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The Veterinary clinics of North America. Equine practice.

Periodical
Veterinary Medicine
Horse Diseases
Publisher:
W.B. Saunders,
Frequency: Three no. a year
Country: United States
Language: English
Start Year:1985 -
ISSN:
0749-0739 (Print)
1558-4224 (Electronic)
0749-0739 (Linking)
Impact Factor
1.1
2022
NLM ID:8511904
(DNLM):SR0053812(s)
(OCoLC):11078671
LCCN:sn 84006968
Classification:W1 VE929F
Diagnostic Ultrasound of the Equine Liver.
The Veterinary clinics of North America. Equine practice    July 9, 2026   Volume 42, Issue 2 231-248 doi: 10.1016/j.cveq.2026.04.013
Chope K.Ultrasound is readily available to most practitioners and can be used in a straightforward manner to assess the liver. The liver can be assessed for size, shape, echogenicity, and architecture. Findings such as masses, cysts, granulomas, and biliary distention can be relatively specific as to suspected disease process. Other findings may be nonspecific but are useful to confirm concerns and aid in refining differential diagnosis. Findings should be interpreted considering the clinicopathologic picture and sampling performed when appropriate. Ultrasound can and should be used to identify optima...
Clinical Signs of Liver Disease in Horses.
The Veterinary clinics of North America. Equine practice    June 11, 2026   S0749-0739(26)00016-7 doi: 10.1016/j.cveq.2026.04.001
Kopper JJ.Clinical signs associated with liver disease in horses are often a reflection of underlying hepatic dysfunction but typically vague rather than pathognomonic. Many observed clinical signs are subtle or not recognizable in the early stages of liver disease and thus may appear acute in onset despite an underlying chronic condition. Clinical signs reported in horses with liver disease include hyporexia or anorexia, weight loss, changes in demeanor, hepatic encephalopathy, colic signs, icterus, photosensitization, diarrhea, clinical coagulopathies, ascites, peripheral edema, steatorrhea, pruritus,...
Pharmaceutical and Nutraceutical Therapies for Liver Disease.
The Veterinary clinics of North America. Equine practice    June 11, 2026   S0749-0739(26)00036-2 doi: 10.1016/j.cveq.2026.04.014
Bozorgmanesh R, Magdesian KG.Liver dysfunction may reduce the metabolism of drugs that undergo extensive hepatic processing. This will lead to reduced clearance and elimination, and can cause accumulation of the drug, increasing the risk of toxicity. Pentoxifylline and ursodeoxycholic acid are 2 pharmaceuticals that can provide benefits for a variety of equine hepatic diseases. Nutraceuticals are frequently used in horses with hepatopathy, targeting oxidative stress, inflammation, and hepatocellular injury. Neutraceuticals such as S-adenosylmethionine, silymarin and vitamin E are most commonly used although extensive rese...
Syndrome of High Gamma-Glutamyl Transferase in Racehorses.
The Veterinary clinics of North America. Equine practice    June 5, 2026   S0749-0739(26)00024-6 doi: 10.1016/j.cveq.2026.04.009
Haughan J, Cathcart J, Tomlinson JE.Horses in racing and race training can develop high gamma-glutamyl transferase (GGT) syndrome (HGS), or increased GGT without overt evidence of primary liver disease. Current evidence points toward overtraining and a response to oxidative stress, but the etiology is incompletely understood. Evidence for an association of HGS with poor performance is mixed. Without a clear understanding of the etiology, the only evidence-based treatment option is rest or reduced training intensity. More research is needed to determine whether HGS is a physiologic adaptation, perhaps indicative of overtraining b...
Viral Hepatitis.
The Veterinary clinics of North America. Equine practice    June 3, 2026   S0749-0739(26)00021-0 doi: 10.1016/j.cveq.2026.04.006
Tomlinson J.Since 2012, 2 viral causes of hepatitis have been identified in horses. Much remains to be discovered about their transmission, risk factors for clinical disease, diagnosis, and treatment approaches. Equine parvovirus-hepatitis has been identified as the cause of acute hepatic necrosis, previously known as Theiler's disease. Equine hepacivirus is recognized as a cause of chronic fibrosing hepatitis. Diagnosis relies on ruling out other causes of hepatitis and documenting infection by serum or liver polymerase chain reaction. There is no direct antiviral for either condition and treatments are ...
Miscellaneous Equine Liver Conditions.
