[Effect of ultraviolet ray-irradiated autogenous blood on hematological indices in horses].
Abstract: Comparative clinical and experimental investigations were carried out on 18 clinically normal horses. It was found that the single transfusion of in vitro UV-treated autogenous blood, following a previously described method, was tolerated well by horses and did not lead to any deviations from the normal indices. Under the effect of the treated blood there was an increase in the hemoglobin content, rise in the erythrocyte and leukocyte count with slightly expressed hyperleukocytosis and weak neutrophilia (simple regeneration of the blood). The sedimentation of erythrocytes also showed higher rates as early as the first hour following the autohemotransfusion, remaining at the attained level up to the fourth day, while on the sixth day it again came back to the initial value. The contents of calcium and inorganic phosphorus rose, showing a slightly expressed shift to the physiologic level without reaching it. The changes in the phagocytic activity of the blood showed that the autohemotransfusion stimulates phagocytosis. Along with these effects the bacteriostatic titer of the blood, as recorded with the use of the anthrax bacillus as early as the first hour, and likewise favourably affected, the highest titers being observed at the 24th and 48th hour.
Publication Date: 1976-01-01 PubMed ID: 1030866
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- Comparative Study
- English Abstract
- Journal Article
Summary
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This research involved an experimental study on 18 clinically healthy horses to determine the impact of transfusing ultraviolet ray-irradiated autogenous blood. Results indicated increased hemoglobin levels, blood cell count, and stimulated phagocytosis alongside risen calcium and inorganic phosphorus levels.
Experiment Setup
- The experimental process involved a study conducted on 18 horses that were clinically healthy.
- The horses were administered a single transfusion of ultraviolet ray-irradiated autogenous blood, a method previously described.
Observations and Findings
- According to this study, this procedure was well-tolerated by the horses, and the results did not deviate from the normal
- The transfusion led to an increase in the hemoglobin content
- A rise was also noticed in the erythrocyte and leukocyte count, illustrating minor hyperleukocytosis and weak neutrophilia, accrediting to the simple regeneration of blood.
- The sedimentation rate of erythrocytes escalated within the first hour post-transfusion, maintaining a consistent level until the fourth day, and returning to the initial values by the sixth day.
Changes in Physiological Components of Blood
- Noticeable changes included increased calcium and inorganic phosphorus levels, suggesting a minor shift towards the physiological level, but without reaching it wholly.
Impact on Blood Activity
- The phagocytic activity, which refers to the ability of certain cells to engulf, destroy and ingest foreign substances or particles, of the blood also showed positive changes. This indicates that this transfusion method successfully stimulates phagocytosis.
Bacteriostatic Titer and Blood Activity
- The research also measured the bacteriostatic titer of the blood, using the anthrax bacillus as a marker. The results revealed that transfusing ultraviolet ray-irradiated autogenous blood showed a favorable effect, with the maximum titers noted at the 24th and 48th hour mark.
Cite This Article
APA
Bodurov N, Filipov Zh.
(1976).
[Effect of ultraviolet ray-irradiated autogenous blood on hematological indices in horses].
Vet Med Nauki, 13(10), 11-19.
Publication
Researcher Affiliations
MeSH Terms
- Animals
- Blood / radiation effects
- Blood Bactericidal Activity / radiation effects
- Blood Cells / radiation effects
- Blood Sedimentation
- Blood Transfusion, Autologous / veterinary
- Calcium / blood
- Hemoglobins / analysis
- Horses / blood
- Leukocytes / immunology
- Leukocytes / radiation effects
- Phagocytosis / radiation effects
- Phosphorus / blood
- Time Factors
- Ultraviolet Rays
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