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The Cornell veterinarian1980; 70(1); 50-66;

Enflurane anesthesia in the pony: a comparative study between enflurane and halothane.

Abstract: Enflurane, a new volatile anesthetic agent, was compared with halothane as components of a commonly used clinical anesthetic regime in the pony. Enflurane provides satisfactory general anesthesia when administered at a maintenance concentration of approximately 1.5-2.5%, in combination with a 1:1 nitrous oxide-oxygen mixture. With both agents cardiac rhythm and pulse were stable, however significant arterial hypotension occurred, especially during and following induction, being anesthetic concentration dependent. Hypoventilation was induced by both agents, there being no significant quantitative difference in respiratory depression despite significantly lower respiratory rates with enflurane. Serum electrolytes and liver enzymes did not change significantly with either regime. Emergence from anesthesia was smooth, and significantly more rapid with enflurance. Post-anesthetic complications were not observed with either agent.
Publication Date: 1980-01-01 PubMed ID: 7379554
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  • Comparative Study
  • Journal Article

Summary

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This research article compares the use of two anesthetic agents, enflurane and halothane, in ponies. The study found both agents performed similarly, however, enflurane allowed for more rapid emergence from anesthesia.

Introduction to the Study

  • The study revolves around comparing two different anesthetics, enflurane and halothane, as components in a commonly used anesthetic regime for ponies.
  • Enflurane, a new volatile anesthetic agent, was tested and compared to the effects of the already established halothane.

Method of Anesthesia Administration

  • Both anesthetics were used in combination with a 1:1 nitrous oxide-oxygen mixture.
  • Enflurane was administered at a maintenance concentration of approximately 1.5-2.5%.
  • Close monitoring of both methods was conducted to record stable cardiac rhythm and pulse among the subjects.
  • Respiratory depression and arterial hypotension were measured in occurrences and severity, especially during and following induction.

Findings and Analysis

  • The study reported both agents induced hypotension, primarily during and post induction, as a direct dependence on the anesthetic concentration used.
  • Both agents caused hypoventilation, with no significant quantitative difference observed between them. However, significantly lower respiratory rates were recorded with enflurane.
  • Serum electrolytes and liver enzymes did not display significant changes under either regime, suggesting a limited impact on the internal systemic functions of the subject.

Post-Anesthesia Observations

  • The study noted that emergence from anesthesia was smooth with both agents, yet significantly faster with enflurane.
  • Little to no post-anesthetic complications were recorded for either anesthetic, suggesting a relatively safe profile for use with ponies.

Conclusion of the Study

  • The research concludes that enflurane and halothane are comparable when used as components of a typical clinical anesthetic regime in ponies.
  • However, with faster recovery times and statistically similar side effects, enflurane could possibly be the preferable choice.

Cite This Article

APA
Orsini JA, Taylor JI. (1980). Enflurane anesthesia in the pony: a comparative study between enflurane and halothane. Cornell Vet, 70(1), 50-66.

Publication

ISSN: 0010-8901
NlmUniqueID: 0074245
Country: United States
Language: English
Volume: 70
Issue: 1
Pages: 50-66

Researcher Affiliations

Orsini, J A
    Taylor, J I

      MeSH Terms

      • Anesthesia, Inhalation / veterinary
      • Animals
      • Electroencephalography / veterinary
      • Enflurane
      • Halothane
      • Heart Rate
      • Horses / physiology
      • Potassium / blood
      • Respiration

      Citations

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