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Equine veterinary journal1980; 12(3); 113-117; doi: 10.1111/j.2042-3306.1980.tb03397.x

Clinical report of a paralytic syndrome affecting stallions, mares and foals on a thoroughbred studfarm.

Abstract: An outbreak of ataxia and paralysis on a Thoroughbred studfarm is reported. The cause of the disease was attributed to equid herpesvirus (EHV1) infection which stemmed from a single 10-month abortion on the studfarm. Stallions, mares and foals were all affected but the most serious clinical signs occurred in the mares. there were 35 out of 39 mares, 2 out of 4 stallions and 5 out of 39 foals which exhibited signs of ataxia. Nine mares became recumbent and died or were euthanased. Treatment with betamethasone and antibiotics was given. The outbreak was contained to one area of the stud apart from secondary spread to 2 in-contact mares on different premises.
Publication Date: 1980-07-01 PubMed ID: 6250820DOI: 10.1111/j.2042-3306.1980.tb03397.xGoogle Scholar: Lookup
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  • Journal Article

Summary

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This research article discusses a paralytic syndrome outbreak on a Thoroughbred studfarm, caused by equid herpesvirus (EHV1), affecting stallions, mares, and foals.

Background of the Research

  • The study was sparked by an outbreak of ataxia and paralysis on a Thoroughbred studfarm, a rare occurrence which impacted the well-being of the horses, showing a significant event within the animal healthcare field.
  • The cause of the disease was found to be equid herpesvirus (EHV1), originating from a single 10-month abortion on the farm.

Effects of the Outbreak

  • The breeding horses of all types; stallions, mares and foals, were infected. But, the mares showed the most serious clinical symptoms, indicating a potential element of gender or age vulnerability.
  • The report provides specific statistics, reporting that out of 39 mares, 35 exhibited signs of ataxia. Meanwhile, only 2 out of 4 stallions and 5 out of 39 foals showed similar symptoms. Therefore, the disease seems to be more prevalent or severe in mares.
  • The disease led to severe consequences, with nine of the affected mares becoming so impaired that they either died naturally or had to be euthanased.

Treatment and Spread Control

  • The treatment plan for the infected horses involved administering betamethasone and antibiotics. Nevertheless, the efficacy of these treatments is not mentioned in detail within the abstract.
  • The research article states that the outbreak was primarily contained within one area of the studfarm. There was, however, secondary spread to two mares who had contact with the affected horses and were based on different premises, indicating that the virus was contagious but could be contained with proper care and quarantine protocols.

Cite This Article

APA
Greenwood RE, Simson AR. (1980). Clinical report of a paralytic syndrome affecting stallions, mares and foals on a thoroughbred studfarm. Equine Vet J, 12(3), 113-117. https://doi.org/10.1111/j.2042-3306.1980.tb03397.x

Publication

ISSN: 0425-1644
NlmUniqueID: 0173320
Country: United States
Language: English
Volume: 12
Issue: 3
Pages: 113-117

Researcher Affiliations

Greenwood, R E
    Simson, A R

      MeSH Terms

      • Animals
      • Ataxia / diagnosis
      • Ataxia / therapy
      • Ataxia / veterinary
      • Female
      • Herpesviridae Infections / diagnosis
      • Herpesviridae Infections / therapy
      • Herpesviridae Infections / veterinary
      • Herpesvirus 1, Equid
      • Horse Diseases / diagnosis
      • Horse Diseases / therapy
      • Horses
      • Male
      • Paralysis / diagnosis
      • Paralysis / therapy
      • Paralysis / veterinary

      Citations

      This article has been cited 5 times.
      1. Price D, Barnum S, Mize J, Pusterla N. Investigation of the Use of Non-Invasive Samples for the Molecular Detection of EHV-1 in Horses with and without Clinical Infection. Pathogens 2022 May 13;11(5).
        doi: 10.3390/pathogens11050574pubmed: 35631095google scholar: lookup
      2. Klouth E, Zablotski Y, Goehring LS. Apparent Breed Predilection for Equid Herpesvirus-1-Associated Myeloencephalopathy (EHM) in a Multiple-Breed Herd. Pathogens 2021 Apr 29;10(5).
        doi: 10.3390/pathogens10050537pubmed: 33947126google scholar: lookup
      3. Nugent J, Birch-Machin I, Smith KC, Mumford JA, Swann Z, Newton JR, Bowden RJ, Allen GP, Davis-Poynter N. Analysis of equid herpesvirus 1 strain variation reveals a point mutation of the DNA polymerase strongly associated with neuropathogenic versus nonneuropathogenic disease outbreaks. J Virol 2006 Apr;80(8):4047-60.
      4. Allen G, Yeargan M, Costa LR, Cross R. Major histocompatibility complex class I-restricted cytotoxic T-lymphocyte responses in horses infected with equine herpesvirus 1. J Virol 1995 Jan;69(1):606-12.
        doi: 10.1128/JVI.69.1.606-612.1995pubmed: 7983765google scholar: lookup
      5. Chowdhury SI, Kubin G, Ludwig H. Equine herpesvirus type 1 (EHV-1) induced abortions and paralysis in a Lipizzaner stud: a contribution to the classification of equine herpesviruses. Arch Virol 1986;90(3-4):273-88.
        doi: 10.1007/BF01317376pubmed: 3015084google scholar: lookup