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American journal of veterinary research2005; 63(1); 19-27; doi: 10.2460/ajvr.2002.63.19

Effect of oral administration of electrolyte pastes on rehydration of horses.

Abstract: To determine whether the composition of electrolyte pastes formulated for oral administration influences voluntary water intake (WI) by horses recovering from furosemide-induced dehydration. Methods: 6 horses. Methods: Voluntary WI, body weight, and blood and urine constituents were measured before and after induction of dehydration by furosemide administration and overnight withholding of water; these same variables also were measured during a 36-hour rehydration period. Each horse was evaluated 4 times with random application of 4 treatments (electrolyte pastes) that provided 0.5 g of KCl/kg of body weight, 0.5 g of NaCl/kg, 0.25 g of NaCl and 0.25 g of KCl/kg, or no electrolytes (control treatment). Electrolyte pastes were administered 3 times (4, 8, and 12 hours after start of the rehydration period). Results: Administration of all electrolyte pastes resulted in significantly greater voluntarily WI, compared with the control treatment, and was accompanied by significantly greater recovery of body weight when NaCl was a component of the paste. Administration of NaCl and NaCl-KCl pastes tended to produce a state of transient hyperhydration; however, electrolyte administration also resulted in significantly greater urine production and electrolyte excretion during the final 24 hours of the rehydration period. Adverse effects of oral administration of hypertonic electrolyte pastes were not observed. Conclusions: Oral administration of electrolyte pastes to dehydrated horses increases voluntary WI and improves rehydration during the rehydration period. Rehydration is more rapid and complete when NaCl is a component of the electrolyte paste.
Publication Date: 2005-10-07 PubMed ID: 16206775DOI: 10.2460/ajvr.2002.63.19Google Scholar: Lookup
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  • Journal Article
  • Research Support
  • Non-U.S. Gov't

Summary

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The research article investigates how different electrolyte pastes given orally affect the rehydration process in horses suffering from dehydration due to furosemide, a diuretic drug. The outcome indicates that all electrolyte pastes tested improved voluntary water consumption and recovery of body weight while Sodium Chloride (NaCl) when part of the paste, offered the best hydration results.

Research Methodology

  • The research was conducted using six horses.
  • The applied procedures involved measuring voluntary water intake (WI), body weight, and the constituents of blood and urine, before and after inducing dehydration. This was done using the administration of the diuretic drug, furosemide, and withholding water overnight.
  • Similar variables were also measured during a 36-hour rehydration period.
  • Each horse was given four separate treatments non-specifically, these treatments were four different electrolyte pastes. These pastes provided either 0.5 g of KCl/kg of body weight, 0.5 g of NaCl/kg, 0.25 g of NaCl and 0.25 g of KCl/kg, or included no electrolytes (control treatment).
  • The electrolyte pastes were administered three times at 4, 8, and 12 hours after the start of the rehydration period.

Research Findings

  • Voluntary WI was significantly higher with all electrolyte pastes compared to the control treatment.
  • Horse recovery of body weight was significantly better when NaCl was a component of the electrolyte paste.
  • The usage of NaCl and combined NaCl-KCl pastes seemed to foster temporary hyperhydration.
  • Increased urine production and electrolyte excretion during the final 24 hours of the rehydration period was observed in horses that received the electrolyte pastes.
  • No adverse effects were detected from oral administration of hypertonic electrolyte pastes.

Conclusions

  • Oral administration of electrolyte pastes to dehydrated horses can lead to improved rehydration through increased voluntary WI.
  • Rehydration is more efficient and complete when NaCl is a component of the electrolyte paste. This finding suggests electrolyte pastes that contain NaCl could be more effective for managing dehydration in horses.

Cite This Article

APA
Schott HC, Axiak SM, Woody KA, Eberhart SW. (2005). Effect of oral administration of electrolyte pastes on rehydration of horses. Am J Vet Res, 63(1), 19-27. https://doi.org/10.2460/ajvr.2002.63.19

Publication

ISSN: 0002-9645
NlmUniqueID: 0375011
Country: United States
Language: English
Volume: 63
Issue: 1
Pages: 19-27

Researcher Affiliations

Schott, Harold C
  • Department of Large Animal Clinical Sciences, College of Veterinary Medicine, Michigan State University, East Lansing, MI 48824-1314, USA.
Axiak, Shannon M
    Woody, Kristina A
      Eberhart, Susan W

        MeSH Terms

        • Animals
        • Dehydration / chemically induced
        • Dehydration / drug therapy
        • Dehydration / veterinary
        • Diuretics
        • Dosage Forms
        • Drinking / drug effects
        • Electrolytes / administration & dosage
        • Female
        • Furosemide
        • Horse Diseases / drug therapy
        • Horses
        • Male
        • Potassium Chloride / administration & dosage
        • Sodium Chloride / administration & dosage
        • Time Factors

        Citations

        This article has been cited 3 times.
        1. Lindinger MI. Oral Electrolyte and Water Supplementation in Horses. Vet Sci 2022 Nov 10;9(11).
          doi: 10.3390/vetsci9110626pubmed: 36356103google scholar: lookup
        2. Walker WT, Callan RJ, Hill AE, Tisher KB. Effects of oral powder electrolyte administration on packed cell volume, plasma chemistry parameters, and incidence of colic in horses participating in a 6-day 162-km trail ride. Can Vet J 2014 Aug;55(8):765-71.
          pubmed: 25082992
        3. Alshut F, Venner M, Martinsson G, Vervuert I. The effects of feeding sodium chloride pellets on the gastric mucosa, acid-base, and mineral status in exercising horses. J Vet Intern Med 2023 Nov-Dec;37(6):2552-2561.
          doi: 10.1111/jvim.16851pubmed: 37776109google scholar: lookup