The Veterinary clinics of North America. Equine practice    May 28, 2026   S0749-0739(26)00025-8 doi: 10.1016/j.cveq.2026.04.010
Taylor SD, Brooks SN.Miscellaneous equine liver conditions not covered in other chapters include chronic active hepatitis, Tyzzer's disease, seasonal idiopathic hepatitis, neoplasia, and idiopathic persistent hyperbilirubinemia. Chronic active hepatitis refers to inflammatory and fibrotic liver disease with an unknown cause. Treatment is aimed at reducing inflammation. Tyzzer's disease is caused by Clostridium piliforme infection and causes acute necrotizing hepatitis in foals. Successful treatment with antimicrobial therapy and supportive care is rare. Seasonal idiopathic hepatitis is a winter disease of Midweste...
A Revised View on Equine Hypertriglyceridemia, Hyperlipidemia, and Hyperlipemia.
The Veterinary clinics of North America. Equine practice    May 28, 2026   S0749-0739(26)00022-2 doi: 10.1016/j.cveq.2026.04.007
Dunkel B.Hypertriglyceridemia, also known as hyperlipidemia or hyperlipemia, affects equids of all breeds and ages, mostly secondary to a negative energy balance triggered by a disease process. Increased triglyceride concentrations (TG) have been described in well-eating equids with endocrinopathies, atypical myopathy, severe liver disease, and after treatment with sodium-glucose transporter 2 inhibitors. The fact that equids can have substantially increased TG without showing clinical signs prompted reevaluation of the clinical effects of hypertriglyceridemia. As long as the consequences of high TG ar...
Biliary Disorders in Horses.
The Veterinary clinics of North America. Equine practice    May 28, 2026   S0749-0739(26)00020-9 doi: 10.1016/j.cveq.2026.04.005
Peek SF, Sebastian K.This review will mainly focus on the presentation, diagnosis, and treatment of cholangiohepatitis in adult horses. The condition is often accompanied by some degree of intrahepatic and/or extrahepatic biliary obstruction with "sludgy" bile or actual choleliths. In horses, these calculi are typically composed of calcium bilirubinate, rather than cholesterol. There is a propensity for cholangiohepatitis to become a recurrent, chronic condition and patient management should reflect this. Although much rarer, foreign body obstruction, neoplasia and, in some parts of the world, liver flukes can als...
Prognosis of Equine Liver Diseases.
The Veterinary clinics of North America. Equine practice    May 28, 2026   S0749-0739(26)00027-1 doi: 10.1016/j.cveq.2026.04.012
Durham AE.Prognostic information in equine liver disease can be gleaned from historical, clinical, clinicopathological, ultrasonographic, and histopathological features. However, given the multiple causes and subtypes of liver disease affecting horses worldwide, prognostic data might not be suitable for universal application across all cases. Most evidence has been established for horses with chronic hepatopathies and extrapolation to acute cases should be avoided. In chronic liver disease the presence and severity of clinical signs and serum markers including total globulins, albumin, and bile acids ar...
Equine Liver Histopathology.
The Veterinary clinics of North America. Equine practice    May 28, 2026   Volume 42, Issue 2 249-266 doi: 10.1016/j.cveq.2026.04.003
Jager MC.This review summarizes best practices for equine liver biopsy, including when to perform a biopsy, techniques for sample collection and handling, and strategies to optimize diagnostic yield. It discusses the interpretive framework used by pathologists, common diagnostic challenges, and prognostic scoring systems. Limitations such as sampling error and variability among observers are considered alongside ancillary testing, immunohistochemistry, and in situ hybridization. Emphasis is placed on the importance of communication between clinicians and pathologists to maximize diagnostic and prognost...
Evaluation and Management of the Horse with Head and Neck Disorders.
The Veterinary clinics of North America. Equine practice    April 9, 2026   S0749-0739(26)00013-1 doi: 10.1016/j.cveq.2026.02.001
Story MR, Nout-Lomas YS.Recognizing possible causes of equine head and neck problems requires a careful and systematic evaluation. While for some disorders reaching a diagnosis and treatment plan is relatively straightforward, for others this can be a complicated road requiring extensive diagnostic techniques, treatment trials, and management strategies. The ability to determine whether the patient is in a painful state, experiencing functional deficits, or in a combination of pain and dysfunction is critical to developing an effective treatment plan. Frequently, behavioral concerns often associated with pain must be...
Advanced Imaging of the Cranium and the Cervical Spine for Equine Neurologic Disease.
