Draft Genome Sequence of Taylorella equigenitalis Strain MCE529, Isolated from a Belgian Warmblood Horse.
Abstract: Taylorella equigenitalis is the causative agent of contagious equine metritis (CEM), a sexually transmitted infection of horses. We herein report the genome sequence of T. equigenitalis strain MCE529, isolated in 2009 from the urethral fossa of a 15-year-old Belgian Warmblood horse in France.
Copyright © 2014 Hébert et al.
Publication Date: 2014-11-26 PubMed ID: 25428969PubMed Central: PMC4246161DOI: 10.1128/genomeA.01214-14Google Scholar: Lookup
The Equine Research Bank provides access to a large database of publicly available scientific literature. Inclusion in the Research Bank does not imply endorsement of study methods or findings by Mad Barn.
- Journal Article
Summary
This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.
This research article focuses on the genome sequencing of Taylorella equigenitalis – the bacterium responsible for Contagious Equine Metritis (CEM), a horse sexually transmitted infection – specifically from the MCE529 strain isolated from a Belgian Warmblood horse.
About Taylorella equigenitalis and CEM
- This research focuses on the Taylorella equigenitalis bacterium, which causes Contagious Equine Metritis (CEM), a sexually transmitted infection (STI) in equines.
- CEM is primarily transmitted through breeding, either natural or artificial, and it can result in significant economic losses due to lowered fertility rates in mares and stallions.
- The disease is named after its main symptom – metritis, which is an inflammation of the uterus in horses.
Sequencing the Genome of T. equigenitalis
- This study reports on the genome sequence of the MCE529 strain of T. equigenitalis.
- This particular strain was isolated from the urethral fossa (a part of the reproductive tract) of a 15-year-old Belgian Warmblood horse in France in 2009.
- Genome sequencing is a method used to determine the complete DNA sequence of an organism’s genome at a single time. In this case, the sequence for the MCE529 strain of T. equigenitalis was determined.
Significance of the Research
- The genome sequence provides insight into the genetic makeup and properties of the MCE529 strain of T. equigenitalis, potentially shedding light on why this strain might cause CEM.
- This genomic information can be useful in developing diagnostic tools or therapies for the disease.
- Comparing the genome of this strain to others could also reveal key differences and similarities, which could further our understanding of the variations within this species and its potential impacts.
Cite This Article
APA
Hébert L, Touzain F, de Boisséson C, Breuil MF, Duquesne F, Laugier C, Blanchard Y, Petry S.
(2014).
Draft Genome Sequence of Taylorella equigenitalis Strain MCE529, Isolated from a Belgian Warmblood Horse.
Genome Announc, 2(6).
https://doi.org/10.1128/genomeA.01214-14 Publication
Researcher Affiliations
- ANSES, Dozulé Laboratory for Equine Diseases, Bacteriology and Parasitology Unit, Goustranville, France.
- ANSES, Ploufragan/Plouzané Laboratory, Viral Genetics and Bio-Security Unit, Université Européenne de Bretagne, Ploufragan, France.
- ANSES, Ploufragan/Plouzané Laboratory, Viral Genetics and Bio-Security Unit, Université Européenne de Bretagne, Ploufragan, France.
- ANSES, Dozulé Laboratory for Equine Diseases, Bacteriology and Parasitology Unit, Goustranville, France.
- ANSES, Dozulé Laboratory for Equine Diseases, Bacteriology and Parasitology Unit, Goustranville, France.
- ANSES, Dozulé Laboratory for Equine Diseases, Goustranville, France.
- ANSES, Ploufragan/Plouzané Laboratory, Viral Genetics and Bio-Security Unit, Université Européenne de Bretagne, Ploufragan, France.
- ANSES, Dozulé Laboratory for Equine Diseases, Bacteriology and Parasitology Unit, Goustranville, France sandrine.petry@anses.fr.
References
This article includes 10 references
- Sugimoto C, Isayama Y, Sakazaki R, Kuramochi S. Transfer of Haemophilus equigenitalis Taylor et al. 1978 to the genus Taylorella gen. nov. as Taylorella equigenitalis comb. nov.. Curr. Microbiol. 9:155–162.
- Nakashiro H, Naruse M, Sugimoto C, Isayama Y, Kuniyasu C. Isolation of Haemophilus equigenitalis from an aborted equine fetus.. Natl. Inst. Anim. Health Q. (Tokyo) 21:184–185.
- Matsuda M, Moore JE. Recent advances in molecular epidemiology and detection of Taylorella equigenitalis associated with contagious equine metritis (CEM).. Vet. Microbiol. 97:111–122.
- Schulman ML, May CE, Keys B, Guthrie AJ. Contagious equine metritis: artificial reproduction changes the epidemiologic paradigm.. Vet. Microbiol. 167:2–8.
- Duquesne F, Hébert L, Breuil MF, Matsuda M, Laugier C, Petry S. Development of a single multi-locus sequence typing scheme for Taylorella equigenitalis and Taylorella asinigenitalis.. Vet. Microbiol. 167:609–618.
- Hauser H, Richter DC, van Tonder A, Clark L, Preston A. Comparative genomic analyses of the Taylorellae.. Vet. Microbiol. 159:195–203.
- Hébert L, Moumen B, Duquesne F, Breuil M-F, Laugier C, Batto J-M, Renault P, Petry S. Genome sequence of Taylorella equigenitalis MCE9, the causative agent of contagious equine metritis.. J. Bacteriol. 193:1785.
- Chevreux B, Wetter T, Suhai S. Genome sequence assembly using trace signals and additional sequence information, p 45–56 In Giegerich R, et al. (ed), Proceedings of the German Conference on Bioinformatics.. GBF-Braunschweig and University of Bielefeld, Bielefeld, Germany .
- Chikhi R, Medvedev P. Informed and automated k-mer size selection for genome assembly.. Bioinformatics 30:31–37.
- Rissman AI, Mau B, Biehl BS, Darling AE, Glasner JD, Perna NT. Reordering contigs of draft genomes using the Mauve aligner.. Bioinformatics 25:2071–2073.
Citations
This article has been cited 2 times.- Hrala M, Andrla P, Bosák J, Fedrová P, Mugutdinov A, Karpíšková R, Nedbalcová K, Raichová J, Faldyna M, Hořín P, Šmajs D. Whole genome sequences of nine Taylorella equigenitalis strains isolated in the Czech Republic between 1982-2021: Molecular dating suggests a common ancestor at the time of Roman Empire. PLoS One 2025;20(1):e0315946.
- May CE, Schulman ML, Howell PG, Lourens CW, Gouws J, Joone C, Monyai MS, le Grange M, Bezuidt OK, Harper CK, Guthrie AJ. Draft Genome Sequence of Taylorella equigenitalis Strain ERC_G2224 Isolated from the Semen of a Lipizzaner Stallion in South Africa. Genome Announc 2015 Oct 15;3(5).
Use Nutrition Calculator
Check if your horse's diet meets their nutrition requirements with our easy-to-use tool Check your horse's diet with our easy-to-use tool
Talk to a Nutritionist
Discuss your horse's feeding plan with our experts over a free phone consultation Discuss your horse's diet over a phone consultation
Submit Diet Evaluation
Get a customized feeding plan for your horse formulated by our equine nutritionists Get a custom feeding plan formulated by our nutritionists
