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The American journal of physiology1980; 238(2); H231-H236; doi: 10.1152/ajpheart.1980.238.2.H231

Energy and current requirements for ventricular defibrillation using trapezoidal waves.

Abstract: The threshold energy and current required for ventricular defibrillation was determined in dogs ranging in weight from 6.4 to 38 kg and in ponies ranging in weight from 40 to 101 kg. Trapezoidal waves, 10 ms in duration, with 10%, 50%, 70%, and 90% tilt were applied to transchest electrodes. For all values of tilt, the energy and current required increased with body weight. The energy dose (joules per kilogram of body weight) was higher for the heavier animals, whereas the current dose (peak amperes per kilogram of body weight) was essentially the same for dogs and ponies. In both species and for all four waveforms, the percent success increased with increasing energy and current dose. For all four waveforms and for both species, the threshold average current required for defibrillation was between 0.38 and 0.48 A/kg, indicating that average current may be a convenient unit to compare the efficacy of different waveforms.
Publication Date: 1980-02-01 PubMed ID: 7361919DOI: 10.1152/ajpheart.1980.238.2.H231Google Scholar: Lookup
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  • Journal Article
  • Research Support
  • U.S. Gov't
  • Non-P.H.S.
  • Research Support
  • U.S. Gov't
  • P.H.S.

Summary

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The research studies the amount of energy and current needed for ventricular defibrillation using trapezoidal waveforms in dogs and ponies of different weights. It was found that the energy and current required increased with body weight, and that the efficiency of defibrillation increased with more energy and current.

Research Background

  • The research focuses on ventricular defibrillation, a procedure used to treat life-threatening heart rhythms, and it looks specifically at the energy and current requirements for this procedure.
  • The study is conducted on dogs and ponies with varying weights, allowing the effects of body weight on energy and current requirements to be measured.
  • Trapezoidal waves of varying tilt values are applied to measure their impact on energy and current needs.

Research Findings

  • Across all tilt values, energy and current requirements increased with the weight of the subject. This suggests that larger animals require more energy and current for effective defibrillation.
  • The energy dose (measured in joules per kilogram of body weight) was found to be higher for heavier animals. In contrast, the current dose (measured in peak amperes per kilogram of body weight) remained consistent for dogs and ponies, regardless of their weight.
  • The research also observed that the success rate of ventricular defibrillation increased with higher energy and current doses. This implies that the procedure is more likely to succeed when more energy and current are applied.
  • For all waveforms and species, the threshold average current required for defibrillation was between 0.38 and 0.48 A/kg. This suggested that average current could be a useful unit for comparing the effectiveness of different waveforms in defibrillation.

Research Implications

  • The study’s results provide important insights into the energy and current needs for successful ventricular defibrillation for animals of varying sizes. This may help clinicians in determining the optimal requirements for defibrillation procedures in clinical settings.
  • The observation that average current may be an effective measure for comparing waveform effectiveness suggests a potential way to streamline and standardize evaluations of defibrillation protocol efficacies.

Cite This Article

APA
Geddes LA, Bourland JD, Tacker WA. (1980). Energy and current requirements for ventricular defibrillation using trapezoidal waves. Am J Physiol, 238(2), H231-H236. https://doi.org/10.1152/ajpheart.1980.238.2.H231

Publication

ISSN: 0002-9513
NlmUniqueID: 0370511
Country: United States
Language: English
Volume: 238
Issue: 2
Pages: H231-H236

Researcher Affiliations

Geddes, L A
    Bourland, J D
      Tacker, W A

        MeSH Terms

        • Animals
        • Biophysical Phenomena
        • Biophysics
        • Dogs
        • Electric Countershock
        • Electricity
        • Horses
        • Mathematics
        • Ventricular Fibrillation / therapy

        Citations

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