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Veterinary dermatology2001; 12(4); 215-217; doi: 10.1046/j.0959-4493.2001.00257.x

Congenital hypotrichosis in a Percheron draught horse.

Abstract: A blue roan Percheron foal was born with poorly circumscribed patchy alopecia of the trunk and legs. Teeth and hoof development were normal. Alopecia was progressive, becoming almost complete by 1 year of age. Histopathological findings in a skin biopsy obtained at 7 months of age were consistent with severe follicular hypoplasia. Sebaceous glands, epitrichial sweat glands and arrector pilae muscles were normal. The horse is alive and otherwise well at 6 years of age, although adult stature is considered small for this breed. The clinical history and histopathological findings are most consistent with a form of congenital hypotrichosis.
Publication Date: 2001-08-09 PubMed ID: 11493406DOI: 10.1046/j.0959-4493.2001.00257.xGoogle Scholar: Lookup
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Summary

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The study discusses a case of a Percheron horse affected by congenital hypotrichosis, characterized by patchy fur loss since birth that became almost complete by the age of one. Despite the condition, the horse’s overall health and growth remained normal with minor variations.

Horse Characteristics and Observations

  • A blue roan Percheron foal, a breed of draught horse, was noticed to have patchy alopecia starting from its trunk and legs.
  • The condition worsened over time, with the horse losing almost all its hair by the time it turned one.
  • In all other aspects, such as the development of teeth and hooves, the horse was normal.
  • The horse’s size is somewhat smaller than average for its breed but is otherwise healthy and has lived to six years of age.

Scientific Examination and Findings

  • A skin biopsy was carried out when the horse was seven months old.
  • Upon examination of the biopsy sample, it was revealed that the horse suffered from severe follicular hypoplasia, a condition responsible for reducing the development of hair follicles.
  • The sebaceous glands, responsible for producing the oily substance sebum, were found to be functioning normally. Similarly, the sweat glands and arrector pilae muscles, responsible for causing hair follicles to stand erect during the phenomenon of ‘goosebumps’, were also normal.

Diagnosis

  • The symptoms and the results from the histopathological examination led to the diagnosis of congenital hypotrichosis, a genetic disorder that leads to hair loss or the inability to grow hair.
  • It’s a condition present at birth and is believed to be caused by a mutation in a gene responsible for hair growth.

Cite This Article

APA
Valentine BA, Hedstrom OR, Miller WH, Scott DW, Mathies S. (2001). Congenital hypotrichosis in a Percheron draught horse. Vet Dermatol, 12(4), 215-217. https://doi.org/10.1046/j.0959-4493.2001.00257.x

Publication

ISSN: 0959-4493
NlmUniqueID: 9426187
Country: England
Language: English
Volume: 12
Issue: 4
Pages: 215-217

Researcher Affiliations

Valentine, B A
  • Department of Biomedical Sciences, College of Veterinary Medicine, Oregon State University, Corvallis, Oregon 97331, USA. Beth.Valentine@orst.edu
Hedstrom, O R
    Miller, W H
      Scott, D W
        Mathies, S

          MeSH Terms

          • Animals
          • Diagnosis, Differential
          • Horse Diseases / congenital
          • Horse Diseases / diagnosis
          • Horse Diseases / pathology
          • Horses
          • Hypotrichosis / congenital
          • Hypotrichosis / diagnosis
          • Hypotrichosis / veterinary
          • Leg
          • Male

          Citations

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