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The Veterinary clinics of North America. Equine practice1987; 3(1); 59-80; doi: 10.1016/s0749-0739(17)30691-0

Drug therapy of respiratory disorders.

Abstract: The emphasis of this article is on the clinical application of drugs in therapy for treatment of disorders of the lower respiratory tract. Medications discussed include those used to enhance clearance of secretions and those employed to prevent and/or alleviate bronchoconstriction. Antimicrobial agents and respiratory stimulants are briefly mentioned.
Publication Date: 1987-04-01 PubMed ID: 3555731DOI: 10.1016/s0749-0739(17)30691-0Google Scholar: Lookup
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Summary

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This research article focuses on the use of various drugs in treating lower respiratory tract disorders, such as medications for secretion clearance, prevention of bronchoconstriction, antimicrobial agents, and respiratory stimulants.

Introduction

In this study, the researchers focus on exploring the clinical application of various drug therapies for the treatment of lower respiratory tract disorders. These disorders may include conditions like bronchitis, pneumonia, and Chronic Obstructive Pulmonary Disease (COPD), where the lower airways and lungs are affected, leading to symptoms such as shortness of breath, coughing, and difficulty breathing.

Medications for Secretion Clearance

  • The research discusses the use of medicines designed to enhance the clearance of secretions from the respiratory tract. These secretions, often in the form of excessive mucus or phlegm, can block the airways and contribute to an infection or increased difficulty in breathing.
  • Such medications work by thinning the mucus, making it easier to cough up, or by increasing the activity of the cilia (minute hair-like structures in the airways) that help move mucus out of the lungs.

Medications for Bronchoconstriction

  • Another significant focus of the research is the use of drugs employed to prevent and/or alleviate bronchoconstriction. Bronchoconstriction refers to the narrowing of the airways in the lungs due to the tightening of surrounding muscles.
  • Medicines such as bronchodilators help relax these muscles, allowing the airways to widen and making it easier for individuals to breathe. These medications are typically used in conditions such as asthma and COPD.

Antimicrobial Agents

  • The article briefly mentions the use of antimicrobial agents in treating lower respiratory tract disorders. These are drugs designed to kill or inhibit the growth of microorganisms and are often used to treat bacterial infections in the respiratory system, such as pneumonia.

Respiratory Stimulants

  • Lastly, the paper discusses respiratory stimulants. These medications serve to increase respiration rates and are often used for conditions where respiration may be suppressed or inadequate.
  • These could be used in treating chronic respiratory conditions, sleep-related breathing conditions, or in emergencies to stimulate breathing after a drug overdose or during anesthesia.

In conclusion, this paper provides a comprehensive analysis and discussion of the various types of drugs used in the treatment of lower respiratory tract disorders. It serves as a critical resource for healthcare practitioners in tailoring effective treatment strategies for patients suffering from such medical conditions.

Cite This Article

APA
Beech J. (1987). Drug therapy of respiratory disorders. Vet Clin North Am Equine Pract, 3(1), 59-80. https://doi.org/10.1016/s0749-0739(17)30691-0

Publication

ISSN: 0749-0739
NlmUniqueID: 8511904
Country: United States
Language: English
Volume: 3
Issue: 1
Pages: 59-80

Researcher Affiliations

Beech, J

    MeSH Terms

    • Adjuvants, Immunologic / therapeutic use
    • Animals
    • Anti-Bacterial Agents / therapeutic use
    • Bronchodilator Agents / therapeutic use
    • Expectorants / therapeutic use
    • Horse Diseases / drug therapy
    • Horses
    • Respiratory Tract Diseases / drug therapy
    • Respiratory Tract Infections / drug therapy
    • Respiratory Tract Infections / veterinary

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