Effects of induced alkalosis on performance in thoroughbreds during a 1,600-m race.
Abstract: There is considerable debate regarding the ergogenic effects of sodium bicarbonate (NaHCO3) on racing performance in horses. Anecdotal evidence suggests that NaHCO3 improves performance by increasing the buffering capacity of the blood and delaying the onset of hydrogen ion-induced fatigue. In a cross-over study, 16 Thoroughbred racehorses were given an aqueous solution of NaHCO3 (0.4 g/kg in 1 litre H2O) or a control treatment (1 litre H2O) before a 1600-m race. Treatments were administered 3 h before the race, which was the time to peak buffering capacity (2.5-3.0 h) determined in a separate study. Before the race, there was a significant increase in venous HCO3- and pH in the NaHCO3-treated horses. After the race, there was a significant increase in venous blood pH and lactate in the NaHCO3-treated horses. Collectively, the data suggest an improved buffering capacity of the blood after NaHCO3 treatment. However, there was no change in race times or venous partial pressure of carbon dioxide. Therefore, the administration of NaHCO3 provided no ergogenic benefit to horses competing in a 1,600-m race.
Publication Date: 1992-03-01 PubMed ID: 1316267DOI: 10.1111/j.2042-3306.1992.tb02790.xGoogle Scholar: Lookup
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- Journal Article
- Research Support
- Non-U.S. Gov't
Summary
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The study examines the effect of sodium bicarbonate (NaHCO3) on the performance of thoroughbreds in a 1600-m race and concludes that it offers no significant improvement.
Study Design and Method
- The research was a cross-over study involving 16 Thoroughbred racehorses
- The selected horses were administered an aqueous solution of sodium bicarbonate or a control treatment before the race.
- The researchers administered the treatments about 3 hours before the race, a timeframe chosen based on a separate study that determined this to be the peak time for buffering capacity.
Treatment and Measurements
- The horses were given either a NaHCO3 solution (0.4 g/kg in a 1-liter H2O) or a control treatment (only 1 liter H2O)
- Physiological parameters such as venous HCO3-, pH, and lactate levels were measured before and after the race.
Results and Findings
- Before the start of the race, a significant increase in venous HCO3- and pH levels was observed in horses treated with NaHCO3.
- A similar increase was also noted in venous blood pH and lactate levels after the race in the NaHCO3 treated horses.
- These findings suggest that the blood’s buffering capacity was increased by the NaHCO3 treatment.
Conclusion and Implications
- Despite the apparent increase in blood buffering, there was no noticeable improvement in the race times for horses treated with NaHCO3.
- There was also no change observed in the venous partial pressure of carbon dioxide.
- The key implication is that while sodium bicarbonate seemingly increased the blood’s buffering capacity in Thoroughbred racehorses, it did not translate into any performance benefit in a 1,600-m race.
Cite This Article
APA
Harkins JD, Kamerling SG.
(1992).
Effects of induced alkalosis on performance in thoroughbreds during a 1,600-m race.
Equine Vet J, 24(2), 94-98.
https://doi.org/10.1111/j.2042-3306.1992.tb02790.x Publication
Researcher Affiliations
- Department of Veterinary Physiology, Pharmacology and Toxicology, School of Veterinary Medicine, Louisiana State University, Baton Rouge 70803.
MeSH Terms
- Acid-Base Equilibrium
- Alkalosis / blood
- Alkalosis / physiopathology
- Alkalosis / veterinary
- Animals
- Bicarbonates / blood
- Bicarbonates / pharmacology
- Breeding
- Buffers
- Carbon Dioxide / blood
- Doping in Sports
- Female
- Horse Diseases / blood
- Horse Diseases / physiopathology
- Horses
- Humidity
- Hydrogen-Ion Concentration
- Lactates / blood
- Male
- Physical Exertion / drug effects
- Sodium / pharmacology
- Sodium Bicarbonate
- Temperature
- Time Factors
- Wind
Citations
This article has been cited 2 times.- Geng W, Long SL, Chang YJ, Saxton AM, Joyce SA, Lin J. Evaluation of bile salt hydrolase inhibitor efficacy for modulating host bile profile and physiology using a chicken model system. Sci Rep 2020 Mar 18;10(1):4941.
- Dirikolu L, Waller P, Waguespack ML, Andrews FM, Keowen ML, Gaunt SD. The effect of sodium bicarbonate and validation of beckman coulter AU680 analyzers for measuring total carbon dioxide (TCO(2)) concentrations in horse serum. Vet Med Sci 2017 Nov;3(4):263-269.
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