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Equine eosinophilic enterocolitis.

Abstract: A 4-year-old Morgan stallion was presented with a 9-week history of diarrhea. Biopsy of nodules in the rectal mucosa yielded a diagnosis of eosinophilic enterocolitis. Treatment with steroids was instituted and the feces firmed within 2 days. Continued treatment with oral prednisone kept the feces at a normal consistency for 4 months.
Publication Date: 2000-01-11 PubMed ID: 11126494PubMed Central: PMC1476428
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Summary

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This study documents a case of eosinophilic enterocolitis in a 4-year-old Morgan stallion with a history of diarrhea, which was treated successfully with steroids.

Case Description

In this case, a 4-year-old Morgan stallion was brought to attention due to persistent diarrhea for 9 weeks. Key highlights from the case are detailed below:

  • The examination, diagnosis, and treatment were directed towards eosinophilic enterocolitis – a rare, severe condition characterized by infiltration of eosinophils in the gastrointestinal tract which is believed to be a form of a severe allergic reaction.
  • The diagnosis was made through biopsy of nodules in the rectal mucosa. These nodules were formed due to inflammation and abnormal accumulation of eosinophils, along with other inflammatory signs in the mucosal tissue.

Treatment and Outcome

The article also sheds light on the treatment administered and the corresponding outcome:

  • A treatment plan was initiated using steroids which play a role in reducing inflammation and are quite often used in eosinophilic disorders. In this case, steroids significantly improved the horse’s clinical condition.
  • In as short as two days, the feces of the horse firmed up, indicating the stool returned to normal form and marked a significant positive response to the steroid treatment.
  • Continued treatment with oral prednisone was provided and helped maintain normal feces consistency for 4 months. Prednisone is a synthetic form of corticosteroid which mimics hormones that are naturally produced by the adrenal gland. It helps reduce inflammation and suppresses the immune system, contributing to control of eosinophilic enterocolitis symptoms.

The report identifies a rare gastrointestinal disorder in horses and contributes valuable insights linked to its diagnosis and treatment. Focused on a single case, the study emphasizes the beneficial role of steroids in the management of eosinophilic enterocolitis in equines. Further research may be beneficial to assess the effectiveness of these treatments on a larger scale.

Cite This Article

APA
Kostiuk D. (2000). Equine eosinophilic enterocolitis. Can Vet J, 41(11), 871-872.

Publication

ISSN: 0008-5286
NlmUniqueID: 0004653
Country: Canada
Language: English
Volume: 41
Issue: 11
Pages: 871-872

Researcher Affiliations

Kostiuk, D
  • Western College of Veterinary Medicine, University of Saskatchewan, Saskatoon, Saskatchewan S7N 5B4.

MeSH Terms

  • Adrenal Cortex Hormones / therapeutic use
  • Animals
  • Diarrhea / veterinary
  • Enterocolitis / diagnosis
  • Enterocolitis / drug therapy
  • Enterocolitis / veterinary
  • Eosinophilia / diagnosis
  • Eosinophilia / drug therapy
  • Eosinophilia / veterinary
  • Feces / chemistry
  • Horse Diseases / diagnosis
  • Horse Diseases / drug therapy
  • Horses
  • Male
  • Weight Loss

References

This article includes 5 references
  1. Equine Vet J. 1991 Sep;23(5):344-6
    pubmed: 1959524
  2. Equine Vet J. 1987 May;19(3):247-52
    pubmed: 3608966
  3. Vet Pathol. 1985 Jul;22(4):297-305
    pubmed: 2930933
  4. Vet Pathol. 1982 Sep;19(5):486-96
    pubmed: 7147608
  5. Vet Pathol. 1974;11(6):535-47
    pubmed: 4466032

Citations

This article has been cited 1 times.
  1. Kranenburg LC, Bouwmeester BF, van den Boom R. Findings and Prognosis in 149 Horses with Histological Changes Compatible with Inflammatory Bowel Disease. Animals (Basel) 2024 May 30;14(11).
    doi: 10.3390/ani14111638pubmed: 38891685google scholar: lookup