Effects of training on phagocytic and oxidative metabolism of peripheral neutrophils in horses exercised in the aerobic-anaerobic transition area.
Abstract: Using simple techniques, the neutrophil function, in its phagocytosis and oxidative metabolism stages, was evaluated in horses. This was done before and after moderate exercise at the aerobic-anaerobic threshold (standardized heart rate 150 beats/min and lactate level of 3.07 +/- 0.21 mmol/L). The objective was to determine whether regular training and moderate exercise improved the neutrophil function. A group of 19 horses was used; 11 of these were untrained and the remainder trained for national jumping events. The exercise test consisted of a 5 min trot followed by a 3 min gallop on a long lunge. Blood samples were taken for analysis before, immediately after and 15 min after exercise. The results showed that (a) there is a difference in the internalization of particles (PI, PP and PE) by neutrophils from trained and untrained horses at a single time point during active recovery, and PP is higher in trained horses immediately after exercise; and (b) oxidative metabolism is significantly lower in untrained animals before and 1 min after exercise. The moderate exercise at the aerobic-anaerobic threshold did not have any influence on the peripheral blood neutrophil function of the phagocytosis and oxidative metabolism of particles.
Publication Date: 2005-02-26 PubMed ID: 15730139DOI: 10.1023/b:verc.0000047494.29439.23Google Scholar: Lookup
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- Journal Article
Summary
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The research evaluates the function of neutrophils in horses both before and after moderate exercise at the aerobic-anaerobic transition area and finds that regular training improves the neutrophil function.
Objective and Methods of the Research
- The research aimed at examining the role regular training and moderate exercise at the aerobic-anaerobic threshold might have on the function of neutrophils, a type of white blood cell, in horses.
- A group of 19 horses were part of this study, out of which, 11 were untrained while the rest were trained for national jumping events.
- As part of the study, these horses were made to perform a 5 min trot followed by a 3 min gallop on a long lunge.
- The researchers evaluated the function of neutrophils in its phagocytosis and oxidative metabolism stages in these horses both before and after the exercise regimen.
- Blood samples were taken and analyzed before, immediately after, and 15 minutes post exercise.
Results of the Research
- The results revealed a difference in the neutrophils’ ability to internalize the particles (identified as PI, PP and PE) between the trained and untrained horses during active recovery.
- The trained horses displayed a higher degree of internalization of particle PP immediately following exercise.
- Unveiling that the oxidative metabolism, the process by which the body produces energy to fuel its functions, was significantly lower in untrained horses before and 1 minute post exercise.
- However, moderate exercise at the aerobic-anaerobic threshold did not appear to influence the peripheral blood neutrophil function in terms of the phagocytosis and oxidative metabolism of particles.
- The conclusion therefore indicates that regular training improves neutrophil function, which could enhance the overall immunity and fitness of the horses.
Cite This Article
APA
Escribano BM, Castejón FM, Vivo R, Santisteban R, Agüera EI, Rubio MD.
(2005).
Effects of training on phagocytic and oxidative metabolism of peripheral neutrophils in horses exercised in the aerobic-anaerobic transition area.
Vet Res Commun, 29(2), 149-158.
https://doi.org/10.1023/b:verc.0000047494.29439.23 Publication
Researcher Affiliations
- Department of Cell Biology, Physiology and Immunology (Physiology) University of Cordóba, edif: C-1, Campus Universitario de Rabanales, 14071-Cordóba, Spain. am1esdub@uco.es
MeSH Terms
- Anaerobic Threshold / physiology
- Animals
- Horses / blood
- Horses / physiology
- Male
- Neutrophils / physiology
- Oxygen Consumption / physiology
- Phagocytosis / physiology
- Physical Conditioning, Animal / physiology
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Citations
This article has been cited 2 times.- Górniak W, Cholewińska P, Szeligowska N, Wołoszyńska M, Soroko M, Czyż K. Effect of Intense Exercise on the Level of Bacteroidetes and Firmicutes Phyla in the Digestive System of Thoroughbred Racehorses.. Animals (Basel) 2021 Jan 24;11(2).
- Sako T, Urabe S, Kusaba A, Kimura N, Yoshimura I, Tazaki H, Imai S, Ono K, Arai T. Comparison of plasma metabolite concentrations and lactate dehydrogenase activity in dogs, cats, horses, cattle and sheep.. Vet Res Commun 2007 May;31(4):413-7.
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