The Veterinary clinics of North America. Equine practice    April 2, 2026   Volume 42, Issue 1 31-46 doi: 10.1016/j.cveq.2025.12.011
Manso-Díaz G.Diagnostic imaging is essential for evaluating and managing neurologic disease in horses. Following clinical lesion, neurolocalization imaging modalities are often necessary to further characterize the disease process. However, which technology to use depends on various factors, including the patient's size, clinical signs, and the anatomic region. Current advances in imaging technology, in general, and the adaptation of different modalities for equine patients, in particular, have substantially improved our ability to evaluate the equine central nervous system. This article will summarize the...
Clinical Manifestations and Behaviors Associated with Equine Head and Neck Disorders.
The Veterinary clinics of North America. Equine practice    February 26, 2026   S0749-0739(26)00002-7 doi: 10.1016/j.cveq.2026.01.002
Nout-Lomas YS, Story MR.Equine head and neck disorders can present with a wide range of clinical manifestations, depending on the structures involved and disease process. Important components of the gastrointestinal, respiratory, ophthalmological, neurological, and musculoskeletal systems are contained within the head and neck, and clinical signs of disorders will result in expected clinical signs. However, clinical manifestations of disease are sometimes subtle, and when not recognized can lead to behavioral changes including undesired behaviors and poor sleep. Recognizing behavioral phenotypes of horses with proble...
Updates on Seizures and Epilepsy in the Horse.
The Veterinary clinics of North America. Equine practice    February 25, 2026   S0749-0739(25)00077-X doi: 10.1016/j.cveq.2025.12.009
Migliorisi A.The goal of this article is to provide the equine practitioners with a framework for a diagnostic algorithm for the patient presented with possible seizures/epilepsy. Using a comparative approach, a review of companion animal and human research is provided with the intention of expanding our current knowledge on seizure/epilepsy, as well as diagnostic and treatment strategies for equine patients.
Update on Idiopathic Trigeminal-Mediated Headshaking.
The Veterinary clinics of North America. Equine practice    February 20, 2026   S0749-0739(25)00071-9 doi: 10.1016/j.cveq.2025.12.003
Aleman M, Morales CJ.Idiopathic trigeminal-mediated headshaking is a painful neuropathic disorder characterized by sudden, violent, predominantly vertical head movements of unknown etiology. Clinical signs may be seasonal or persistent and triggered by light, sound, exercise, or tactile nasal stimulation. The pathophysiology is multifactorial, involving abnormal trigeminal nerve excitability influenced by hormonal, environmental, and dietary factors. Treatment is challenging and typically multimodal, aiming to reduce trigeminal hypersensitivity and improve quality of life.
Updates on Diagnosis and Treatment of Guttural Pouch Conditions.
The Veterinary clinics of North America. Equine practice    February 20, 2026   Volume 42, Issue 1 87-97 doi: 10.1016/j.cveq.2025.12.008
Mudge M, Hostnik LD.The complex anatomy and unique features of the equine guttural pouch create diagnostic and treatment challenges. Novel surgical approaches, as well as transendoscopic devices and medications, have improved the management of guttural pouch conditions, such as mycosis, empyema, tympany, and temporohyoid osteoarthropathy. Guidelines for Streptococcus equi subspecies equi diagnosis and disinfection protocols are strengthened by new evidence for point-of-care polymerase chain reaction, serial sampling for determining carrier status, and evaluation of disinfection techniques.
Disorders of the Equine Head and Neck: Paranasal Sinuses.
The Veterinary clinics of North America. Equine practice    February 18, 2026   Volume 42, Issue 1 79-85 doi: 10.1016/j.cveq.2025.12.012
Luedke LK.This article provides an overview of equine paranasal sinus disease with emphasis on relevant anatomy, diagnostic considerations, and commonly encountered pathologic conditions. It outlines the structure and drainage of the paranasal sinuses to establish a foundation for understanding disease development and spread. The discussion reviews available diagnostic modalities and their roles in localizing disease and determining underlying causes. Common sinus disorders are presented with attention to their general pathophysiology, diagnostic features, treatment approaches, and expected outcomes. Co...
Acquired and Degenerative Conditions of the Cervical Vertebral Column in Horses.
The Veterinary clinics of North America. Equine practice    February 12, 2026   S0749-0739(25)00078-1 doi: 10.1016/j.cveq.2025.12.010
Schmidt S, Swagemakers JH, le Jeune SS.The cervical vertebral column in horses plays a crucial role in movement, posture, and performance and disorders affecting it can cause pain, ataxia, or lameness. This review discusses major acquired (traumatic, infectious, neoplastic) and degenerative (osteoarthritis, foraminal stenosis, intervertebral disc disease) conditions. Acquired lesions often arise from trauma, bacterial infection, or neoplasia, with clinical signs ranging from neck pain to neurologic deficits. Degenerative disorders, particularly osteoarthritis of articular process joints, are common in the caudal cervical spine and ...
