Efficacy of ivermectin against Dictyocaulus arnfieldi in ponies.
- Journal Article
Summary
This research article investigates the effectiveness of orally administered ivermectin, a medication commonly used to treat parasitic diseases, against a specific species of lungworm in horses. The results suggest that the medication can eliminate both adult and immature life stages of these parasites.
Study Overview
The study was a controlled experiment that aimed to test the effectiveness of ivermectin (administered orally) against the Dictyocaulus arnfieldi species of lungworm, which commonly affect horses. The study used 12 yearling ponies, all of whom were intentionally infected with the lungworm.
- The ponies were each given a single dose of ivermectin paste to test its efficacy.
- A dose rate of 200 micrograms per kilogram of body weight was used for the treatment.
Experimental Results and Findings
The study found that ivermectin was very effective against the Dictyocaulus arnfieldi infection.
- The treatment was 100% effective against both mature (adult) and immature (inhibited stages) of the parasite.
- Furthermore, the medication also demonstrated a similar degree of control against second and third stages larvae (or instars) of Gastrophilus intestinalis, another parasite that commonly affects horses.
- In addition, the researchers did not find any nematode eggs in the feces samples collected from the ponies between seven and 15 days after the treatment, thereby confirming the effectiveness of the drug.
Research Conclusion
In conclusion, this study raises compelling evidence about the effectiveness of ivermectin against Dictyocaulus arnfieldi infections in horses. The medication appears to eliminate these parasites in all of their life stages, suggesting its potential as an effective treatment for lungworm infections in equines.
Cite This Article
Publication
Researcher Affiliations
MeSH Terms
- Administration, Oral
- Animals
- Antinematodal Agents / therapeutic use
- Dictyocaulus / isolation & purification
- Dictyocaulus Infections / drug therapy
- Dictyocaulus Infections / parasitology
- Diptera / isolation & purification
- Drug Evaluation, Preclinical / veterinary
- Feces / parasitology
- Horse Diseases / drug therapy
- Horse Diseases / parasitology
- Horses
- Ivermectin
- Lactones / therapeutic use
- Larva / isolation & purification
- Lung / parasitology
- Male
- Parasite Egg Count / veterinary
- Time Factors
Citations
This article has been cited 2 times.- Gernandt N, Wentzel C, van Staden D, Liebenberg W, Lemmer HJR, Gerber M. Therapeutic and Formulation Advances of Ivermectin in Veterinary and Human Medicine. Pharmaceutics 2025 Oct 25;17(11).
- Bell RJ, Holste JE. Efficacy of ivermectin oral liquid for horses. Can Vet J 1990 Jul;31(7):519-21.