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Equine veterinary journal2025; doi: 10.1111/evj.14528

Equine epiglottitis: Diagnosis, treatment and outcome.

Abstract: Epiglottitis is an uncommon upper airway pathology manifested endoscopically by mucosal oedema, reddening and thickening of the epiglottic mucosa. Literature on epiglottitis in horses is sparse. Objective: To describe the diagnosis, treatment and outcome of Thoroughbred and Standardbred racehorses diagnosed with epiglottitis at a single centre. A secondary objective is to demonstrate the efficacy of inhaled and topical anti-inflammatories for this condition. Methods: Retrospective case series. Methods: Medical records (2009-2023) were reviewed for racehorses treated for epiglottitis. Data collected included signalment, history, endoscopic findings, treatment progression, hospitalisation duration and any reason for re-admission. Race records were obtained to determine days to first race, earnings and career length. Results: Twenty-four horses were included in the study. Horses were referred for a variety of upper airway abnormalities including epiglottic entrapment, dysphagia and respiratory stridor. Of the horses admitted for epiglottic entrapment (18), a more accurate diagnosis of epiglottitis was made based on admission endoscopy. Horses were treated with systemic, topical and inhaled anti-inflammatories, as well as topical and inhaled antimicrobials. Twenty-two horses (91.6%) returned to racing after discharge. Eight horses (33.3%) were re-admitted, including six for recurrent epiglottitis and two for other airway pathologies. Conclusions: The major limitations include those inherent to a retrospective report. The results would be stronger with higher case numbers. Additionally, we did not have sufficient case numbers to compare outcomes of horses treated with inhaled medications versus those that were not. Racehorses inevitably develop other racing-related problems which confound studies of this nature. Conclusions: Epiglottitis is a rare upper airway condition that is challenging to diagnose. However, when accurately identified, it can be successfully treated, offering a good prognosis for a return to athletic function.
Publication Date: 2025-05-15 PubMed ID: 40371873DOI: 10.1111/evj.14528Google Scholar: Lookup
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  • Journal Article

Summary

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This research article discusses the diagnosis, treatment, and outcome of epiglottitis in racehorses. The researchers found that despite being a challenging condition to accurately diagnose, successful treatment can provide a positive prognosis for a return to racing.

Research Objectives

  • The primary objective of this study was to provide a detailed analysis of the diagnosis, treatment, and outcome of Thoroughbred and Standardbred racehorses diagnosed with epiglottitis at a single center.
  • The secondary objective was to assess the effectiveness of inhaled and topical anti-inflammatory treatments for epiglottitis in horses.

Research Methodology

  • The researchers employed a retrospective case series method, reviewing medical records from 2009-2023 of racehorses treated for epiglottitis.
  • Data collected for the study included the horses’ background (signalment), medical history, endoscopic findings, details of treatment progression, duration of hospitalisation, and reasons for re-admission, if any.
  • Racing records were also collected to determine the number of days till the first race post-treatment, earnings, and length of racing career for each horse.

Research Findings

  • The study sample comprised twenty-four horses. Horses were initially referred due to a variety of upper respiratory problems including, but not limited to, epiglottic entrapment, difficulty swallowing (dysphagia), and noisy breathing due to a narrowed airway (respiratory stridor).
  • Of the horses admitted for what was assumed to be an entrapped epiglottis, a diagnosis of epiglottitis was confirmed instead, based on careful endoscopic examination during admission.
  • The treatments used included systemic, topical, and inhaled anti-inflammatories, as well as topical and inhaled antimicrobials.
  • Of the 24 horses treated, 22 (91.6%) were able to resume racing after their discharge from the hospital, indicating a positive prognosis with accurate diagnosis and successful treatment.
  • Approximately 33.3% (eight) of the horses were re-admitted, with six having a recurrence of epiglottitis and the other two presenting different airway issues.

Research Limitations

  • Limitations of this study include those common to a retrospective study design.
  • The results could be constrained due to the small sample size and the lack of enough case numbers to compare the outcome of horses treated with inhaled medications versus those that were not.
  • The researchers also took into account that racehorses often develop other issues related to racing, which can complicate and potentially skew studies of this nature.

Conclusion

  • Despite epiglottitis being a rare and challenging-to-diagnose condition in racehorses, this study has demonstrated that once accurately identified and effectively treated, it offers a favourable prognosis for the horse’s return to athletic function.

Cite This Article

APA
Jimenez C, Hogan P, Belaghi R, Curtiss A. (2025). Equine epiglottitis: Diagnosis, treatment and outcome. Equine Vet J. https://doi.org/10.1111/evj.14528

Publication

ISSN: 2042-3306
NlmUniqueID: 0173320
Country: United States
Language: English

Researcher Affiliations

Jimenez, Carlos
  • SLU University Animal Hospital (UDS), Equine Hospital, Uppsala, Sweden.
Hogan, Patricia
  • Hogan Equine LLC, Cream Ridge, New Jersey, USA.
Belaghi, Reza
  • SLU University (UDS), Department of Energy and Technology, Unit of Applied Statistics and Mathematics, Uppsala, Sweden.
Curtiss, Alexandra
  • Hogan Equine LLC, Cream Ridge, New Jersey, USA.

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