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Equine glaucoma: a retrospective study of 13 cases presented at the Western College of Veterinary Medicine from 1992 to 1999.

Abstract: The prevalence of equine glaucoma seen by the ophthalmology service at the Western College of Veterinary Medicine (WCVM) was 6.5%. The majority of cases (11/13) were associated with clinical manifestations of uveitis. Congenital glaucoma was documented in 1 case, and primary glaucoma was diagnosed in a 12-year-old quarter horse. There were no breed or sex predilections evident. Affected horses were middle-aged to old (average age = 9.5 years, ranging from 2 weeks to 23 years). The clinical manifestations of equine glaucoma included blindness, diffuse corneal edema, corneal vascularization, buphthalmia, corneal striae, recurrent secondary ulcerative keratitis, and less commonly, iris bombé, tapetal hyper-reflectivity, complete pupillary occlusion from posterior synechiae, and optic disc cupping. Elevated intraocular pressure confirmed the diagnosis (n = 10), while 3 cases were normotensive with signs of glaucoma including corneal striae and buphthalmia. Affected eyes were treated medically and/or surgically. Regardless of the therapy instituted, the visual outcome was poor. Most affected eyes were blind at presentation or became blind within a few weeks.
Publication Date: 2000-06-17 PubMed ID: 10857031PubMed Central: PMC1476223
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Summary

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The research conducted at the Western College of Veterinary Medicine (WCVM) studied cases of glaucoma in horses, a condition that was witnessed in 6.5% of the horses. The condition was primarily found connected with manifestations of uveitis and was most prevalent in mid-age to old horses, showing varying clinical signs. Different medical and surgical treatments were applied, however, the visual outcome remained unfavorable as most affected horses either already presented blindness or developed it within weeks.

Context of the Study

  • The study was based on equine glaucoma cases reported at the Western College of Veterinary Medicine (WCVM) during 1992 to 1999.
  • The research sought to understand the prevalence, associated conditions, manifestation, and treatment outcomes of glaucoma in horses, a condition commonly causing irreversible blindness.

Findings on Prevalence

  • Over a 7-year period, the prevalence of equine glaucoma recorded by WCVM’s ophthalmology service was 6.5%.

Associated Conditions

  • Most cases of glaucoma were associated with clinical manifestations of another eye disease known as uveitis.
  • A single case showed congenital glaucoma, a condition present since birth, and primary glaucoma, resulting not from another disease but an imbalance in eye fluid production, was also diagnosed in one 12-year-old horse.

Clinical Manifestations

  • Manifestations included blindness, corneal edema, corneal vascularization, buphthalmia, corneal striae, recurrent ulcerative keratitis, and others less common signs like, optic disc cupping and iris bombé.
  • The average age of the affected horse was middle-aged to old (average age = 9.5 years), and no correlations were found with breed or sex.

Diagnosis and Treatment

  • The diagnostic confirmation of glaucoma was done by measuring elevated intraocular pressure. However, three cases were normotensive yet showed signs of glaucoma.
  • Treatments on affected eyes comprised of a mixture of medical and surgical procedures.

Outcomes of Treatment

  • Despite the implemented therapy, the visual prognosis was poor for most of the treated horses.
  • Most affected horses were already blind upon presentation or developed blindness within a few weeks, thus indicating the severe and often irreversible nature of equine glaucoma.

Cite This Article

APA
Cullen CL, Grahn BH. (2000). Equine glaucoma: a retrospective study of 13 cases presented at the Western College of Veterinary Medicine from 1992 to 1999. Can Vet J, 41(6), 470-480.

Publication

ISSN: 0008-5286
NlmUniqueID: 0004653
Country: Canada
Language: English
Volume: 41
Issue: 6
Pages: 470-480

Researcher Affiliations

Cullen, C L
  • Department of Veterinary Internal Medicine, Western College of Veterinary Medicine, University of Saskatchewan, Saskatoon.
Grahn, B H

    MeSH Terms

    • Animals
    • Blindness / etiology
    • Blindness / veterinary
    • Diagnosis, Differential
    • Female
    • Glaucoma / epidemiology
    • Glaucoma / pathology
    • Glaucoma / veterinary
    • Horse Diseases / epidemiology
    • Horse Diseases / pathology
    • Horse Diseases / therapy
    • Horses
    • Incidence
    • Male
    • Prognosis
    • Retrospective Studies

    References

    This article includes 13 references
    1. J Am Vet Med Assoc. 1970 Jun 15;156(12):1884-7
      pubmed: 5420729
    2. Am J Vet Res. 1985 Jan;46(1):84-8
      pubmed: 2578758
    3. Am J Vet Res. 1986 Nov;47(11):2445-53
      pubmed: 3789508
    4. Equine Vet J. 1988 Mar;20(2):132-5
      pubmed: 3371317
    5. J Am Vet Med Assoc. 1988 Aug 1;193(3):343-5
      pubmed: 3182386
    6. Equine Vet J Suppl. 1990 Sep;(10):36-8
      pubmed: 9079115
    7. J Glaucoma. 1998 Jun;7(3):187-201
      pubmed: 9627859
    8. J Am Vet Med Assoc. 1991 Oct 15;199(8):1049-50
      pubmed: 1748609
    9. Vet Pathol. 1991 Jan;28(1):74-8
      pubmed: 2017829
    10. Vet Pathol. 1990 Jan;27(1):41-5
      pubmed: 2309380
    11. Am J Vet Res. 1989 May;50(5):720-7
      pubmed: 2729716
    12. J Morphol. 1988 Oct;198(1):33-42
      pubmed: 3199448
    13. Equine Vet J Suppl. 1990 Sep;(10):30-5
      pubmed: 9079114