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Science (New York, N.Y.)1965; 148(3668); 382-383; doi: 10.1126/science.148.3668.382

CHROMOSOME COMPLEMENT: DIFFERENCES BETWEEN EQUUS CABALLUS AND EQUUS PRZEWALSKII, POLIAKOFF.

Abstract: The chromosome number of the domestic horse is 2n = 64; different races have the same complement. The chromosomes of two Przewalski's horses (at Catskill Game Farm, New York), presumably ancestral wild horses from Mongolia, are identical: 2n = 66, with more acrocentric and fewer metacentric elements than the chromosomes of the domestic horse. This apparent difference in karyotype may help resolve the questions of "purity" in the relatively few remaining Przewalski's horses. Moreover, these findings are of interest in relation to the apparent fertility of hybrids between these species.
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Publication Date: 1965-04-16 PubMed ID: 14261533DOI: 10.1126/science.148.3668.382Google Scholar: Lookup
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  • Journal Article

Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

This study compared the chromosome number between domestic horses (Equus caballus) and Przewalski’s horses (Equus przewalskii) showing a difference in count. Understanding the distinct genetic makeup may help clarify questions regarding the purity and hybrid fertility of the endangered Przewalski’s horses.

Understanding the Context

  • The main focus of the research revolves around the comparison of chromosome numbers between two species of horses, namely the domestic horse (Equus caballus), and Przewalski’s horse (Equus przewalskii), which is considered an ancestral wild horse species from Mongolia.
  • The objective of the researchers was to analyze the differences in chromosomes between the two species. Such knowledge could help answer questions regarding the genetic reliability (‘purity’) of the remaining Przewalski’s horses and the feasibility of producing fertile offspring (‘hybrids’) between these two species.

Key Findings

  • The research found that the total chromosome number in a normal cell (2n) of the domestic horse is 64, with all races of domestic horses sharing the same complement.
  • On the contrary, they discovered that the chromosome number in Przewalski’s horses was 2n = 66. Moreover, such chromosomes revealed a higher count of acrocentric (centromere located close to one end of the chromosome) chromosomes and fewer metacentric (centromere located in the middle of the chromosome) chromosomes compared to the domestic horse.
  • The observation of an equal chromosomal number among the studied Przewalski’s horses indicates identical genetic traits, which suggests a high degree of genetic purity in these wild horses.
  • The noted differences between the chromosomal complements of these two horse species hold significant implications for the feasibility of hybrid fertility. This could mean genetic compatibility, heightened by the larger than normal count in the Przewalski horses.

Significance of the Study

  • This research represents an important contribution towards equine genetics, potentially helping to preserve the genetic purity of the critically endangered Przewalski’s horses.
  • Findings may provide clarity to questions about the genetic purity and hybrid fertility of the surviving Przewalski’s horses, leading towards actually implementing breeding and conservation programs.
  • The outcome could also inform the understanding of genetic diversity, evolution, and speciation processes within the Equus genus and serves as the basis for further genetic and chromosomal studies.

Cite This Article

APA
BENIRSCHKE K, MALOUF N, LOW RJ, HECK H. (1965). CHROMOSOME COMPLEMENT: DIFFERENCES BETWEEN EQUUS CABALLUS AND EQUUS PRZEWALSKII, POLIAKOFF. Science, 148(3668), 382-383. https://doi.org/10.1126/science.148.3668.382

Publication

Science (New York, N.Y.)
ISSN: 0036-8075
NlmUniqueID: 0404511
Country: United States
Language: English
Volume: 148
Issue: 3668
Pages: 382-383

Researcher Affiliations

BENIRSCHKE, K
    MALOUF, N
      LOW, R J
        HECK, H

          MeSH Terms

          • Animals
          • Chromosomes
          • Genetics
          • Horses
          • Karyometry
          • Karyotyping
          • Mongolia
          • New York
          • Ploidies
          • Research

