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Home / Equine Research Bank / J Equine Sci / Effects of a joint supplement whose main components are resv...
Journal of equine science2016; 27(1); 19-22; doi: 10.1294/jes.27.19

Effects of a joint supplement whose main components are resveratrol and hyaluronic acid on some biochemical parameters in aged lame horses.

Abstract: This study aimed to evaluate the effects of a supplement that contains resveratrol and hyaluronic acid (RH supplement) in aged lame horses. A total of 16 horses of both sexes, aged between 15 and 22 years, weighing between 350-450 kg and showing lameness due to arthritis of the knee, hock, stifle, and fetlock joints and stiffness owing to ageing were used for the study. They comprised eight horses that were administered the RH supplement for three weeks and eight others that served as controls and were given only a Saccharomyces cerevisiae yeast strain used as carrier in the supplement. Blood samples were collected from each horse before supplementation (week 0) and at weekly intervals for the three weeks of the experiment. Biochemical parameters including creatine kinase, aspartate aminotransferase, urea, glucose, total cholesterol, sodium, potassium, chloride, and calcium were measured by standard methods. There was a significant (P˂0.05) reduction in values of creatine kinase and glucose in the horses administered the RH supplement. It was concluded that the RH supplement may reduce the level of these biochemical parameters and their deleterious effects especially during ageing in horses.
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Publication Date: 2016-04-12 PubMed ID: 27073333PubMed Central: PMC4828249DOI: 10.1294/jes.27.19Google Scholar: Lookup
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  • Journal Article

Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

This research article explores how a supplement composed primarily of resveratrol and hyaluronic acid can affect biochemical parameters in older horses with lameness.

Study Purpose and Design

  • The research aimed to test the effects of a joint supplement containing two key ingredients: resveratrol, an antioxidant, and hyaluronic acid, a substance beneficial for joint health.
  • The study was inspired by the need to manage degenerative joint conditions in older, lame horses characterized by arthritis and stiffness due to ageing.
  • In the study, 16 horses between the ages of 15 and 22, both male and female, were chosen. All horses presented lameness due to arthritis in various joints and stiffness.

Methodology

  • For the experiment, the horses were divided into two groups. One group of eight horses was given the resveratrol and hyaluronic acid (RH) supplement for three weeks.
  • The other group, also consisting of eight horses, served as the control group and received only a Saccharomyces cerevisiae yeast strain, which was used as a carrier in the supplement.
  • Blood samples were taken from each horse before the supplement administration started (week 0) and then at weekly intervals during the experiment.

Measures and Findings

  • The researchers measured a range of biochemical parameters in the horses’ blood, including creatine kinase, aspartate aminotransferase, urea, glucose, total cholesterol, sodium, potassium, chloride, and calcium. These parameters were evaluated using standard laboratory methods.
  • Following analysis, the research found a significant reduction in creatine kinase and glucose levels in the horses that had been given the RH supplement when compared to the control group.

Conclusions

  • The study concluded that the joint supplement with resveratrol and hyaluronic acid is capable of lowering specific biochemical parameters, especially important for senior horses.
  • The results suggest the supplement could potentially mitigate the harmful effects that these parameters can exert during ageing in horses, particularly in relation to joint health.

Cite This Article

APA
Ememe MU, Abdullahi US, Sackey AK, Ayo JO, Mshelia WP, Edeh RE. (2016). Effects of a joint supplement whose main components are resveratrol and hyaluronic acid on some biochemical parameters in aged lame horses. J Equine Sci, 27(1), 19-22. https://doi.org/10.1294/jes.27.19

Publication

Journal of equine science
ISSN: 1340-3516
NlmUniqueID: 9503751
Country: Japan
Language: English
Volume: 27
Issue: 1
Pages: 19-22

Researcher Affiliations

Ememe, Mary U
  • Department of Veterinary Medicine, Ahmadu Bello University, Zaria, Nigeria.
Abdullahi, Usman S
  • Department of Veterinary Medicine, Ahmadu Bello University, Zaria, Nigeria.
Sackey, Anthony K B
  • Department of Veterinary Medicine, Ahmadu Bello University, Zaria, Nigeria.
Ayo, Joseph O
  • Department of Veterinary Physiology, Ahmadu Bello University, Zaria, Nigeria.
Mshelia, Wayuta P
  • Department of Veterinary Medicine, Ahmadu Bello University, Zaria, Nigeria.
Edeh, Richard E
  • Department of Veterinary Medicine, Ahmadu Bello University, Zaria, Nigeria.

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Citations

This article has been cited 1 times.
  1. Martin LM, Johnson PJ, Amorim JR, DeClue AE. Effects of Orally Administered Resveratrol on TNF, IL-1β, Leukocyte Phagocytic Activity and Oxidative Burst Function in Horses: A Prospective, Randomized, Double-Blinded, Placebo-Controlled Study. Int J Mol Sci 2020 Feb 20;21(4).
    doi: 10.3390/ijms21041453pubmed: 32093379google scholar: lookup
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