Diagnosis and surgical removal of a granulosa-theca cell tumor in a mare.

The research article discusses a case wherein an 8-year-old mare exhibiting stallion-like behavior was found to have a granulosa-theca cell tumor. The tumor was diagnosed through various methods and was successfully removed through surgery. Post-operative recovery was satisfactory and the mare was able to interact with other horses after 45 days.

Introduction and Diagnosis

• An 8-year-old mare began displaying abnormal, stallion-like behavior and also showed signs of aggression. This prompted an extensive examination in order to ascertain the root cause behind this behavioral change.
• A granulosa-theca cell tumor, which is a form of ovarian tumor, was initially diagnosed. This tentative diagnosis was made based on three factors: the mare’s history, a physical examination using transrectal palpation, and an ultrasound scan.
• Furthermore, serological tests showed high levels of testosterone and inhibin—hormones that are typically associated with the reproductive system and can be disrupted due to the presence of an ovarian tumor.

Surgical Intervention and Post-Operative Recovery

• The diagnosed tumor was surgically removed. This direct intervention was necessary to not only improve the bilogical health of the horse, but also to normalize its behavioral issues that were presumably linked to the tumor.
• Post-surgery, a histopathological examination of the tumor was conducted to conclusively verify the initial diagnosis. This examination confirmed that the tumor was, indeed, a granulosa-theca cell tumor.
• The mare recovered well from the surgery. Notably, by the 45th day following surgery, the mare could be turned out with other horses. This indicates that the behavioral issues had been resolved, in addition to the physical health of the mare.