, O M

      MeSH Terms

      • Animals
      • Carbon Dioxide
      • Equidae
      • Female
      • Follow-Up Studies
      • Horse Diseases / classification
      • Horse Diseases / epidemiology
      • Horse Diseases / surgery
      • Horses
      • Incidence
      • Laser Therapy / methods
      • Laser Therapy / veterinary
      • Male
      • Neoplasm Recurrence, Local / veterinary
      • Retrospective Studies
      • Skin Neoplasms / classification
      • Skin Neoplasms / surgery
      • Skin Neoplasms / veterinary
      • Treatment Outcome

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      Citations

      This article has been cited 4 times.
      1. Saba C, Eggleston R, Parks A, Peroni J, Sjoberg E, Rice S, Tyma J, Williams J, Grosenbaugh D, Leard AT. ALVAC-fIL2, a feline interleukin-2 immunomodulator, as a treatment for sarcoids in horses: A pilot study. J Vet Intern Med 2022 May;36(3):1179-1184.
        doi: 10.1111/jvim.16425pubmed: 35416353google scholar: lookup
      2. Finlay M, Yuan Z, Morgan IM, Campo MS, Nasir L. Equine sarcoids: Bovine Papillomavirus type 1 transformed fibroblasts are sensitive to cisplatin and UVB induced apoptosis and show aberrant expression of p53. Vet Res 2012 Dec 4;43(1):81.
        doi: 10.1186/1297-9716-43-81pubmed: 23210796google scholar: lookup
      3. Beermann A, Clottu O, Reif M, Biegel U, Unger L, Koch C. A randomized placebo-controlled double-blinded study comparing oral and subcutaneous administration of mistletoe extract for the treatment of equine sarcoid disease. J Vet Intern Med 2024 May-Jun;38(3):1815-1824.
        doi: 10.1111/jvim.17052pubmed: 38529853google scholar: lookup
      4. Karalus W, Subharat S, Orbell G, Vaatstra B, Munday JS. Equine sarcoids: A clinicopathologic study of 49 cases, with mitotic count and clinical type predictive of recurrence. Vet Pathol 2024 May;61(3):357-365.
        doi: 10.1177/03009858231209408pubmed: 37937724google scholar: lookup
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