Draft Genome Sequence of Taylorella equigenitalis Strain ERC_G2224 Isolated from the Semen of a Lipizzaner Stallion in South Africa.
Abstract: Taylorella equigenitalis is the causative agent of contagious equine metritis (CEM), a sexually transmitted infection of horses. We report here the genome sequence of T. equigenitalis strain ERC_G2224, isolated in 2015 from a semen sample collected in 1996 from a Lipizzaner stallion in South Africa.
Copyright © 2015 May et al.
Publication Date: 2015-10-15 PubMed ID: 26472845PubMed Central: PMC4611696DOI: 10.1128/genomeA.01205-15Google Scholar: Lookup
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Summary
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This research article presents the genomic sequence of Taylorella equigenitalis strain ERC_G2224, derived from a Lipizzaner stallion’s semen in South Africa, which causes a sexually transmitted infection in horses called contagious equine metritis (CEM).
Objective of the Research
- The main goal of this study was to decipher the genome sequence of Taylorella equigenitalis, a bacteria known to cause contagious equine metritis (CEM), a sexually transmitted infection among horses. This particular strain, named ERC_G2224, was isolated from the semen of a Lipizzaner stallion in South Africa in 2015. The semen sample was originally collected in 1996.
Significance of the Research
- The research is crucial as it provides valuable insights into the genetic makeup of the T. equigenitalis bacteria. Understanding the genome sequence can aid in developing effective treatment and prevention strategies against CEM.
- This study can be recognised as a significant step towards disease control in equine species. Working out the functions of different genes in this bacterium may enable scientists to pinpoint potential weak points that could be targeted with drugs or vaccines.
- Creation of a detailed genome map of T. equigenitalis also serves as a reference for future studies involving this bacterium and other related species.
Methodology of the Research
- Although the paper’s abstract does not provide specifics about the methods used to sequence the T. equigenitalis genome, it is typically done using various sequencing techniques such as Sanger sequencing, shotgun sequencing, or next-generation sequencing.
- After obtaining the genomic sequence, bioinformatics tools and analysis are used for genome assembly and annotation, which can help to identify and understand the function of individual genes within the genome.
Cite This Article
APA
May CE, Schulman ML, Howell PG, Lourens CW, Gouws J, Joone C, Monyai MS, le Grange M, Bezuidt OK, Harper CK, Guthrie AJ.
(2015).
Draft Genome Sequence of Taylorella equigenitalis Strain ERC_G2224 Isolated from the Semen of a Lipizzaner Stallion in South Africa.
Genome Announc, 3(5).
https://doi.org/10.1128/genomeA.01205-15 Publication
Researcher Affiliations
- Section of Reproduction, Department of Production Animal Studies, Faculty of Veterinary Science, University of Pretoria, Onderstepoort, South Africa.
- Section of Reproduction, Department of Production Animal Studies, Faculty of Veterinary Science, University of Pretoria, Onderstepoort, South Africa.
- Equine Research Centre, Faculty of Veterinary Science, University of Pretoria, Onderstepoort, South Africa.
- Equine Research Centre, Faculty of Veterinary Science, University of Pretoria, Onderstepoort, South Africa.
- Department of Veterinary Tropical Diseases, Faculty of Veterinary Science, University of Pretoria, Onderstepoort, South Africa.
- Equine Research Centre, Faculty of Veterinary Science, University of Pretoria, Onderstepoort, South Africa.
- Equine Research Centre, Faculty of Veterinary Science, University of Pretoria, Onderstepoort, South Africa.
- Equine Research Centre, Faculty of Veterinary Science, University of Pretoria, Onderstepoort, South Africa.
- Centre for Microbial and Environmental Genomics, Department of Genetics, Faculty of Natural Sciences, University of Pretoria, Hatfield, South Africa.
- Veterinary Genetics Laboratory, Faculty of Veterinary Science, University of Pretoria, Onderstepoort, South Africa.
- Equine Research Centre, Faculty of Veterinary Science, University of Pretoria, Onderstepoort, South Africa alan.guthrie@up.ac.za.
References
This article includes 8 references
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Citations
This article has been cited 1 times.- Hrala M, Andrla P, Bosák J, Fedrová P, Mugutdinov A, Karpíšková R, Nedbalcová K, Raichová J, Faldyna M, Hořín P, Šmajs D. Whole genome sequences of nine Taylorella equigenitalis strains isolated in the Czech Republic between 1982-2021: Molecular dating suggests a common ancestor at the time of Roman Empire. PLoS One 2025;20(1):e0315946.
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