Chronobiology and the horse: recent revelations and future directions.
Abstract: The circadian system provides animals with a means to adapt their internal physiology to the constantly changing environmental stimuli that exist on a rotating planet. Light information is translated into molecular timing mechanisms within pacemaker cells of the mammalian hypothalamic suprachiasmatic nucleus (SCN) via transcriptional-translational feedback loops. Humoral and neural outputs from this 'master' clock result in circadian rhythms of physiology and behaviour. The larger circadian system involves SCN synchronisation of cellular clocks throughout the organism such that individual organs can adapt their specific function to the time of day. In the short history of this scientific field, the vast majority of mammalian chronobiological research has been conducted using small laboratory animals. This review examines what these studies have revealed, discusses how recent chronobiological findings in the horse compare to what is known and highlights how the principles of circadian biology are applicable to equine husbandry and veterinary care.
Copyright (c) 2009 Elsevier Ltd. All rights reserved.
Publication Date: 2009-05-07 PubMed ID: 19427248DOI: 10.1016/j.tvjl.2009.04.013Google Scholar: Lookup
The Equine Research Bank provides access to a large database of publicly available scientific literature. Inclusion in the Research Bank does not imply endorsement of study methods or findings by Mad Barn.
- Journal Article
- Review
Summary
This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.
This research delves into the biological clocks, or circadian rhythms, present in horses and how these rhythms influence their physiology and behavior. The study further explores how this understanding can be leveraged for improved husbandry and veterinary care of horses.
Understanding the Circadian System
- The study delves into the importance of the circadian system, which facilitates an animal’s adaptation to changing environmental stimuli. An essential concept for living organisms, the circadian system helps maintain internal balance and respond to environmental changes.
- The process involves light information being transformed into molecular timing mechanisms within the specialized cells of a region in the brain called the suprachiasmatic nucleus (SCN). This serves as the ‘master’ clock governing behaviour and physiological rhythms in harmony with day-night cycles.
- Every organ in the animal body is understood to have an individual cellular clock. These cells function in synchronization with the overall circadian rhythm, allowing the body to adapt its functions concerning the time of day.
Chronobiological Research in Mammals and Horses
- Most of the research conducted in the field of chronobiology has so far been on small laboratory animals. This research has revealed significant insights into the workings of the circadian system.
- The review further delves into how these established principles can be applied to other organisms, particularly horses – a research area that hasn’t received as much attention.
- Studies in horses have unveiled similar molecular mechanisms and “master clocks,” although comparative study and analysis remain necessary to develop deeper insights. These comparisons can help decipher if there are any species-specific differences that need to be accounted for while applying chronobiology principles.
Application in Equine Husbandry and Veterinary Care
- Understanding the principles of chronobiology and the circadian systems of horses can lead to significant improvements in their husbandry and veterinary care practices.
- Consideration of the circadian rhythms can guide feeding schedules, activity hours, and even administering medical care at optimal times, leading to better health and wellbeing of the horses.
- Further research and advances in this field will allow us to manage horses and other animals more effectively and humanely, based on their internal biological clocks.
Cite This Article
APA
Murphy BA.
(2009).
Chronobiology and the horse: recent revelations and future directions.
Vet J, 185(2), 105-114.
https://doi.org/10.1016/j.tvjl.2009.04.013 Publication
Researcher Affiliations
- School of Agriculture, Food Science and Veterinary Medicine, University College Dublin, Belfield, Dublin 4, Ireland. Barbara.murphy@ucd.ie
MeSH Terms
- Animals
- Biological Clocks / physiology
- Brain / anatomy & histology
- Brain / physiology
- Circadian Rhythm / physiology
- Female
- Horses / physiology
- Male
- Models, Biological
- Periodicity
- Travel
Citations
This article has been cited 5 times.- Dauchy RT, Blask DE. Vivarium Lighting as an Important Extrinsic Factor Influencing Animal-based Research. J Am Assoc Lab Anim Sci 2023 Jan 1;62(1):3-25.
- Pohlin F, Brabender K, Fluch G, Stalder G, Petit T, Walzer C. Seasonal Variations in Heart Rate Variability as an Indicator of Stress in Free-Ranging Pregnant Przewalski's Horses (E. ferus przewalskii) within the Hortobágy National Park in Hungary. Front Physiol 2017;8:664.
- Watts LM, Browne JA, Murphy BA. Investigation of a non-invasive method of assessing the equine circadian clock using hair follicle cells. J Circadian Rhythms 2012 Oct 5;10(1):7.
- Murphy BA, Martin AM, Furney P, Elliott JA. Absence of a serum melatonin rhythm under acutely extended darkness in the horse. J Circadian Rhythms 2011 May 10;9:3.
- Rees H, Rzechorzek NM, Hughes RB, Dodd AN, Hodge JJL, Stevenson TJ, von Schantz M, Lucas RJ, Reece SE, Kyriacou CP, Millar AJ. BioClocks UK: driving robust cycles of discovery to impact. Philos Trans R Soc Lond B Biol Sci 2025 Jan 23;380(1918):20230345.
Use Nutrition Calculator
Check if your horse's diet meets their nutrition requirements with our easy-to-use tool Check your horse's diet with our easy-to-use tool
Talk to a Nutritionist
Discuss your horse's feeding plan with our experts over a free phone consultation Discuss your horse's diet over a phone consultation
Submit Diet Evaluation
Get a customized feeding plan for your horse formulated by our equine nutritionists Get a custom feeding plan formulated by our nutritionists