Congenital Cervical Vertebral and Spinal Cord Anomalies.
The Veterinary clinics of North America. Equine practice    February 6, 2026   S0749-0739(25)00073-2 doi: 10.1016/j.cveq.2025.12.005
Haussler KK.Congenital cervical vertebral anomalies in horses are structural changes in the neck vertebrae that develop during the fetal stage. These anomalies can vary in their severity and effects. Some horses may not show any clinical signs and can live normally, while others may develop serious problems such as spinal cord compression. This compression can lead to issues like ataxia or even paralysis, affecting the horse's mobility and quality of life. Recognizing and diagnosing these anomalies early are very important, as it helps guide decisions about the best treatment options and overall managemen...
Current and Future Central Nervous System Surgery-Part 1: Cervical Spinal Cord Compression.
The Veterinary clinics of North America. Equine practice    February 6, 2026   S0749-0739(25)00074-4 doi: 10.1016/j.cveq.2025.12.006
Nelson BB, Easley JT.Ventral cervical stabilization remains the primary surgical approach, in general, for horses with spinal cord compression. Advancements in volumetric imaging offer a more comprehensive understanding of central nervous system dysfunction elucidating that other modes of compression exist. Minimally invasive instrumentation and computer-assisted surgery are expanding therapeutic possibilities for cervical vertebral compressive myelopathy, radiculopathy, vertebral fractures, and intracranial or intraspinal masses. Emerging techniques-such as articular process joint fixation, targeted decompression...
Biomechanics of the Head and Neck.
The Veterinary clinics of North America. Equine practice    February 6, 2026   S0749-0739(25)00072-0 doi: 10.1016/j.cveq.2025.12.004
Clayton HM.The horse's head and neck account for about 10% of body weight, and this, combined with the fact that they are cantilevered in front of the trunk, produces considerable leverage around the joints at the base of the neck. During locomotion, the neck is moved primarily by gravitational and inertial forces controlled by eccentric-concentric cycles of contraction in the topline muscles assisted by energy-saving, stretch-recoil cycles in the nuchal ligament. The functional part of the nuchal ligament is the caudal funicular region and the lamellae to the second cervical vertebra that acts as the po...
Current and Future Central Nervous System Surgery-Part 2: Radiculopathy, Vertebral Fractures, and Intracranial Surgery.
The Veterinary clinics of North America. Equine practice    February 6, 2026   S0749-0739(25)00075-6 doi: 10.1016/j.cveq.2025.12.007
Nelson BB, Easley JT.Equine neurosurgery is a challenge for many surgeons, particularly when central nervous system (CNS) disease is not addressed through ventral cervical stabilization, the most performed neurosurgical procedure. Advances in diagnostic imaging, minimally invasive instrumentation, and computer-assisted surgery are expanding therapeutic possibilities beyond cervical vertebral compressive myelopathy, including radiculopathy, vertebral fractures, and intracranial or intraspinal masses. Emerging techniques-such as percutaneous foraminotomy, facet fixation, targeted decompression, novel implant systems...
Disorders of the Equine Head and Neck: Larynx and Pharynx.
The Veterinary clinics of North America. Equine practice    February 6, 2026   Volume 42, Issue 1 61-78 doi: 10.1016/j.cveq.2025.12.002
Luedke LK.This comprehensive review outlines the anatomy, diagnostic methods, pathophysiology, treatment, and prognosis of common equine upper airway disorders. It discusses the structure and function of the larynx and pharynx, and details diagnostic tools such as endoscopy and ultrasound. Major conditions-recurrent laryngeal neuropathy, arytenoid chondropathy, epiglottic entrapment, dorsal displacement of the soft palate, and nasopharyngeal collapse-are described with emphasis on their etiology, clinical signs, and management options for optimizing performance outcomes.
Ocular Causes for Undesired Behaviors in the Horse.
The Veterinary clinics of North America. Equine practice    January 28, 2026   S0749-0739(25)00069-0 doi: 10.1016/j.cveq.2025.12.001
Knickelbein KE.Numerous ocular diseases cause visual impairment and induce ocular pain that may be associated with undesired behaviors in horses. Horses with ocular pain, indicated by the presence of blepharospasm, blepharoedema, ocular discharge or rubbing the eye, should be rested from work to avoid worsening the ocular disease and to avoid undesired behaviors associated with pain or vision impairment. Horses with ocular disease are frequently head shy. Some stoic horses may not have obvious outward clinical signs despite significant visual impairment, and as such, undesired behaviors such as spooking, bal...
