Electroencephalographic power spectrum analysis as a monitor of anesthetic depth in horses.
Abstract: Electroencephalographic (EEG) power spectrum analysis was performed in 18 conscious, adult horses for evaluation as control values for EEG data obtained during anesthesia. Computer-processed total amplitudes for the frequency range 0 to 32 Hz were mainly between 400 and 600 microV, with 80% spectral edge frequency between 16.6 and 32.5 Hz. The highest electrical activity was in the delta band (41.3 +/- 4.4% of total amplitude); there was a less pronounced activity in the beta (34.2 +/- 5.2%), theta (13.6 +/- 1.5%), and alpha (10.0 +/- 1.0%) bands. The applicability of EEG power spectrum analysis as a guide to depth of anesthesia was evaluated in four horses by comparing simultaneously recorded EEG data and clinical signs of anesthesia. Global changes in cerebrocortical electrical activity were detected with a single, monopolar (left frontoatlanto-occipital) EEG lead. Increasing depth of halothane anesthesia was accompanied by a pronounced shift in EEG activity from beta to theta and delta frequency bands, a decrease in 80% spectral edge frequency from 21.5 +/- 2.4 Hz to 12.6 +/- 2.2 Hz, a reduction in the beta/delta ratio of fractional amplitudes from 2.37 +/- 0.84 to 0.49 +/- 0.04, and a slight inconsistent increase in total amplitude from 96.1 +/- 37.3 microV to 185.5 +/- 53 microV. These results show that changes in the clinical signs of anesthetic depth in horses can be described numerically by use of EEG power spectrum analysis.
Publication Date: 1991-09-01 PubMed ID: 1962420DOI: 10.1111/j.1532-950x.1991.tb01284.xGoogle Scholar: Lookup
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Summary
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The research paper explores the use of Electroencephalographic (EEG) power spectrum analysis as a way to monitor the depth of anesthesia in horses. The findings show numerical changes in clinical signs of anesthetic depth, which can be measured using EEG power spectrum analysis.
Understanding EEG Power Spectrum Analysis
- The study uses Electroencephalographic (EEG) power spectrum analysis, a technique that tracks and analyses the electrical activity of the brain. This is done to evaluate its potential as a way to monitor the depth of anesthesia in horses.
- In order to establish a baseline, the EEG power spectrum analysis was first performed on 18 conscious adult horses. The data collected during these initial evaluations served as control values to compare with the EEG data obtained during the subsequent anesthesia.
Measuring Anesthetic Depth in Horses
- The applicability of EEG power spectrum analysis was further validated by comparing EEG data and clinical signs of anesthesia in four horses.
- A single, monopolar EEG lead was used to detect global changes in cerebrocortical electrical activity, representing the overall processing activity occurring in the brain during different depths of anesthesia.
Results and Findings
- The study found significant shifts in EEG activity from beta to theta and delta frequency bands as the depth of halothane anesthesia increased. Halothane is a type of general anesthetic used in veterinary medicine.
- Additionally, an observable decrease was noted in the 80% spectral edge frequency, and a reduction was seen in the beta/delta ratio of fractional amplitudes.
- Interestingly, there was a slight and inconsistent increase noted in the total amplitude of the EEG signal with increasing depth of anesthesia.
- The research concludes that EEG power spectrum analysis can offer a numeric descriptor of the changes observed in the clinical signs related to anesthetic depth in horses.
Cite This Article
APA
Otto K, Short CE.
(1991).
Electroencephalographic power spectrum analysis as a monitor of anesthetic depth in horses.
Vet Surg, 20(5), 362-371.
https://doi.org/10.1111/j.1532-950x.1991.tb01284.x Publication
Researcher Affiliations
- Department of Clinical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, New York 14850.
MeSH Terms
- Anesthesia, General / veterinary
- Animals
- Computers
- Electrodes / veterinary
- Electroencephalography / veterinary
- Evaluation Studies as Topic
- Horses / physiology
Citations
This article has been cited 6 times.- Dalla Costa FA, Gibson TJ, Oliveira SEO, Gregory NG, Coldebella A, Faucitano L, Ludtke CB, Buss LP, Dalla Costa OA. Evaluation of physical euthanasia for neonatal piglets on-farm. J Anim Sci 2020 Jul 1;98(7).
- Lacombe VA. Seizures in horses: diagnosis and classification. Vet Med (Auckl) 2015;6:301-308.
- Tünsmeyer J, Hopster K, Kästner SB. Clinical Use of a Multivariate Electroencephalogram (Narcotrend) for Assessment of Anesthetic Depth in Horses during Isoflurane-Xylazine Anesthesia. Front Vet Sci 2016;3:25.
- Williams DC, Brosnan RJ, Fletcher DJ, Aleman M, Holliday TA, Tharp B, Kass PH, LeCouteur RA, Steffey EP. Qualitative and Quantitative Characteristics of the Electroencephalogram in Normal Horses during Administration of Inhaled Anesthesia. J Vet Intern Med 2016 Jan-Feb;30(1):289-303.
- Lalonde-Robert V, Desgent S, Duss S, Vachon P. Electroencephalographic and physiologic changes after tricaine methanesulfonate immersion of African clawed frogs (Xenopus laevis). J Am Assoc Lab Anim Sci 2012;51(5):622-7.
- Mirra A, Hight D, Spadavecchia C, Levionnois OL. Spatio-temporal electroencephalographic power distribution in experimental pigs receiving propofol. PLoS One 2024;19(5):e0303146.
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