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Annals of the New York Academy of Sciences2003; 990; 259-263; doi: 10.1111/j.1749-6632.2003.tb07374.x

Equine ehrlichiosis in Italy.

Abstract: The authors review equine granulocytic ehrlichiosis (EGE) in Italy from 1996 to 2002. In 1996, the first case of EGE has been observed in a horse affected with specific symptomatology (fever, lethargy, anorexia, limb edema, thrombocytopenia, and petechiae). In 1997, a seroepidemiological survey was performed in the province of Rome on 563 animals using IFAT. The authors describe the last case, which occurred on 2002 in a 15-year-old male, bay, half-breed, tick-infested horse. Clinical features included fever, lethargy, limb edema, icterus, leukocytopenia, and thrombocytopenia. Laboratory tests were positive for ELISA and IFAT and several morulae were seen in the cytoplasm of neutrophils in buffy coat smears. The authors think that in Italy the prevalence of EGE is underestimated because of the nonpathognomonic clinical symptoms, the diffusion of specific infected vector, and the nonroutine nature of specific laboratory tests.
Publication Date: 2003-07-16 PubMed ID: 12860637DOI: 10.1111/j.1749-6632.2003.tb07374.xGoogle Scholar: Lookup
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  • Journal Article

Summary

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This study is a review of the occurrence and presentation of equine granulocytic ehrlichiosis (EGE), a tick-borne disease in horses, in Italy from 1996 to 2002.

Objective of research

  • The purpose of this research is to analyze the cases of equine granulocytic ehrlichiosis (EGE) in Italy from 1996 to 2002 in order to gain a better understanding of the disease’s manifestation in the country.

Methodology

  • The authors observe and study various cases of EGE in Italy starting from its first reported case in 1996 up to the year 2002.
  • A seroepidemiological survey was done in the province of Rome in 1997 where 563 animals were examined using Indirect Fluorescent Antibody Test (IFAT).
  • The latest case described is from 2002 which was diagnosed with the help of laboratory tests like ELISA (Enzyme-linked Immunosorbent Assay) and IFAT. They also observed the presence of morulae (clusters of bacteria) in the neutrophils of the horse’s blood.

Findings

  • In all observed cases, the common clinical symptoms of the disease were fever, lethargy, limb edema (swelling), and thrombocytopenia (low platelet count). Some animals also demonstrated anorexia and petechiae (pinpoint, round spots that appear on the skin as a result of bleeding), and icterus (jaundice or yellowing of the skin).
  • According to the authors, the prevalence of EGE is likely underestimated in Italy due to its non-specific clinical symptoms, the spread of specific infected vector (ticks), and the fact that specific laboratory tests are not routinely done.

Significance of research

  • This review plays a vital role in understanding the occurrence and management of EGE in the equestrian community in Italy over a six-year period.
  • It also emphasizes the need for more specific and routine testing to properly gauge the prevalence of EGE amongst horses in Italy.

Cite This Article

APA
Scarpulla M, Caristo ME, Macri G, Lillini E. (2003). Equine ehrlichiosis in Italy. Ann N Y Acad Sci, 990, 259-263. https://doi.org/10.1111/j.1749-6632.2003.tb07374.x

Publication

ISSN: 0077-8923
NlmUniqueID: 7506858
Country: United States
Language: English
Volume: 990
Pages: 259-263

Researcher Affiliations

Scarpulla, Manuela
  • Istituto Zooprofilattico Sperimentale delle Regioni Lazio e Toscana, Rome, Italy.
Caristo, Maria Emiliana
    Macri, Gladia
      Lillini, Eugenio

        MeSH Terms

        • Animals
        • Ehrlichiosis / epidemiology
        • Ehrlichiosis / transmission
        • Ehrlichiosis / veterinary
        • Enzyme-Linked Immunosorbent Assay
        • Fluorescent Antibody Technique, Indirect
        • Horse Diseases / epidemiology
        • Horse Diseases / microbiology
        • Horses
        • Italy / epidemiology
        • Male
        • Tick Infestations / veterinary

        Citations

        This article has been cited 1 times.
        1. Laamari A, Azzag N, Tennah S, Derdour SY, China B, Boꯚllah R, Ghalmi F. Seroprevalence of Antibodies Against Anaplasma Phagocytophilum and Borrelia Burgdorferi in Horses (Equus Caballus) from Northern Algeria.. J Vet Res 2020 Sep;64(3):413-419.
          doi: 10.2478/jvetres-2020-0045pubmed: 32984632google scholar: lookup