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Applied and environmental microbiology2005; 71(10); 6418-6422; doi: 10.1128/AEM.71.10.6418-6422.2005

Equine and canine Anaplasma phagocytophilum strains isolated on the island of Sardinia (Italy) are phylogenetically related to pathogenic strains from the United States.

Abstract: The presence of Anaplasma phagocytophilum, a tick-transmitted zoonotic pathogen, was investigated in Sardinia using a molecular approach. Phylogenetic analysis revealed that Sardinian strains are genetically distinct from the two lineages previously described in Europe and are closely related to strains isolated in different areas of the United States.
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Publication Date: 2005-10-06 PubMed ID: 16204571PubMed Central: PMC1265917DOI: 10.1128/AEM.71.10.6418-6422.2005Google Scholar: Lookup
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  • Journal Article

Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

The research investigates the presence of the tick-transmitted zoonotic pathogen, Anaplasma phagocytophilum, in Sardinia, Italy. The study found that the strains of the pathogen in Sardinia are genetically unique compared to those present in other parts of Europe, but surprisingly are closely related to strains found in the United States.

Research Objective and Methodology

  • The main objective of this research was to investigate the presence and characteristics of Anaplasma phagocytophilum, a pathogen causing diseases in both animals and humans, in Sardinia – an Italian island.
  • The researchers utilized a molecular approach to identify and analyze the strains of this bacterium. This methodology allowed them to accurately determine the species of the pathogen and study its evolutionary relationships.

Findings and Results

  • The researchers discovered that the Anaplasma phagocytophilum strains isolated in Sardinia were genetically distinct from the strains previously identified in other parts of Europe.
  • This suggests that the evolution of these strains might have been influenced by specific environmental factors or demographic characteristics of Sardinia.
  • Interestingly, despite being geographically distant from the US, the Sardinian strains were found to be genetically close to the Anaplasma phagocytophilum strains identified in different areas of America. This unexpected relationship could possibly be explained by long-range migration of infected animals or ticks.

Significance and Implications

  • The findings provide important insights into the genetic diversity and geographical dispersion of Anaplasma phagocytophilum. Such information can help in enhancing our understanding of the disease dynamics and designing more effective control and prevention strategies.
  • The unexpected genetic similarity between Sardinian and American strains sheds light on the potential for global spread of certain strains of this pathogen.
  • The research emphasizes the necessity of continuous surveillance and research to monitor the changes in the distribution and genetic composition of zoonotic pathogens like Anaplasma phagocytophilum.

Cite This Article

APA
Alberti A, Zobba R, Chessa B, Addis MF, Sparagano O, Pinna Parpaglia ML, C뻝u T, Pintori G, Pittau M. (2005). Equine and canine Anaplasma phagocytophilum strains isolated on the island of Sardinia (Italy) are phylogenetically related to pathogenic strains from the United States. Appl Environ Microbiol, 71(10), 6418-6422. https://doi.org/10.1128/AEM.71.10.6418-6422.2005

Publication

Applied and environmental microbiology
ISSN: 0099-2240
NlmUniqueID: 7605801
Country: United States
Language: English
Volume: 71
Issue: 10
Pages: 6418-6422

Researcher Affiliations

Alberti, Alberto
  • Istituto di Patologia Speciale e Clinica Medica Veterinaria, Università degli Studi di Sassari, Via Vienna 2, 07100 Sassari, Italy. alberti@uniss.it
Zobba, Rosanna
    Chessa, Bernardo
      Addis, Maria Filippa
        Sparagano, Olivier
          Pinna Parpaglia, Maria Luisa
            C뻝u, Tiziana
              Pintori, Gianpaolo
                Pittau, Marco

                  MeSH Terms

                  • Anaplasma / classification
                  • Anaplasma / genetics
                  • Anaplasma / isolation & purification
                  • Anaplasma phagocytophilum / classification
                  • Anaplasma phagocytophilum / genetics
                  • Anaplasma phagocytophilum / isolation & purification
                  • Anaplasma phagocytophilum / pathogenicity
                  • Animals
                  • Chaperonin 60 / genetics
                  • Dog Diseases / epidemiology
                  • Dog Diseases / microbiology
                  • Dogs
                  • Ehrlichiosis / epidemiology
                  • Ehrlichiosis / microbiology
                  • Ehrlichiosis / veterinary
                  • Horse Diseases / epidemiology
                  • Horse Diseases / microbiology
                  • Horses
                  • Humans
                  • Italy / epidemiology
                  • Molecular Sequence Data
                  • Phylogeny
                  • Polymerase Chain Reaction
                  • Polymorphism, Restriction Fragment Length
                  • Sequence Analysis, DNA
                  • Tick Infestations / veterinary
                  • United States / epidemiology

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