          Citations

          This article has been cited 13 times.
          1. Flack N, Hughes L, Cassens J, Enriquez M, Gebeyehu S, Alshagawi M, Hatfield J, Kauffman A, Brown B, Klaeui C, Mabrouk IF, Walls C, Yeater T, Rivas A, Faulk C. The genome of Przewalski's horse (Equus ferus przewalskii). G3 (Bethesda) 2024 Aug 7;14(8).
            doi: 10.1093/g3journal/jkae113pubmed: 38805182google scholar: lookup
          2. Flack N, Hughes L, Cassens J, Enriquez M, Gebeyehu S, Alshagawi M, Hatfield J, Kauffman A, Brown B, Klaeui C, Mabrouk IF, Walls C, Yeater T, Rivas A, Faulk C. The genome of Przewalski's horse (Equus ferus przewalskii). bioRxiv 2024 Feb 28;.
            doi: 10.1101/2024.02.20.581252pubmed: 38464182google scholar: lookup
          3. Piras FM, Cappelletti E, Abdelgadir WA, Salamon G, Vignati S, Santagostino M, Sola L, Nergadze SG, Giulotto E. A Satellite-Free Centromere in Equus przewalskii Chromosome 10. Int J Mol Sci 2023 Feb 18;24(4).
            doi: 10.3390/ijms24044134pubmed: 36835543google scholar: lookup
          4. Turghan MA, Jiang Z, Niu Z. An Update on Status and Conservation of the Przewalski's Horse (Equus ferus przewalskii): Captive Breeding and Reintroduction Projects. Animals (Basel) 2022 Nov 15;12(22).
            doi: 10.3390/ani12223158pubmed: 36428386google scholar: lookup
          5. Klecel W, Martyniuk E. From the Eurasian Steppes to the Roman Circuses: A Review of Early Development of Horse Breeding and Management. Animals (Basel) 2021 Jun 22;11(7).
            doi: 10.3390/ani11071859pubmed: 34206575google scholar: lookup
          6. Metcalf JL, Song SJ, Morton JT, Weiss S, Seguin-Orlando A, Joly F, Feh C, Taberlet P, Coissac E, Amir A, Willerslev E, Knight R, McKenzie V, Orlando L. Evaluating the impact of domestication and captivity on the horse gut microbiome. Sci Rep 2017 Nov 14;7(1):15497.
            doi: 10.1038/s41598-017-15375-9pubmed: 29138485google scholar: lookup
          7. Der Sarkissian C, Ermini L, Schubert M, Yang MA, Librado P, Fumagalli M, Jónsson H, Bar-Gal GK, Albrechtsen A, Vieira FG, Petersen B, Ginolhac A, Seguin-Orlando A, Magnussen K, Fages A, Gamba C, Lorente-Galdos B, Polani S, Steiner C, Neuditschko M, Jagannathan V, Feh C, Greenblatt CL, Ludwig A, Abramson NI, Zimmermann W, Schafberg R, Tikhonov A, Sicheritz-Ponten T, Willerslev E, Marques-Bonet T, Ryder OA, McCue M, Rieder S, Leeb T, Slatkin M, Orlando L. Evolutionary Genomics and Conservation of the Endangered Przewalski's Horse. Curr Biol 2015 Oct 5;25(19):2577-83.
            doi: 10.1016/j.cub.2015.08.032pubmed: 26412128google scholar: lookup
          8. Huang J, Zhao Y, Shiraigol W, Li B, Bai D, Ye W, Daidiikhuu D, Yang L, Jin B, Zhao Q, Gao Y, Wu J, Bao W, Li A, Zhang Y, Han H, Bai H, Bao Y, Zhao L, Zhai Z, Zhao W, Sun Z, Zhang Y, Meng H, Dugarjaviin M. Analysis of horse genomes provides insight into the diversification and adaptive evolution of karyotype. Sci Rep 2014 May 14;4:4958.
            doi: 10.1038/srep04958pubmed: 24828444google scholar: lookup
          9. Achilli A, Olivieri A, Soares P, Lancioni H, Hooshiar Kashani B, Perego UA, Nergadze SG, Carossa V, Santagostino M, Capomaccio S, Felicetti M, Al-Achkar W, Penedo MC, Verini-Supplizi A, Houshmand M, Woodward SR, Semino O, Silvestrelli M, Giulotto E, Pereira L, Bandelt HJ, Torroni A. Mitochondrial genomes from modern horses reveal the major haplogroups that underwent domestication. Proc Natl Acad Sci U S A 2012 Feb 14;109(7):2449-54.
            doi: 10.1073/pnas.1111637109pubmed: 22308342google scholar: lookup
          10. Goto H, Ryder OA, Fisher AR, Schultz B, Kosakovsky Pond SL, Nekrutenko A, Makova KD. A massively parallel sequencing approach uncovers ancient origins and high genetic variability of endangered Przewalski's horses. Genome Biol Evol 2011;3:1096-106.
            doi: 10.1093/gbe/evr067pubmed: 21803766google scholar: lookup
          11. Trifonov VA, Stanyon R, Nesterenko AI, Fu B, Perelman PL, O'Brien PC, Stone G, Rubtsova NV, Houck ML, Robinson TJ, Ferguson-Smith MA, Dobigny G, Graphodatsky AS, Yang F. Multidirectional cross-species painting illuminates the history of karyotypic evolution in Perissodactyla. Chromosome Res 2008;16(1):89-107.
            doi: 10.1007/s10577-007-1201-7pubmed: 18293107google scholar: lookup
          12. Hedrick PW, Parker KM, Miller EL, Miller PS. Major histocompatibility complex variation in the endangered Przewalski's horse. Genetics 1999 Aug;152(4):1701-10.
            doi: 10.1093/genetics/152.4.1701pubmed: 10430594google scholar: lookup
          13. Ishida N, Oyunsuren T, Mashima S, Mukoyama H, Saitou N. Mitochondrial DNA sequences of various species of the genus Equus with special reference to the phylogenetic relationship between Przewalskii's wild horse and domestic horse. J Mol Evol 1995 Aug;41(2):180-8.
            doi: 10.1007/BF00170671pubmed: 7666447google scholar: lookup
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