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Equine veterinary education2016; 30(3); 151-160; doi: 10.1111/eve.12559

Equine faecal microbiota transplant: Current knowledge, proposed guidelines and future directions.

Abstract: While certainly not a novel concept, faecal microbiota transplant (FMT) has recently garnered renewed interest in veterinary medicine due to its remarkable success in treating recurrent Clostridium difficile infection (CDI) in man. There is a dearth of information on indications and efficacy of FMT for the treatment of gastrointestinal disorders in the horse; however, based on evidence in man and other veterinary species, and anecdotal reports in horses, FMT may be a useful treatment for selected cases of acute and chronic diarrhoea and inflammatory bowel disease (IBD) in the horse. In the absence of evidence, expert opinion is offered on case selection and FMT procedure. More research is needed to explore the efficacy, indications and optimal preparation, storage and delivery of FMT to horses.
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Publication Date: 2016-02-28 PubMed ID: 32313396PubMed Central: PMC7159401DOI: 10.1111/eve.12559Google Scholar: Lookup
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Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

The study explores the potential for Fecal Microbiota Transplant (FMT) in treating gastrointestinal disorders in horses. It further encourages the need for more research to determine the optimal ways to implement FMT in equine veterinary medicine.

Understanding Fecal Microbiota Transplant (FMT)

  • Fecal Microbiota Transplant (FMT) is a procedure that involves the transfer of fecal matter from a healthy individual to another individual in order to restore the balance of their gut microbiota.
  • This technique has attracted wider attention in veterinary medicine following its successful use in treating Clostridium difficile infections (CDIs) in humans.

Application of FMT in Equines

  • There is limited information on the use of FMT in treating horses suffering from gastrointestinal disorders, but based on its effectiveness in humans and other animals, and anecdotal reports from horse owners, it may prove beneficial.
  • Particular case studies suggest that this treatment approach could be especially useful in handling acute and chronic diarrhoea, as well as inflammatory bowel disease (IBD) in horses.

Need for Further Research

  • Despite the promising potential of FMT in equine treatment, this area of research is still in its infancy and, consequently, there is a need for more scientific studies.
  • Specifically, the researchers point out the necessity for more extensive research to understand the efficacy, indications as well as optimal strategies for the preparation, storage and delivery of fecal matter for effective FMT in horses.

Suggested Guidelines for FMT in Equines

  • In the paper, the authors also propose guidelines on case selection for FMT and the procedure itself in the context of equine treatment.
  • These preliminary guidelines are essentially based on expert opinion and are intended to inform clinical practice until more empirical evidence becomes available.

Cite This Article

APA
Mullen KR, Yasuda K, Divers TJ, Weese JS. (2016). Equine faecal microbiota transplant: Current knowledge, proposed guidelines and future directions. Equine Vet Educ, 30(3), 151-160. https://doi.org/10.1111/eve.12559

Publication

Equine veterinary education
ISSN: 0957-7734
NlmUniqueID: 9885274
Country: England
Language: English
Volume: 30
Issue: 3
Pages: 151-160

Researcher Affiliations

Mullen, K R
  • Littleton Equine Medical Center Colorado USA.
Yasuda, K
  • Harvard T.H. Chan School of Public Health Boston Massachusetts USA.
Divers, T J
  • Department of Clinical Sciences Cornell University College of Veterinary Medicine Ithaca New York USA.
Weese, J S
  • Department of Pathobiology Ontario Veterinary College University of Guelph Canada.

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