Complications Associated with Equine Diagnostic and Elective procedures.
The Veterinary clinics of North America. Equine practice    November 10, 2025   Volume 41, Issue 3 453-472 doi: 10.1016/j.cveq.2025.08.012
Morales CJ, Costa LRR.The practice of medicine has always been associated with complications. In fact, in its early stages, these complications contributed to the understanding of certain diseases and advancement of the medical field. In equine practice, virtually every procedure carries an associated risk. In fact, even procedures that would have minimal risk in human medicine may pose significant risk in equine practice owing to the unique nature of the horse. For instance, a simple rectal palpation could result in a rectal tear following an unexpected movement of the patient. Thus, extrapolations of complication...
Complications in Theriogenology.
The Veterinary clinics of North America. Equine practice    October 7, 2025   Volume 41, Issue 3 579-594 doi: 10.1016/j.cveq.2025.08.007
Gomes VCL, Strachota JR.This article explores key complications in equine reproduction, focusing on their causes, diagnosis, treatment, and prevention. It emphasizes the risks associated with common procedures, particularly those that are iatrogenic, meaning caused by medical intervention. The discussion highlights how understanding these risks can help in early detection and management, ultimately improving reproductive success and animal welfare. The article also provides insights into best practices to minimize complications, ensuring safer procedures and better outcomes for breeding horses.
Adverse Effects of Antimicrobial Drugs Use in Horses.
The Veterinary clinics of North America. Equine practice    October 6, 2025   Volume 41, Issue 3 633-651 doi: 10.1016/j.cveq.2025.08.010
Gomez DE, Johnson JP.Antimicrobial drug therapy in horses can lead to adverse effects across multiple body systems, with specific age groups, such as foals, at particular risk. Certain antimicrobial drugs, such as penicillins, aminoglycosides, macrolides, tetracyclines, and trimethoprim-sulfonamide combinations, are commonly implicated. This review explores the mechanisms behind these adverse reactions, emphasizing the importance of judicious antimicrobial drug use. This review also underscores the need for a centralized pharmacovigilance system to improve drug safety and adverse event reporting for veterinary med...
Complications of the Recumbent Horse: Diagnosis and Management.
The Veterinary clinics of North America. Equine practice    September 30, 2025   Volume 41, Issue 3 619-632 doi: 10.1016/j.cveq.2025.08.009
Delvescovo B, Bouton J.This issue focuses on the potential complications caused by prolonged recumbency in horses. It discusses how managing a recumbent horse involves treating the primary illness while also preventing and addressing secondary issues that can arise from recumbency itself. The authors explore the underlying pathophysiology of these complications, along with strategies for prevention and treatment. By understanding these aspects, veterinarians can improve care and outcomes for horses that are immobilized for extended periods. The issue provides insights into the most common complications and emphasize...
Complications in Wound Management.
The Veterinary clinics of North America. Equine practice    September 30, 2025   Volume 41, Issue 3 563-578 doi: 10.1016/j.cveq.2025.08.006
Morales Yñiguez FJ, Leise BS.Over 25% of all emergencies are classified as wounds, making them the most common health conditions treated by veterinarians. While equine wounds may heal with minimal intervention, many complications associated with wound management can occur, thereby delaying wound healing and leading to chronic non-healing wounds. Wounds should be closed primarily when possible; however, numerous factors influence the risk of complications. Infection and biofilm production are common causes of delayed wound healing. Other causes of non-healing wounds include the presence of foreign material, sequestrum form...
Accidents, Injuries, and Complications in Equine Sports Medicine Practice.
The Veterinary clinics of North America. Equine practice    September 26, 2025   Volume 41, Issue 3 529-543 doi: 10.1016/j.cveq.2025.08.001
Allen TS, Johnson S.The physical stresses on equine athletes are unique and differ across various disciplines. Recognizing these differences is essential for early detection of injuries and effective management of the competition horse's health. Equine sports medicine involves specific challenges and risks that can be reduced through proper care, careful attention to technique, and a deep understanding of the demands of each sport. Proper training, regular monitoring, and sport-specific expertise are crucial in preventing injuries and ensuring optimal performance. By focusing on these aspects, veterinarians and t...
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