Analyze Diet
Genome announcements2013; 1(5); e00683-13; doi: 10.1128/genomeA.00683-13

Draft Genome Sequence of Streptococcus equi subsp. zooepidemicus Strain S31A1, Isolated from Equine Infectious Endometritis.

Abstract: We present the draft genome sequence of Streptococcus equi subsp. zooepidemicus S31A1, a strain isolated from equine infectious endometritis in Denmark. Comparative analyses of this genome were done with four published reference genomes: S. zooepidemicus strains MGCS10565, ATCC 35246, and H70 and S. equi subsp. equi strain 4047.
Publication Date: 2013-09-05 PubMed ID: 24009118PubMed Central: PMC3764413DOI: 10.1128/genomeA.00683-13Google Scholar: Lookup
The Equine Research Bank provides access to a large database of publicly available scientific literature. Inclusion in the Research Bank does not imply endorsement of study methods or findings by Mad Barn.
  • Journal Article

Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

This article discusses the genetic analysis of a bacterial strain, Streptococcus equi subsp. zooepidemicus S31A1, found in horse infectious endometritis, with comparison made to four published genomes of similar strains.

Introduction and Aims of the Study

  • The objective of the research done in this study was to present and analyze the draft genome sequence of a specific bacterial strain — in specific, the Streptococcus equi subsp. zooepidemicus S31A1.
  • This strain had been isolated from equine infectious endometritis in Denmark, an infectious condition in the endometrial tissue of horses, typically caused by bacterial infection.

Methodology of the Study

  • The extracted genome sequence was meticulously compared with four previously detected and published genome sequences: those of S. zooepidemicus strains MGCS10565, ATCC 35246, and H70, as well as S. equi subsp. equi strain 4047.
  • The comparison was done to understand the genetic similarities and differences, which might suggest reasons for the varied strains’ behavior, bioactivity, and contagion potential.

Significance of the Study

  • The study can significantly contribute to the knowledge bank on the genomic structure of such bacterial strains, providing important insights that could lead to a deeper understanding of the factors causing infectious endometritis in horses.
  • Comparative genome analyses like this one are critical for identifying the variations between different strains of the same bacteria, which can help shed light on why some strains are more virulent or infectious than others.
  • Further, an understanding of the genomic sequence may offer potential targets for antibiotic development or aid in formulating better strategies for prevention and control of equine endometritis.

Cite This Article

APA
da Piedade I, Skive B, Christensen H, Bojesen AM. (2013). Draft Genome Sequence of Streptococcus equi subsp. zooepidemicus Strain S31A1, Isolated from Equine Infectious Endometritis. Genome Announc, 1(5), e00683-13. https://doi.org/10.1128/genomeA.00683-13

Publication

ISSN: 2169-8287
NlmUniqueID: 101595808
Country: United States
Language: English
Volume: 1
Issue: 5
PII: e00683-13

Researcher Affiliations

da Piedade, Isabelle
  • Department of Veterinary Disease Biology, Faculty of Health and Medical Sciences, University of Copenhagen, Frederiksberg C, Copenhagen, Denmark.
Skive, Bolette
    Christensen, Henrik
      Bojesen, Anders Miki

