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Home / Equine Research Bank / Braz J Microbiol / Equidae pythiosis in Brazil and the world: a systematic revi...
Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology]2024; 55(3); 2969-2981; doi: 10.1007/s42770-024-01435-6

Equidae pythiosis in Brazil and the world: a systematic review of the last 63 years (1960-2023).

Abstract: This systematic review compiles reports of clinical pythiosis in horses, mules and donkeys from 1960 to 2023 worldwide, focusing on Brazil. We searched databases and included 71 articles detailing clinical characteristics, geographic distribution, epidemiology, diagnostic methods, therapies, and outcomes. The results showed that publications on equine pythiosis have significantly increased since 2010. Brazil reported the highest incidence, comprising 55% of cases, predominantly in the southern, northeastern, and central-western regions during summer and autumn. Cutaneous pythiosis was the most prevalent form, generally presenting as single lesions in the appendicular region, and affected females more than males. Diagnosis typically involved histopathology, used alone or with other methods. Various treatments have been employed, with surgery, often combined with chemotherapy and immunotherapy, being the most common. Notably, 80.84% of treated animals recovered, highlighting the effectiveness of these therapies in enhancing survival rates. The limitations of the study included the lack of data in published case reports, which made it difficult to collect and calculate epidemiological data. Additionally, we recognize that pythiosis in Brazil is underreported, since this disease does not have mandatory notification and several cases are not registered and/or reported in the literature. Lastly, it is hypothesized that equid pythiosis may be more widespread than currently known, and its real occurrence in Brazil remains uncertain.
© 2024. The Author(s) under exclusive licence to Sociedade Brasileira de Microbiologia.
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Publication Date: 2024-07-05 PubMed ID: 38967702PubMed Central: PMC11405592DOI: 10.1007/s42770-024-01435-6Google Scholar: Lookup
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  • Journal Article
  • Systematic Review

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APA
Pereira DIB, Botton SA, Ianiski LB, Braga CQ, Maciel AF, Melo LG, Zambrano CG, Bruhn FRP, Santurio JM. (2024). Equidae pythiosis in Brazil and the world: a systematic review of the last 63 years (1960-2023). Braz J Microbiol, 55(3), 2969-2981. https://doi.org/10.1007/s42770-024-01435-6

Publication

Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology]
ISSN: 1678-4405
NlmUniqueID: 101095924
Country: Brazil
Language: English
Volume: 55
Issue: 3
Pages: 2969-2981

Researcher Affiliations

Pereira, Daniela Isabel Brayer
  • Instituto de Biologia, Departamento de Microbiologia e Parasitologia, Laboratório de Micologia, Programa de Pós Graduação em Microbiologia e Parasitologia, Universidade Federal de Pelotas, Pelotas, Brazil. danielabrayer@gmail.com.
Botton, Sônia Avila
  • Centro de Ciências da Saúde, Departamento de Microbiologia e Parasitologia, Laboratório de Pesquisas Micológicas, Programa de Pós-Graduação em Ciências Farmacêuticas, Universidade Federal de Santa Maria, Santa Maria, RS, Brasil.
Ianiski, Lara Baccarin
  • Centro de Ciências da Saúde, Departamento de Microbiologia e Parasitologia, Laboratório de Pesquisas Micológicas, Programa de Pós-Graduação em Ciências Farmacêuticas, Universidade Federal de Santa Maria, Santa Maria, RS, Brasil.
Braga, Caroline Quintana
  • Instituto de Biologia, Departamento de Microbiologia e Parasitologia, Laboratório de Micologia, Programa de Pós Graduação em Microbiologia e Parasitologia, Universidade Federal de Pelotas, Pelotas, Brazil.
Maciel, Aline Fontanella
  • Centro de Ciências da Saúde, Departamento de Microbiologia e Parasitologia, Laboratório de Pesquisas Micológicas, Programa de Pós-Graduação em Ciências Farmacêuticas, Universidade Federal de Santa Maria, Santa Maria, RS, Brasil.
Melo, Luíze Garcia
  • Instituto de Biologia, Departamento de Microbiologia e Parasitologia, Laboratório de Micologia, Programa de Pós Graduação em Microbiologia e Parasitologia, Universidade Federal de Pelotas, Pelotas, Brazil.
Zambrano, Cristina Gomes
  • Instituto de Biologia, Departamento de Microbiologia e Parasitologia, Laboratório de Micologia, Programa de Pós Graduação em Microbiologia e Parasitologia, Universidade Federal de Pelotas, Pelotas, Brazil.
Bruhn, Fábio Raphael Pascoti
  • Faculdade de Veterinária, Departamento de Medicina Veterinária Preventiva, Universidade Federal de Pelotas, Programa de Pós-Graduação em Medicina Veterinária, Pelotas, RS, Brazil.
Santurio, Janio Morais
  • Centro de Ciências da Saúde, Departamento de Microbiologia e Parasitologia, Laboratório de Pesquisas Micológicas, Programa de Pós-Graduação em Ciências Farmacêuticas, Universidade Federal de Santa Maria, Santa Maria, RS, Brasil.

MeSH Terms

  • Animals
  • Female
  • Male
  • Brazil / epidemiology
  • History, 21st Century
  • Horse Diseases / diagnosis
  • Horse Diseases / drug therapy
  • Horse Diseases / epidemiology
  • Horse Diseases / parasitology
  • Horses / parasitology
  • Pythiosis / diagnosis
  • Pythiosis / drug therapy
  • Pythiosis / epidemiology
  • Pythiosis / parasitology
  • Pythium / isolation & purification

Grant Funding

  • Financial code 001 / Coordenação de Aperfeiçoamento de Pessoal de Nível Superior
  • Conselho Nacional de Desenvolvimento Científico e Tecnológico / Conselho Nacional de Desenvolvimento Científico e Tecnológico

Conflict of Interest Statement

The authors declare that they have no conflict of interest.

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Citations

This article has been cited 2 times.
  1. Jaturapaktrarak C, Sae-Chew P, Rujirawat T, Reamtong O, Krajaejun T. Immunoproteomic approach identifies a putative virulence chaperone DnaK protein as a candidate diagnostic marker and therapeutic target for Pythium insidiosum infection.. Heliyon 2025 Feb 28;11(4):e42487.
    doi: 10.1016/j.heliyon.2025.e42487pubmed: 41477492google scholar: lookup
  2. Vasconcelos AB, França DA, Prado ACD, Yamauchi DH, Silva ACAD, Barros IO, Valença SRFA, Lucheis SB, Bosco SMG. Molecular Detection of Pythium insidiosum in Cutaneous Lesions of Horses from Northeastern Brazil.. Animals (Basel) 2025 Sep 30;15(19).
    doi: 10.3390/ani15192863pubmed: 41096457google scholar: lookup
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