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The Cornell veterinarian1978; 68 Suppl 7; 133-150;

Clinicopathological manifestations of selected neoplasms.

Abstract: This report provides a general overview of the pathobiology of neoplasia, and an update on the clinicopathological manifestations of lymphosarcoma, mastocytoma, histiocytoma, melanoma, sarcoid and circumanal gland tumors in domestic animals. Neoplasia represents a continuum of events from reversible hyperplasia to irreversible and pathological changes in tissue growth patterns. In some instances the causes of this disease process have been identified, but the etiology of the majority of naturally occurring neoplasms remain unknown. Surgical excision is the preferred treatment for tumors, but is often more beneficial when combined with chemotherapy, radiotherapy or immunotherapy. The successful diagnosis and management of neoplastic disease in domestic animals necessitates a thorough awareness of the clinical presentation and biologic behavior of specific tumors on the part of veterinarians who provide health care for these species.
Publication Date: 1978-01-01 PubMed ID: 204450
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Summary

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This research article offers an overview of tumor pathobiology and updates on the clinical and pathological features of certain types of tumors in domestic animals, stressing the significance of understanding these features for successful diagnosis and management.

Introduction to Neoplasia

  • The paper begins by providing a general background on neoplasia, which refers to abnormal growth or production of cells, often leading to the formation of tumors. Such growth patterns can range from reversible hyperplasia, where cells proliferate excessively but can return to normal, to irreversible pathological alterations in growth patterns.

Specific Neoplasms in Domestic Animals

  • The paper further discusses selected types of neoplasms seen in domestic animals: lymphosarcoma, mastocytoma, histiocytoma, melanoma, sarcoid, and circumanal gland tumors. Each of these neoplasms has distinct clinicopathological features that are discussed in more detail.
  • While the causes of these tumors have been identified in some cases, the paper notes that the majority of naturally occurring neoplasms still have an unknown etiology, reinforcing the need for continued research into this area.

Treatment Options for Neoplasms

  • The article discusses several treatment options for these tumors, with surgical excision being presented as the most preferred method. However, chemotherapy, radiotherapy, or immunotherapy may also be used, especially in conjunction with surgery, demonstrating more beneficial results.

Importance of Tumor Awareness for Veterinarians

  • Finally, the research underlines the importance for veterinarians to have a comprehensive awareness and understanding of these specific tumors. Recognizing the clinical presentation and biological behavior of these tumors can enhance the accuracy of diagnosis and improve the effective management of neoplastic diseases in domestic animals.

Cite This Article

APA
Cockerell GL, MacCoy DM. (1978). Clinicopathological manifestations of selected neoplasms. Cornell Vet, 68 Suppl 7, 133-150.

Publication

ISSN: 0010-8901
NlmUniqueID: 0074245
Country: United States
Language: English
Volume: 68 Suppl 7
Pages: 133-150

Researcher Affiliations

Cockerell, G L
    MacCoy, D M

      MeSH Terms

      • Anal Gland Neoplasms / veterinary
      • Animals
      • Animals, Domestic
      • Cat Diseases
      • Cats
      • Cattle
      • Cattle Diseases
      • Dog Diseases
      • Dogs
      • Histiocytoma, Benign Fibrous / veterinary
      • Horse Diseases
      • Horses
      • Lymphoma, Non-Hodgkin / veterinary
      • Mast-Cell Sarcoma / veterinary
      • Melanoma / veterinary
      • Neoplasms / pathology
      • Neoplasms / surgery
      • Neoplasms / veterinary
      • Skin Neoplasms / veterinary

      References

      This article includes 28 references