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Home / Equine Research Bank / Can Vet J / Epidemiology of equine sarcoids in horses in western Canada.
The Canadian veterinary journal = La revue veterinaire canadienne2011; 51(10); 1103-1108;

Epidemiology of equine sarcoids in horses in western Canada.

Abstract: Sarcoids are the most common tumor of the equine skin but only 1 study describing the epidemiology of sarcoids in Canadian horses has been published. The records of 5 veterinary diagnostic laboratories in western Canada were searched to identify submissions of sarcoids from horses. The submission records and diagnostic reports of 802 separate submissions of equine sarcoids were reviewed for age, breed, and gender of the horse and the number, location, and clinical type of sarcoid. From these records, the 307 submissions to laboratories in Saskatchewan were compared to a reference group to test for breed and gender predisposition. Based on clinical history and lesion descriptions, 5 clinical types of sarcoids were identified. Horses of various ages and 23 equine breeds were affected; donkeys were over-represented. Polymerase chain reaction (PCR) for the bovine papillomavirus (BPV) DNA was performed on formalin-fixed paraffin-embedded tissues from a stratified subset of 96 of the different clinical types; BPV2 was present in 60 of 74 (81%) for which a PCR product was obtained. Unlike other areas in the world, in western Canada, equine sarcoids are most commonly associated with BPV type 2. Les sarcoïdes représentent le type de tumeur de la peau équine le plus fréquent mais seulement 1 étude décrivant l’épidémiologie des sarcoïdes chez les chevaux canadiens a été publiée. Une recherche a été réalisée dans les dossiers de 5 laboratoires diagnostiques vétérinaires de l’Ouest canadien afin d’identifier les soumissions de sarcoïdes provenant de chevaux. Les dossiers et les rapports diagnostiques de 802 soumissions séparées de sarcoïdes équins ont été examinés pour déterminer l’âge, la race et le sexe du cheval ainsi que le nombre, l’emplacement et le type clinique de sarcoïdes. À partir de ces dossiers, les 307 soumissions à des laboratoires en Saskatchewan ont été comparées à un groupe témoin pour réaliser des tests sur la race et la prédisposition des sexes. En se fondant sur les antécédents cliniques et les descriptions, 5 types cliniques ont été identifiés. Des chevaux d’âges divers et de 23 races équines ont été affectés; les ânes étaient surreprésentés. La réaction d’amplification en chaîne par la polymérase (ACP) pour l’ADN du papillomavirus bovin (BPV) a été effectuée sur des tissus fixés dans du formol et enrobés dans de la paraffine provenant d’un sous-groupe stratifié de 96 des différents types cliniques; le BPV2 était présent dans 60 de 74 (81 %) des échantillons pour lesquels un produit d’ACP a été obtenu. Contrairement aux autres régions du monde, dans l’Ouest canadien, les sarcoïdes équins sont le plus communément associés avec le BPV de type 2. (Traduit par Isabelle Vallières)
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Publication Date: 2011-01-05 PubMed ID: 21197201PubMed Central: PMC2942047
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  • Journal Article
  • Research Support
  • Non-U.S. Gov't

Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

This research examines the incidence and characteristics of sarcoids, a common equine skin tumor, in horses in Western Canada. It highlights that these tumors, contrary to findings in other regions, are most commonly associated with bovine papillomavirus type 2 (BPV2).

Objective and Methodology

  • The main objective of this research was to study the epidemiology, or incidence and distribution, of sarcoids in horses in Western Canada. This area had only one previous study on this topic.
  • To conduct this research, the team examined the records of five veterinary diagnostic laboratories in Western Canada.
  • The submission records and diagnostic reports from a total of 802 separate submissions were reviewed.
  • Information obtained included the horse’s age, breed, and gender, and the number, location, and clinical type of sarcoid.
  • The data from 307 submissions from laboratories in Saskatchewan were compared with a reference group to check for breed and gender predispositions.

Findings

  • Based on the clinical history and lesion descriptions, sarcoids were categorized into five clinical types.
  • The study found that horses of various ages and of 23 different equine breeds were affected by these tumors.
  • The records showed that donkeys were over-represented in the number of cases.
  • A polymerase chain reaction (PCR) test for bovine papillomavirus (BPV) DNA was performed on tissues from a subset of 96 horses showing different clinical types.
  • The results revealed that BPV2 was present in 60 out of 74 (81%) of samples for which a PCR product was obtained.

Conclusion

  • The study concluded that, unlike other areas in the world, equine sarcoids in Western Canada are most commonly associated with bovine papillomavirus type 2 (BPV2).

Cite This Article

APA
Wobeser BK, Davies JL, Hill JE, Jackson ML, Kidney BA, Mayer MN, Townsend HG, Allen AL. (2011). Epidemiology of equine sarcoids in horses in western Canada. Can Vet J, 51(10), 1103-1108.

Publication

The Canadian veterinary journal = La revue veterinaire canadienne
ISSN: 0008-5286
NlmUniqueID: 0004653
Country: Canada
Language: English
Volume: 51
Issue: 10
Pages: 1103-1108

Researcher Affiliations

Wobeser, Bruce K
  • Department of Veterinary Pathology, University of Saskatchewan, Canada. bruce.wobeser@usask.ca
Davies, Jennifer L
    Hill, Janet E
      Jackson, Marion L
        Kidney, Beverly A
          Mayer, Monique N
            Townsend, Hugh G G
              Allen, Andrew L

                MeSH Terms

                • Age Factors
                • Animals
                • Bovine papillomavirus 1 / isolation & purification
                • Breeding
                • Canada / epidemiology
                • Female
                • Genetic Predisposition to Disease
                • Horse Diseases / epidemiology
                • Horse Diseases / genetics
                • Horse Diseases / virology
                • Horses
                • Male
                • Papillomavirus Infections / epidemiology
                • Papillomavirus Infections / genetics
                • Papillomavirus Infections / veterinary
                • Papillomavirus Infections / virology
                • Polymerase Chain Reaction / veterinary
                • Sex Factors
                • Skin Neoplasms / epidemiology
                • Skin Neoplasms / genetics
                • Skin Neoplasms / veterinary
                • Skin Neoplasms / virology

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                Citations

                This article has been cited 6 times.
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                3. Munday JS, Orbell G, Fairley RA, Hardcastle M, Vaatstra B. Evidence from a Series of 104 Equine Sarcoids Suggests That Most Sarcoids in New Zealand Are Caused by Bovine Papillomavirus Type 2, although Both BPV1 and BPV2 DNA Are Detectable in around 10% of Sarcoids.. Animals (Basel) 2021 Oct 29;11(11).
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