Clinical effects of betamethasone and hyaluronan, and of defocalized carbon dioxide laser treatment on traumatic arthritis in the fetlock joints of horses.
Abstract: The clinical effects of intra-articular betamethasone together with hyaluronan (betaM/HA) and treatment with a defocalized carbon dioxide laser on acute traumatic arthritis of the fetlock joint were assessed. The horses in these studies were selected using a thorough lameness examination, including intra-articular anaesthesia abolishing the lameness. This investigation comprised an observer-blind study, including 10 sport horses (10 joints), and a prospective study, including 180 sport horses (333 joints). In both studies, the material was divided into two groups treated with either betaM/HA or a carbon dioxide laser. The treatment doses were 12 mg of betaM, 20 mg of HA or 60 J/cm2 of treated area. Convalescence before training was 21 days for both groups in the observer-blind study. In the prospective study, convalescence in the betaM/HA group was 21 days but was only 7 days for the laser-treated group. In the observer-blind study, three of five treated joints recovered in both cohorts. In the prospective study, the groups had significantly different recovery rates--68% of the betaM/HA-treated joints and 80% of the carbon dioxide laser-treated joints. These results indicate that the defocalized carbon dioxide laser should be an applicable mode of treatment of acute traumatic synovitis in horses. However, the biochemical functions related to carbon dioxide laser treatment require further elucidation.
Publication Date: 2002-06-19 PubMed ID: 12069260DOI: 10.1046/j.1439-0442.2002.00445.xGoogle Scholar: Lookup
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- Journal Article
Summary
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The research article investigates the efficacy of two different treatments, intra-articular betamethasone combined with hyaluronan and a defocalized carbon dioxide laser, on traumatic arthritis in horses’ fetlock joints. The findings suggest that the laser treatment may be more effective, although more research is needed to understand its biochemical impacts.
Objective and Methodology
- The article’s primary objective is to assess the clinical effects of betamethasone combined with hyaluronan (betaM/HA) and defocalized carbon dioxide laser treatment on acute traumatic arthritis in horses’ fetlock joints.
- Two separate studies were undertaken to evaluate the effects, one being observer-blind and involving 10 sport horses (10 joints), and the other was prospective and involved 180 sport horses (333 joints).
- For the selection of the horses, a comprehensive lameness examination was undertaken, including intra-articular anaesthesia tests.
- The horses in both studies were segregated into two groups, where one group received betaM/HA treatment and the other received a carbon dioxide laser treatment.
- The treatment doses for the first group were 12 mg of betaM and 20 mg of HA. In contrast, the second group underwent carbon dioxide laser therapy with 60 J/cm2 of the treated area.
Treatment and Results
- In the observer-blind study, the convalescent period before training was 21 days for both groups. In the prospective study, it was 21 days for the betaM/HA group and 7 days for the laser-treated group.
- The observer-blind study revealed that both treatments appeared to be equally effective, with recovery in three out of five treated joints in both groups.
- However, the prospective study showcased significantly different recovery rates with 68% in the betaM/HA-treated joints and 80% in the carbon dioxide laser-treated joints.
Conclusions and Future Directions
- The results seem to suggest that the defocused carbon dioxide laser could be a suitable option for treating acute traumatic synovitis in horses.
- Despite the promising results, the researchers advocate for further investigations to understand the biochemical functions related to carbon dioxide laser treatment better.
Cite This Article
APA
Lindholm AC, Swensson U, de Mitri N, Collinder E.
(2002).
Clinical effects of betamethasone and hyaluronan, and of defocalized carbon dioxide laser treatment on traumatic arthritis in the fetlock joints of horses.
J Vet Med A Physiol Pathol Clin Med, 49(4), 189-194.
https://doi.org/10.1046/j.1439-0442.2002.00445.x Publication
Researcher Affiliations
- Mälaren Equine Clinic, Sigtuna, Sweden.
MeSH Terms
- Adjuvants, Immunologic
- Animals
- Anti-Inflammatory Agents, Non-Steroidal / administration & dosage
- Arthritis / surgery
- Arthritis / therapy
- Arthritis / veterinary
- Betamethasone / administration & dosage
- Carbon Dioxide
- Female
- Horse Diseases / surgery
- Horse Diseases / therapy
- Horses / injuries
- Hyaluronic Acid / administration & dosage
- Injections, Intra-Articular / veterinary
- Lameness, Animal / etiology
- Lameness, Animal / therapy
- Laser Therapy / methods
- Laser Therapy / veterinary
- Male
- Prospective Studies
- Single-Blind Method
Citations
This article has been cited 2 times.- Millis DL, Bergh A. A Systematic Literature Review of Complementary and Alternative Veterinary Medicine: Laser Therapy. Animals (Basel) 2023 Feb 14;13(4).
- Bergh A, Nyman G, Lundeberg T, Drevemo S. Effect of defocused CO2 laser on equine tissue perfusion. Acta Vet Scand 2006;47(1):33-42.
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