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The Veterinary record1985; 116(13); 343-345; doi: 10.1136/vr.116.13.343

Efficacy of ivermectin against Dictyocaulus arnfieldi in ponies.

Abstract: The efficacy of orally administered ivermectin against induced Dictyocaulus arnfieldi infection was evaluated in a controlled study comprising 12 yearling ponies. Treatment with ivermectin paste, at a dose rate of 200 micrograms/kg bodyweight orally once, was 100 per cent effective against both adult and immature or inhibited stages of the horse lungworm. Similar control of second and third instars of Gastrophilus intestinalis was observed and no nematode eggs were present in faeces from seven to 15 days after treatment when the study was terminated.
Publication Date: 1985-03-30 PubMed ID: 3159145DOI: 10.1136/vr.116.13.343Google Scholar: Lookup
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  • Journal Article

Summary

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This research article investigates the effectiveness of orally administered ivermectin, a medication commonly used to treat parasitic diseases, against a specific species of lungworm in horses. The results suggest that the medication can eliminate both adult and immature life stages of these parasites.

Study Overview

The study was a controlled experiment that aimed to test the effectiveness of ivermectin (administered orally) against the Dictyocaulus arnfieldi species of lungworm, which commonly affect horses. The study used 12 yearling ponies, all of whom were intentionally infected with the lungworm.

  • The ponies were each given a single dose of ivermectin paste to test its efficacy.
  • A dose rate of 200 micrograms per kilogram of body weight was used for the treatment.

Experimental Results and Findings

The study found that ivermectin was very effective against the Dictyocaulus arnfieldi infection.

  • The treatment was 100% effective against both mature (adult) and immature (inhibited stages) of the parasite.
  • Furthermore, the medication also demonstrated a similar degree of control against second and third stages larvae (or instars) of Gastrophilus intestinalis, another parasite that commonly affects horses.
  • In addition, the researchers did not find any nematode eggs in the feces samples collected from the ponies between seven and 15 days after the treatment, thereby confirming the effectiveness of the drug.

Research Conclusion

In conclusion, this study raises compelling evidence about the effectiveness of ivermectin against Dictyocaulus arnfieldi infections in horses. The medication appears to eliminate these parasites in all of their life stages, suggesting its potential as an effective treatment for lungworm infections in equines.

Cite This Article

APA
Britt DP, Preston JM. (1985). Efficacy of ivermectin against Dictyocaulus arnfieldi in ponies. Vet Rec, 116(13), 343-345. https://doi.org/10.1136/vr.116.13.343

Publication

ISSN: 0042-4900
NlmUniqueID: 0031164
Country: England
Language: English
Volume: 116
Issue: 13
Pages: 343-345

Researcher Affiliations

Britt, D P
    Preston, J M

      MeSH Terms

      • Administration, Oral
      • Animals
      • Antinematodal Agents / therapeutic use
      • Dictyocaulus / isolation & purification
      • Dictyocaulus Infections / drug therapy
      • Dictyocaulus Infections / parasitology
      • Diptera / isolation & purification
      • Drug Evaluation, Preclinical / veterinary
      • Feces / parasitology
      • Horse Diseases / drug therapy
      • Horse Diseases / parasitology
      • Horses
      • Ivermectin
      • Lactones / therapeutic use
      • Larva / isolation & purification
      • Lung / parasitology
      • Male
      • Parasite Egg Count / veterinary
      • Time Factors

      Citations

      This article has been cited 2 times.
      1. Gernandt N, Wentzel C, van Staden D, Liebenberg W, Lemmer HJR, Gerber M. Therapeutic and Formulation Advances of Ivermectin in Veterinary and Human Medicine. Pharmaceutics 2025 Oct 25;17(11).
        doi: 10.3390/pharmaceutics17111384pubmed: 41304722google scholar: lookup
      2. Bell RJ, Holste JE. Efficacy of ivermectin oral liquid for horses. Can Vet J 1990 Jul;31(7):519-21.
        pubmed: 17423630