Cutaneous analgesia, hemodynamic and respiratory effects, and beta-endorphin concentration in spinal fluid and plasma of horses after acupuncture and electroacupuncture.
Abstract: To determine cutaneous analgesia, hemodynamic and respiratory effects, and beta-endorphin concentration in spinal fluid and plasma of horses after acupuncture and electroacupuncture (EA). Methods: 8 healthy 10- to 20-year-old mares that weighed between 470 and 600 kg. Methods: Each horse received 2 hours of acupuncture and 2 hours of PAES at acupoints Bladder 18, 23, 25, and 28 on both sides of the vertebral column as well as sham needle placement (control treatment). Each treatment was administered in a random order. At least 7 days elapsed between treatments. Nociceptive cutaneous pain threshold was measured by use of skin twitch reflex latency (STRL) and avoidance to radiant heat (< or = 50 degrees C) in the lumbar area. Skin temperature, cardiovascular and respiratory variables, and beta-endorphin concentration in spinal fluid (CSF-EN) and plasma (plasma-EN) were measured. Results: Acupuncture and PAES significantly increased STRL and skin temperature. The CSF-EN was significantly increased from baseline values 30 to 120 minutes after onset of PAES, but it did not change after acupuncture and control treatments. Heart and respiratory rates, rectal temperature, arterial blood pressure, Hct, total solids and bicarbonate concentrations, base excess, plasma-EN, and results of blood gas analyses were not significantly different from baseline values after acupuncture, PAES, and control treatments. Conclusions: Administration of PAES was more effective than acupuncture for activating the spinal cord to release beta-endorphins into the CSF of horses. Acupuncture and PAES provided cutaneous analgesia in horses without adverse cardiovascular and respiratory effects.
Publication Date: 2002-10-10 PubMed ID: 12371773DOI: 10.2460/ajvr.2002.63.1435Google Scholar: Lookup
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- Clinical Trial
- Journal Article
- Research Support
- Non-U.S. Gov't
Summary
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The research study aims to find out the effects of acupuncture and electroacupuncture on pain relief, cardiovascular and respiratory conditions, and beta-endorphin levels in horses. The findings show that both methods are effective for relieving skin pain without negative impacts on the heart and respiratory system. However, electroacupuncture is more effective in triggering the spinal cord release of beta-endorphins.
Study Participants and Methods
- The subjects of this experiment were eight healthy mares aged 10 to 20 years, each weighing between 470 and 600 kilograms.
- The horses were administered either acupuncture or electroacupuncture in rotating sequences over two-hour periods at specific acupoints (Bladder 18, 23, 25, and 28). These sessions were done seven days apart.
- The researchers also conducted a control treatment using sham needle placement.
- Measurements were taken on several indicators to judge the effects of the treatments – nociceptive cutaneous pain threshold, skin temperature, cardiovascular and respiratory variables, as well as beta-endorphin concentration in spinal fluid and plasma.
Findings of the Study
- Both acupuncture and electroacupuncture increased the skin’s pain threshold and its temperature, signifying the cutaneous analgesic effect of these treatments.
- Increases in beta-endorphin levels in the cerebrospinal fluid (indicative of pain relief) were observed within 30 to 120 minutes following electroacupuncture. These levels remained unchanged after acupuncture or control treatments.
- Both methods failed to make any significant differences in heart and respiratory rates, rectal temperature, arterial blood pressure, hematocrit, total solids and bicarbonate concentrations, base excess, and blood gas analyses.
Conclusions of the Study
- Electroacupuncture was found to be more effective than regular acupuncture in stimulating the release of beta-endorphins in the spinal cord, indicative of increased therapeutic potential.
- Both acupuncture and electroacupuncture offered skin analgesia without any detrimental effects on cardiovascular and respiratory variables in horses. This may imply potential for clinical use of these techniques for pain management in equine veterinary practice.
Cite This Article
APA
Skarda RT, Tejwani GA, Muir WW.
(2002).
Cutaneous analgesia, hemodynamic and respiratory effects, and beta-endorphin concentration in spinal fluid and plasma of horses after acupuncture and electroacupuncture.
Am J Vet Res, 63(10), 1435-1442.
https://doi.org/10.2460/ajvr.2002.63.1435 Publication
Researcher Affiliations
- Department of Veterinary Clinical Sciences, College of Veterinary Medicine, The Ohio State University, Columbus 43210, USA.
MeSH Terms
- Acupuncture Analgesia / veterinary
- Animals
- Blood Gas Analysis
- Blood Pressure
- Body Temperature
- Electroacupuncture / veterinary
- Female
- Heart Rate
- Hemodynamics / physiology
- Horses / blood
- Horses / cerebrospinal fluid
- Horses / physiology
- Respiratory Physiological Phenomena
- Time Factors
- beta-Endorphin / blood
- beta-Endorphin / cerebrospinal fluid
Citations
This article has been cited 4 times.- Iwe C, Schiele A, Passenegg V, Corona D, Bettschart-Wolfensberger R, Heitzmann V. Does perioperative electroacupuncture reduce postoperative pain in dogs undergoing ovariohysterectomy?. Front Vet Sci 2024;11:1513853.
- Shmalberg J, Memon MA. A Retrospective Analysis of 5,195 Patient Treatment Sessions in an Integrative Veterinary Medicine Service: Patient Characteristics, Presenting Complaints, and Therapeutic Interventions. Vet Med Int 2015;2015:983621.
- Bolt DM, Burba DJ, Hubert JD, Pettifer GR, Hosgood GL. Evaluation of cutaneous analgesia after non-focused extracorporeal shock wave application over the 3rd metacarpal bone in horses. Can J Vet Res 2004 Oct;68(4):288-92.
- Zijlstra FJ, van den Berg-de Lange I, Huygen FJ, Klein J. Anti-inflammatory actions of acupuncture. Mediators Inflamm 2003 Apr;12(2):59-69.
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