        References

        This article includes 14 references
        1. Timoney JF, Gillespie JH, Scott FW, Barlough JE. The genus Streptococcus. 1998 p 181–196 In Timoney JF. (ed), Hagan and Bruner's microbiology and infectious diseases of domestic animals, 8th ed. Comstock, Ithaca, NY.
        2. Roy K, Bisgaard M, Kyvsgaard NC, Christensen JP, Nielsen OL, Biswas PK, Pors SE, Bojesen AM. Pathogenicity of wild-type and small-colony variants of Streptococcus equi subsp. zooepidemicus in layer chickens.. Avian Pathol 2013 Aug;42(4):316-22.
          pubmed: 23721084doi: 10.1080/03079457.2013.798396google scholar: lookup
        3. Anzai T, Walker JA, Blair MB, Chambers TM, Timoney JF. Comparison of the phenotypes of Streptococcus zooepidemicus isolated from tonsils of healthy horses and specimens obtained from foals and donkeys with pneumonia.. Am J Vet Res 2000 Feb;61(2):162-6.
          pubmed: 10685688doi: 10.2460/ajvr.2000.61.162google scholar: lookup
        4. Priestnall S, Erles K. Streptococcus zooepidemicus: an emerging canine pathogen.. Vet J 2011 May;188(2):142-8.
          pmc: PMC7110628pubmed: 20570190doi: 10.1016/j.tvjl.2010.04.028google scholar: lookup
        5. Bisgaard M, Bojesen AM, Petersen MR, Christensen H. A major outbreak of Streptococcus equi subsp. zooepidemicus infections in free-range chickens is linked to horses.. Avian Dis 2012 Sep;56(3):561-6.
          pubmed: 23050474doi: 10.1637/10123-030712-reg.1google scholar: lookup
        6. Timoney JF. The pathogenic equine streptococci.. Vet Res 2004 Jul-Aug;35(4):397-409.
          pubmed: 15236673doi: 10.1051/vetres:2004025google scholar: lookup
        7. Poulin MF, Boivin G. A case of disseminated infection caused by Streptococcus equi subspecies zooepidemicus.. Can J Infect Dis Med Microbiol 2009 Summer;20(2):59-61.
          pmc: PMC2706407pubmed: 20514161doi: 10.1155/2009/538967google scholar: lookup
        8. Petersen MR, Nielsen JM, Lehn-Jensen H, Bojesen AM. Streptococcus equi subspecies zooepidemicus resides deep in the endometrium of the chronically infected mare. Clin. Theriogenol. 2009 1:161–167.
        9. Ricketts SW. Uterine and clitoral cultures. 2011 p 1963–1978 In McKinnon AO, Squires EL, Vaala WE, Varner DD. (ed), Equine reproduction, vol 2, 2nd ed. Wiley-Blackwell, Chichester, United Kingdom.
        10. Holden MT, Heather Z, Paillot R, Steward KF, Webb K, Ainslie F, Jourdan T, Bason NC, Holroyd NE, Mungall K, Quail MA, Sanders M, Simmonds M, Willey D, Brooks K, Aanensen DM, Spratt BG, Jolley KA, Maiden MC, Kehoe M, Chanter N, Bentley SD, Robinson C, Maskell DJ, Parkhill J, Waller AS. Genomic evidence for the evolution of Streptococcus equi: host restriction, increased virulence, and genetic exchange with human pathogens.. PLoS Pathog 2009 Mar;5(3):e1000346.
        11. Rasmussen CD, Haugaard MM, Petersen MR, Nielsen JM, Pedersen HG, Bojesen AM. Streptococcus equi subsp. zooepidemicus isolates from equine infectious endometritis belong to a distinct genetic group.. Vet Res 2013 Apr 18;44(1):26.
          doi: 10.1186/1297-9716-44-26pmc: PMC3640914pubmed: 23597033google scholar: lookup
        12. Beres SB, Sesso R, Pinto SW, Hoe NP, Porcella SF, Deleo FR, Musser JM. Genome sequence of a Lancefield group C Streptococcus zooepidemicus strain causing epidemic nephritis: new information about an old disease.. PLoS One 2008 Aug 21;3(8):e3026.
        13. Ma Z, Geng J, Zhang H, Yu H, Yi L, Lei M, Lu CP, Fan HJ, Hu S. Complete genome sequence of Streptococcus equi subsp. zooepidemicus strain ATCC 35246.. J Bacteriol 2011 Oct;193(19):5583-4.
          pmc: PMC3187426pubmed: 21914890doi: 10.1128/jb.05700-11google scholar: lookup
        14. Rissman AI, Mau B, Biehl BS, Darling AE, Glasner JD, Perna NT. Reordering contigs of draft genomes using the Mauve aligner.. Bioinformatics 2009 Aug 15;25(16):2071-3.

        Citations

        This article has been cited 2 times.
        1. Skive B, Rohde M, Molinari G, Braunstein TH, Bojesen AM. Streptococcus equi subsp. zooepidemicus Invades and Survives in Epithelial Cells.. Front Cell Infect Microbiol 2017;7:465.
          doi: 10.3389/fcimb.2017.00465pubmed: 29164073google scholar: lookup
        2. Ma W, Ma H, Fogerty FJ, Mosher DF. Bivalent ligation of the collagen-binding modules of fibronectin by SFS, a non-anchored bacterial protein of Streptococcus equi.. J Biol Chem 2015 Feb 20;290(8):4866-4876.
          doi: 10.1074/jbc.M114.612259pubmed: 25525266google scholar: lookup