Critical anthelmintic trials in ponies with oxfendazole and caviphos and concomitant studies on the spontaneous elimination of small strongylids.
Abstract: The efficacy of the benzimidazole, oxfendazole, and the organophosphate, caviphos, against gastrointestinal parasites of ponies was evaluated by the critcial test method. Oxfendazole (10 mg/kg of body weight) given in single oral doses was 100% effective against adult large strongylids (Strongylus vulgaris, Strongylus edentatus, and Strongylus equinus), 99% effective against adult small strongylids, and 97% effective against 4th-stage small strongylids (genera identified in order of frequency: Cylicostephanus, Cyathostomum, Cylicocyclus, Triodontophorus, Poteriostomum, Oesophagodontus, Cylicodontophorus, Gyalocephalus, and Craterostomum). Caviphos (40 mg/kg of body weight) admixed in the grain ration (horse crunch) was 89% effective against adult large strongylids (S vulgaris and S edentatus) and 99% effective against adult small strongylids (genera identified earlier in order of frequency above), but only 35% effective against 4th-stage small strongylids. Both drugs were effective (100%) against adult and immature pinworms (Oxyuris equi) but ineffective against Habronema spp and Draschia megastoma. Oxfendazole was only 11% effective against stomach bots (Gasterophilus spp); caviphos was 73% effective against these species. During a three-day pretreatment interval, about 34% of the total population of small strongylids was lost spontaneously from the 29 ponies.
Publication Date: 1979-03-01 PubMed ID: 475090
The Equine Research Bank provides access to a large database of publicly available scientific literature. Inclusion in the Research Bank does not imply endorsement of study methods or findings by Mad Barn.
- Journal Article
- Anthelmintic Treatment
- Benzimidazoles
- Clinical Study
- Cyathostomins
- Diagnosis
- Disease Diagnosis
- Disease Etiology
- Disease Treatment
- Drug
- Equine Health
- Gasterophilus Species
- Gastrointestinal Diseases
- Gastrointestinal Health
- Horses
- Parasites
- Pharmacodynamics
- Pharmacology
- Pony
- Strongyles
- Veterinary Medicine
- Veterinary Research
Summary
This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.
The research paper investigates the effectiveness of oxfendazole and caviphos, two types of anthelmintic drugs, in treating ponies with gastrointestinal parasites. Oxfendazole displayed high efficacy rates against multiple types of parasites while caviphos showed varied effectiveness.
Oxfendazole and Caviphos Efficacy
- Oxfendazole and Caviphos are two anthelmintic drugs used for treating parasitic infections in horses.
- The paper evaluates the effectiveness of these drugs on different gastrointestinal parasites, considering the drug dosage and the stage of life of the parasites.
- The results showed Oxfendazole was 100% effective against adult large strongylids, 99% effective against adult small strongylids, and 97% effective against the 4th-stage small strongylids.
- Caviphos demonstrated 89% efficacy against adult large strongylids, 99% efficacy against adult small strongylids. However, its effectiveness dropped to just 35% against 4th-stage small strongylids, reflecting its varied efficacy.
Performance Against Other Parasites
- Both drugs were fully effective (100%) against adult and immature pinworms (Oxyuris equi).
- However, they were found to be ineffective against Habronema spp and Draschia megastoma.
- Another noteworthy finding is regarding the stomach bots (Gasterophilus spp), against which Oxfendazole was only 11% effective, while Caviphos was 73% effective.
Natural Parasite Elimination
- The study also observed the natural loss of parasites in the ponies.
- About 34% of the total population of small strongylids spontaneously eliminated from the ponies’ system during a three-day pretreatment interval.
- This spontaneous elimination could have implications for how these horses are treated for such parasites in the future.
Cite This Article
APA
Colglazier ML.
(1979).
Critical anthelmintic trials in ponies with oxfendazole and caviphos and concomitant studies on the spontaneous elimination of small strongylids.
Am J Vet Res, 40(3), 384-386.
Publication
Researcher Affiliations
MeSH Terms
- Animals
- Anthelmintics / therapeutic use
- Benzimidazoles / therapeutic use
- Carbamates / therapeutic use
- Dichlorvos / analogs & derivatives
- Diptera
- Female
- Horses
- Insecticides / therapeutic use
- Male
- Organophosphorus Compounds
- Parasitic Diseases / drug therapy
- Parasitic Diseases, Animal
- Strongyle Infections, Equine / drug therapy
Citations
This article has been cited 1 times.- Jim GK, Booker CW, Guichon PT. Comparison of a combination of oxfendazole and fenthion versus ivermectin in feedlot calves. Can Vet J 1992 Sep;33(9):599-604.
Use Nutrition Calculator
Check if your horse's diet meets their nutrition requirements with our easy-to-use tool Check your horse's diet with our easy-to-use tool
Talk to a Nutritionist
Discuss your horse's feeding plan with our experts over a free phone consultation Discuss your horse's diet over a phone consultation
Submit Diet Evaluation
Get a customized feeding plan for your horse formulated by our equine nutritionists Get a custom feeding plan formulated by our nutritionists
