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Australian veterinary journal2012; 90(11); 451-456; doi: 10.1111/j.1751-0813.2012.00997.x

Case series of equine pituitary pars intermedia dysfunction in a tropical climate.

Abstract: The clinical manifestations of equine pituitary pars intermedia dysfunction (PPID) in temperate climates are well described. The classic presentation is that of an older animal with hirsutism, laminitis, poor muscle tone, pendulous abdomen and weight loss. This case series highlights the additional clinical signs of anhidrosis and heat stress with secondary exercise intolerance that were seen as primary presenting problems in equids with PPID in the hot, humid conditions of a tropical climate. The clinical signs resolved with medical treatment for PPID.
Publication Date: 2012-10-11 PubMed ID: 23106327DOI: 10.1111/j.1751-0813.2012.00997.xGoogle Scholar: Lookup
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  • Journal Article

Summary

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This article presents a series of cases where horses in a tropical climate developed symptoms of a condition called pituitary pars intermedia dysfunction (PPID), along with additional signs of anhidrosis (inability to sweat) and heat stress. All the symptoms improved after the horses received treatment for PPID.

Understanding the Research

  • The aim of this research study was to observe and document the different symptoms that horses in a tropical climate exhibited when they were suffering from a condition called pituitary pars intermedia dysfunction (PPID). The researchers were particularly interested in tracking signs of anhidrosis and heat stress, in addition to the standard symptoms of PPID.

What is PPID?

  • PPID, often found in older horses, is a condition that affects the pituitary gland, leading to symptoms such as excessive hair growth (hirsutism), lameness due to inflammation of the foot’s soft tissue (laminitis), poor muscle tone, a sagging belly (pendulous abdomen), and weight loss.

Research Findings

  • Over the course of the case series, the researchers found that equids (a term encompassing horses, donkeys, and mules) with PPID in hot, humid tropical climates were likely to exhibit additional symptoms of anhidrosis and heat stress.
  • Anhidrosis is a disorder where the animal becomes unable to sweat, causing difficulties in body temperature regulation, particularly in hot climates.
  • Heat stress is the physiological strain that an animal experiences when it is exposed to excessive heat and it can lead to a number of complications, including the inability to perform normal physical activities (exercise intolerance).

Treatment and Results

  • The symptoms observed in the equids improved with medication for PPID. This suggests that controlling the primary condition could help manage secondary symptoms such as anhidrosis and heat stress.

Conclusion

  • This research study provides valuable insight into the potential effects of PPID in equids living in tropical climates. It points to the importance of early identification and appropriate treatment of PPID in order to avoid further health complications related to heat stress.

Cite This Article

APA
Spelta CW, Axon JE. (2012). Case series of equine pituitary pars intermedia dysfunction in a tropical climate. Aust Vet J, 90(11), 451-456. https://doi.org/10.1111/j.1751-0813.2012.00997.x

Publication

ISSN: 1751-0813
NlmUniqueID: 0370616
Country: England
Language: English
Volume: 90
Issue: 11
Pages: 451-456

Researcher Affiliations

Spelta, C W
  • Townsville Vet Clinic, 32-34 Anne St, Aitkenvale, Queensland, 4814, Australia. caroline@townsvillevetclinic.com.au
Axon, J E

    MeSH Terms

    • Animals
    • Dopamine Agonists / therapeutic use
    • Female
    • Horse Diseases / diagnosis
    • Horse Diseases / drug therapy
    • Horse Diseases / epidemiology
    • Horses
    • Lameness, Animal / diagnosis
    • Male
    • Pergolide / therapeutic use
    • Pituitary Diseases / diagnosis
    • Pituitary Diseases / drug therapy
    • Pituitary Diseases / epidemiology
    • Pituitary Diseases / veterinary
    • Pituitary Gland, Intermediate / pathology
    • Prevalence
    • Prognosis
    • Treatment Outcome
    • Tropical Climate